Rhodoferax sp. AJA081-3: HZ993_22685
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Entry
HZ993_22685 CDS
T08330
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
rhoa
Rhodoferax sp. AJA081-3
Pathway
rhoa00790
Folate biosynthesis
rhoa01100
Metabolic pathways
rhoa01240
Biosynthesis of cofactors
Module
rhoa_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
rhoa00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
HZ993_22685 (folC)
Enzymes [BR:
rhoa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
HZ993_22685 (folC)
6.3.2.17 tetrahydrofolate synthase
HZ993_22685 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
LPD39
Motif
Other DBs
NCBI-ProteinID:
QTN28020
UniProt:
A0A975E9L4
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Position
4853180..4854490
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AA seq
436 aa
AA seq
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MQTPTTLEAWLAHCERLHPTAIDMGLDRVRTVAQRMNIRFDCPVITVAGTNGKGSTCAML
ECILGQAGYRTGVFTSPHLVHFEERLRLQGQSVDATNLIAGFAAVEGARSLNGEVVSLSY
FEFSMLAIFEVMMRSNLDVVILEVGLGGRLDSTNIIDADCAIITSIDLDHMEILGPDRES
IGREKAGIMRTGRPVIVSDPVPPQSVLDHALEIGANLWRVGQDFNVSGDKQQWGWAGRGR
RYSGLAYPALRGANQLVNAAGVLAALTALRERLPVTAQAVRNGLAFVELPGRFQIIPGQP
TLVLDVAHNPHSVAALAANLDAMGYFPTTHAVFGAMADKDLASMFTKLLPLLDRWYFTDL
PLPRAAKGADLMAQWQALNTRKDAKGAAFADPMGALQAAIAAADPADRIVVFGSFHTVGG
VLANGVPRLQAKHLNS
NT seq
1311 nt
NT seq
+upstream
nt +downstream
nt
atgcaaactccaacaaccctagaagcctggctagcccactgcgagcgcctgcaccccacc
gccatcgacatgggcctggaccgcgtacgcaccgttgcccagcgcatgaacatccgcttc
gactgccccgtcatcaccgtggccggcaccaacggcaaaggctccacctgcgccatgctg
gaatgcattctgggtcaggccggctaccgcaccggcgtctttacatccccccacctggtc
cacttcgaggaacgcctgcgcctccaaggccaatccgtggatgctacgaacctgatagca
ggctttgcagcagtggagggggcgagaagcctaaatggcgaagtggtttccctcagctac
ttcgaattctcgatgttggccatcttcgaagtcatgatgcgcagcaacctggatgtagtg
atcctggaagtaggcctgggcggccggctggattccaccaacatcatcgacgccgattgc
gccatcattaccagcatcgacctggaccacatggaaattttgggtccggaccgcgaaagc
atcggccgcgagaaggccggcatcatgcgcaccggccgccccgtcatcgtcagcgacccc
gtgccgccgcaaagcgtgctggaccatgcgctggaaatcggtgcgaacctgtggcgcgtg
gggcaagacttcaacgtgtcgggcgataaacagcagtggggctgggccgggcgtgggcgc
cgttacagcgggctggcctacccggcgctgcgcggcgccaaccagttggtcaacgccgcc
ggtgtgctggccgcgctgaccgcgctgcgcgaacgcttacccgtcaccgcccaggccgtg
cgcaacggcctggcctttgtggaactgccaggccgcttccagatcatcccgggccagccc
acgttggtgctcgacgtggcgcacaacccgcactcggtggcggcgctggcggccaatctg
gacgccatgggctacttcccgaccacccatgccgtgtttggcgccatggccgacaaggac
ctggccagcatgttcaccaagctgctgccgctgctggaccgctggtatttcaccgatctg
ccgctgccccgcgccgccaaaggtgccgacctgatggcgcaatggcaagccctgaacacc
cgcaaggacgccaagggcgctgcctttgccgacccgatgggggcattgcaggcagccatc
gccgccgcagaccccgctgatagaatcgtcgtctttggatcgttccacaccgtgggcggc
gtgcttgcaaacggcgtgccccggctgcaggccaaacacctgaattcctga
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