Rhizobium etli CFN 42: RHE_CH00024
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Entry
RHE_CH00024 CDS
T00317
Symbol
folC
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate syntase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
ret
Rhizobium etli CFN 42
Pathway
ret00790
Folate biosynthesis
ret01100
Metabolic pathways
ret01240
Biosynthesis of cofactors
Module
ret_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
ret00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
RHE_CH00024 (folC)
Enzymes [BR:
ret01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
RHE_CH00024 (folC)
6.3.2.17 tetrahydrofolate synthase
RHE_CH00024 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
BPD_transp_1_N
Motif
Other DBs
NCBI-ProteinID:
ABC88857
RhizoBase:
RHE_CH00024
UniProt:
Q2KE79
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Position
20620..21915
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AA seq
431 aa
AA seq
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MGLHPKGFDLSLDRITRLLDRLGNPHRKLPPVVHVAGTNGKGSVTAFCRALLEAGGYSAH
VHTSPHLVNWHERYRIGVAGGRGQLVDDAVFAEAVRRVAEANAGQHITVFEILTAVTFIL
FSEHPADAAIIEVGLGGRFDATNVISDPAVSVIMPISLDHQPYLGDRVELIAAEKAGIMK
PGLPVVIGHQEYDAALDVLMSTAERLHCPSAVFGQDFMAHEEYGRLVYQDEYGLADLPLP
RLPGRHQYANAAAAIRAVKAAGFTVTETMMEKAMNCVEWPGRLQRLSEGRLLSHAPLGAE
IWVDGGHNPGAGEVIAEAMASFEERQPRPLFLIIGMINTKDPIGYFKAFTGLVEKVFCVP
IRGSDAMIDPVILSNAAYDAGLVAEPMSTVGDALEAIKTALQPAALPPRILVGGSLYLVG
DVLTDNGTPPK
NT seq
1296 nt
NT seq
+upstream
nt +downstream
nt
atgggattgcatcccaaggggttcgatctgtctctcgatcgcatcacccgtctcctcgac
cgacttggcaatccgcacaggaaactgccaccggtggtccatgtcgccggcaccaacggc
aagggctcggtcaccgctttctgccgcgctttgcttgaagccggcggctacagcgcccat
gtccatacctcgccgcatctcgtcaattggcacgagcgttatcgcatcggtgtggcgggc
ggacgcgggcaactcgtcgatgatgccgtctttgccgaggccgtgcgccgcgtggccgag
gccaatgccggtcagcacatcaccgtcttcgagattctgacggcggtcactttcattctg
ttttccgaacatccggccgatgctgcgatcatcgaagttggcctcggcggccgtttcgac
gccaccaatgttatttccgatccggccgtctcggtcattatgccgatctcgctcgatcat
cagccctatctcggcgacagggtcgaactgattgcagccgaaaaggccggcatcatgaag
ccgggactgcctgtcgtcatcggtcaccaggaatatgatgccgcgctcgatgtgctgatg
tcgacggccgaacggctgcattgcccgagcgcggttttcgggcaggatttcatggcccat
gaggaatatgggcggcttgtctatcaggacgaatacggccttgccgacctgccgctgccg
cgtcttcccggtcgccatcaatacgccaatgccgccgccgccatccgcgccgtcaaggcg
gcgggtttcaccgtcaccgagacgatgatggaaaaggcgatgaattgcgtggaatggccg
ggccggctgcagcgcctgagcgaaggccggctgctgtcgcatgccccgctcggcgccgag
atctgggtcgatggcgggcataatcccggcgccggcgaagtgatcgccgaagccatggcc
agtttcgaggagcgccagccgcggccgcttttcctgatcatcggcatgatcaacaccaag
gatccgatcggctatttcaaggccttcacaggtctggtcgagaaggtgttctgcgtaccg
atccgtggcagcgacgcgatgatcgatccggtgatattatcgaacgccgcctatgatgcc
ggtttggttgccgaaccgatgtcgacggtcggcgatgcgctggaagcgataaaaacggca
ctccagccggcggcactgccgccccgcatccttgtcggcggctctctctacctcgtcggc
gatgtgcttaccgacaacggcacgcccccgaaatag
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