Cupriavidus metallidurans: Rmet_2748
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Entry
Rmet_2748 CDS
T00351
Symbol
hemDX
Name
(GenBank) putative bifunctional protein (uroporphyrinogen-III synthase transmembrane protein and Uroporphyrin-III C-methyltransferase)
KO
K13543
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
rme
Cupriavidus metallidurans
Pathway
rme00860
Porphyrin metabolism
rme01100
Metabolic pathways
rme01110
Biosynthesis of secondary metabolites
rme01120
Microbial metabolism in diverse environments
rme01240
Biosynthesis of cofactors
Module
rme_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
Brite
KEGG Orthology (KO) [BR:
rme00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Rmet_2748 (hemDX)
Enzymes [BR:
rme01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Rmet_2748 (hemDX)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Rmet_2748 (hemDX)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HemX
HEM4
PspA_IM30
DUF948
Filament
DUF4407
Motif
Other DBs
NCBI-ProteinID:
ABF09621
UniProt:
Q1LJQ5
LinkDB
All DBs
Position
complement(2983756..2985837)
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AA seq
693 aa
AA seq
DB search
MPRPTVVVTRPAGQSRQLTEALQAAGLDVLSFPLLAIGPAADDVPLRAELGRIEDYALVV
FVSPNAVSYGLDTLAQVQNAPGGARWPESVPVAVVGPSSVVALAERGITPPAYRVIAPAG
AQGNDTAGDAARFDSEALWSELDTSPGAFAGRKVLIIRGSGGREWLADRLRDAGASVEAV
EAYSRTLPEPSGMQWQAVRDSLKPDAPPYAWLLTSSEAVRNLDGLARLHLSPQEHERLKQ
MQCIAPHARIAAQAQSLGFAHVLPAAPGDAGLLAACTQWGEAYAGPATPAPAPVSPAPAP
VVVQPEPEPTPAPMAPKEPTSTKVERVTTDTTSPSPNPGGNPGSSGMSGAFVTPARRMNP
WWLLVAVLVVAVAGGFWWLQMRVEHLTQELARRQQSADTLVQETRVLSRDAQETVKALQG
KVGALDGQITETRDKQAALEQVYQDLMRNRDDWEIAEIQQLLTNAGQQLQLTGNVQVALA
ALQSADARLARSDKPQYNQLRRAIARDIGRMKAVPDTDLTGAAIKLDEAINQIDSLPLLS
GERMLDRTPGEGNKPAPAAPKGASTPAAASATGGNMVSRLWTYVLDELGQVIRVRKVDDT
NALLLSGDQGWFLRENIKLRLLNARLALLSRNEPVFRNDLAAAQGMIARYCDTRSRRVQG
VLTMLKQAQASAVTVSLPTMAESLGALHALKKE
NT seq
2082 nt
NT seq
+upstream
nt +downstream
nt
atgcctcgcccgaccgtcgtagtaacacgacccgccgggcagtcccggcaactgaccgaa
gcgttacaggccgcgggtctcgacgtgctcagttttccgctgctggcgatcgggcccgcg
gccgatgacgtgccgctgcgcgccgagcttggccggatcgaggactacgcgctggtggtg
ttcgtgagcccgaacgcggtgtcctatggactggacacccttgctcaggtccagaacgcc
ccgggcggagcccggtggccggaaagcgtgccggtggccgtggtggggccatcgagcgtg
gttgcgctggcggaacggggtatcaccccgcccgcgtatcgcgtgatcgcgcctgctggc
gcgcagggtaatgacacggccggcgacgcagcgcgcttcgattcagaggcgctctggtcc
gaactcgacacctcgccgggcgcgtttgccggccgcaaggtcctgatcatccgtggcagc
ggcgggcgcgaatggctggccgatcgtctgcgcgacgccggcgcgtccgtcgaagccgtg
gaagcctacagccgcacgctgcccgagccgagcggcatgcaatggcaggccgtgcgcgac
agcctcaagcccgatgcgccgccgtacgcgtggctgctgaccagttcggaagccgtgcgc
aacctggacgggctggcgcgtttgcatctgtcgcctcaggaacacgaacgtctgaagcag
atgcagtgcatcgcaccacatgcgagaattgccgcgcaggcccagtcgctgggatttgcc
cacgtgctgcccgccgcgcccggagatgccgggctgctggccgcatgcacgcaatggggc
gaagcctatgctgggccggccacgccagcgcccgcccccgtatcgcctgcacccgctccg
gtggtcgtgcagccggaaccggagccgacaccggcgccaatggcacccaaggaacccacg
tcaaccaaagtcgaacgcgtgacgacagacaccacgtccccctcgccgaatccgggcggt
aaccccggtagttccggcatgtccggcgcatttgtgacacccgcgcgccgaatgaatcca
tggtggctgctcgtcgccgtgctggtggtcgccgttgccgggggcttctggtggttgcag
atgcgggtcgagcatctgacccaggaactggcgcgccgccagcagagcgcggacacgctg
gtgcaggaaacgcgggtgctgtcgcgcgatgcgcaggagacggtcaaggcgttgcagggc
aaggtgggcgcactcgacggccaaatcacggagacgcgcgacaagcaggccgcgctggaa
caggtctatcaggacctgatgcgcaaccgcgacgactgggaaatcgccgaaatccagcag
ttgctgaccaacgccggccagcagcttcagctcaccggcaacgtgcaggtggcgctggcc
gcgctgcaaagcgccgacgcgcgcctggcgcgctcggacaagccgcaatacaaccagctt
cgccgcgctattgcgcgcgatatcggtcggatgaaggccgtgccggataccgacctgacc
ggggcggcgatcaagcttgacgaggcgatcaaccagatcgattcattgccgctgctgtcg
ggcgagcggatgctcgaccgcacgcctggcgagggcaacaagccggcaccggccgcgccg
aagggcgcctcgacgcccgcggctgccagcgcgacgggtggcaatatggtgtcgcgactg
tggacgtacgtgcttgacgagcttggtcaggtgatccgcgtgcgcaaggtcgatgacacc
aacgcgctactgctctcgggtgaccagggctggttcctgcgcgagaacatcaagctgcgc
ctgctcaatgcgcggctggcgctactgtcgcgcaacgaaccggtcttccggaacgacctc
gccgccgcgcagggcatgatcgcgcgctattgcgatacccgttcgcgccgcgtgcagggc
gtgctgacgatgctcaagcaggcccaggccagcgcggtgacggtatccctgccgacgatg
gcggagagcctcggcgcgttgcatgccctgaagaaggagtag
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