KEGG   Cupriavidus pinatubonensis JMP134: Reut_B4976
Entry
Reut_B4976        CDS       T00268                                 
Name
(GenBank) Pyruvate dehydrogenase (lipoamide)
  KO
K00166  2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
Organism
reu  Cupriavidus pinatubonensis JMP134
Pathway
reu00280  Valine, leucine and isoleucine degradation
reu00640  Propanoate metabolism
reu00785  Lipoic acid metabolism
reu01100  Metabolic pathways
reu01110  Biosynthesis of secondary metabolites
reu01210  2-Oxocarboxylic acid metabolism
Module
reu_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:reu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    Reut_B4976
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    Reut_B4976
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    Reut_B4976
Enzymes [BR:reu01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.4  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
     Reut_B4976
SSDB
Motif
Pfam: E1_dh DXP_synthase_N TPP_enzyme_C
Other DBs
NCBI-ProteinID: AAZ64324
UniProt: Q46RB0
LinkDB
Position
2:1703037..1704137
AA seq 366 aa
MGTVASFDIGYTRYLDPPGATPVSSSPLPPFANDPDALLPLYRAMVLTRQFDLKAIAMQR
TGKIGTFASALGQEAVGVGVASAMRPEDILVPSYRDHAAQFVRGVTMTESLLYWGGDERG
SGFAAAPHDFGNNVPIGTQVCHAAGVAYAVQLRGEPRVAVCMLGDGGTSKGDFYEGMNMA
GAWHAPLVIVVNNNQWAISMPRSRQTAAHTLAQKAIAAGIPGEQIDGNDVVAVRHRVGEA
IERARAGEGPSLIEAITYRLGDHTTADDASRYRDESTVKAHWQAEPLLRLREHLVKLGAW
DAGREEALVRECSQQVAQAVEAYLALPPPDPAAMFDCLYATMPAALQEQLATARRYAAPH
GQTNPN
NT seq 1101 nt   +upstreamnt  +downstreamnt
atgggcacggttgcgagctttgacatcggctacacacgatacctcgacccgccgggcgca
accccggtttcctcttcccctctcccgccattcgccaacgacccggacgcgctgctgccg
ctgtaccgtgcgatggtgctgacccgccagttcgacctcaaagccattgcgatgcagcgc
accggcaagatcggcacgttcgcatcggcgctcgggcaggaggcggtcggcgttggcgta
gccagcgcgatgcggcccgaggacatactggtgccgtcgtaccgcgatcacgccgcgcag
tttgtgcgcggcgtcaccatgaccgaaagcctgctgtactggggcggcgacgagcgcggc
agcggttttgcggcggcgccgcacgacttcggcaacaacgtgccgatcggcacgcaggtc
tgccatgcggcaggcgtggcttacgcggtgcagttgcgcggcgagccgcgcgtggcagtc
tgcatgcttggcgatggtggcacctcgaaaggcgatttctacgaggggatgaacatggcc
ggcgcgtggcatgcgccgctcgtgatcgtcgtcaacaacaaccagtgggccatttcgatg
ccgcgcagccgccagaccgctgcgcacacgctcgcgcaaaaagcgatcgccgcgggcatt
cccggcgagcagatcgacggcaatgatgtcgtggcagtgcgtcaccgcgtaggcgaagcg
atcgagcgtgcgcgcgccggcgagggaccatcgctgatcgaagcgatcacgtaccggctc
ggcgaccacaccacggctgacgatgcctcgcgctaccgtgacgagtccacggtcaaggcg
cactggcaggccgaaccgctgctcaggctgcgcgagcacctggtaaagctcggcgcgtgg
gatgcggggcgcgaagaagcgctggtgcgcgaatgctcgcagcaggtcgcgcaggccgtg
gaagcttacctggcgctgccgccgcccgatcccgccgcgatgttcgactgcctgtacgcg
accatgcccgcagcattgcaagagcagctcgcgacggcacggcgctatgccgcgccgcat
ggccagaccaacccgaactga

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