Rhinolophus ferrumequinum (greater horseshoe bat): 117022786
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Entry
117022786 CDS
T07722
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
rfq
Rhinolophus ferrumequinum (greater horseshoe bat)
Pathway
rfq00010
Glycolysis / Gluconeogenesis
rfq00020
Citrate cycle (TCA cycle)
rfq00620
Pyruvate metabolism
rfq00785
Lipoic acid metabolism
rfq01100
Metabolic pathways
rfq01200
Carbon metabolism
rfq01210
2-Oxocarboxylic acid metabolism
rfq04066
HIF-1 signaling pathway
rfq04922
Glucagon signaling pathway
rfq05230
Central carbon metabolism in cancer
rfq05415
Diabetic cardiomyopathy
Module
rfq_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
rfq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
117022786 (PDHA1)
00020 Citrate cycle (TCA cycle)
117022786 (PDHA1)
00620 Pyruvate metabolism
117022786 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
117022786 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
117022786 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
117022786 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
117022786 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
117022786 (PDHA1)
Enzymes [BR:
rfq01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
117022786 (PDHA1)
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
117022786
NCBI-ProteinID:
XP_032962807
Ensembl:
ENSRFEG00010009265
LinkDB
All DBs
Position
X:complement(111952430..111970618)
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AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLTVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEICLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDVLCVREATKFAASHCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSNEPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctcccgcgtgttgtcgggcgctgcccagaagccggca
agcagagtgctcgtggcatcccgtaattttgcaaacgatgctacatttgaaattaagaag
tgtgaccttcaccggctggaagagggccctcccgtcaccacggtgctcaccagggaggat
gggctcaaatactacaggatgatgcagactgttcgccgaatggagttaaaggcagatcag
ctgtacaagcagaaaattattcgtggtttctgtcacttgtgtgatggccaggaagcttgt
tgtgtgggcctggaggctggcataaatcccacagaccatctgatcacagcctatcgggct
catggctttaccttcactcgtgggcttactgtccgagaaattcttgcagagcttacagga
cgaagaggcggttgtgctaaaggaaaaggaggatcaatgcatatgtacgccaagaacttc
tacgggggcaatgggatcgttggagctcaggtgcccctgggagctggcattgcgctggcc
tgtaagtacaacgggaaagatgagatctgtctgactttatatggtgatggcgctgccaat
cagggtcagatatttgaagcttacaatatggcagctttgtggaaattaccttgtattttc
atctgtgaaaataaccgctatggaatgggaacgtctgttgagagagcagcagccagcacg
gattactataagagaggcgacttcattcctgggctgagggtagatggaatggatgtcctg
tgtgtccgggaggcgacaaagtttgcagcctctcactgtagatctggaaaggggcccatc
ctgatggaactgcagacttaccgttaccatgggcacagcatgagtgatcctggagttagt
tatcgtacacgagaagaaattcaggaagtgagaagtaagagtgacccgatcatgcttctc
aaggacagaatggtgaacagcaatcttgccagtgttgaagaattaaaggaaattgatgtt
gaagtgaggaaggaaattgaggacgcggcccagtttgctacagccgatcctgaaccgcct
ttggaagaactagggtatcacatctactccaacgagccaccttttgaagttcggggtgca
aatcagtggatcaagttcaagtccgtcagttaa
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