Romboutsia sp. CE17: HF520_11945
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Entry
HF520_11945 CDS
T06535
Symbol
cobA
Name
(GenBank) uroporphyrinogen-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
roc
Romboutsia sp. CE17
Pathway
roc00860
Porphyrin metabolism
roc01100
Metabolic pathways
roc01110
Biosynthesis of secondary metabolites
roc01120
Microbial metabolism in diverse environments
roc01240
Biosynthesis of cofactors
Module
roc_M00924
Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:
roc00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
HF520_11945 (cobA)
Enzymes [BR:
roc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
HF520_11945 (cobA)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
HF520_11945 (cobA)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QJA09619
UniProt:
A0A6H1X2D0
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Position
complement(2505861..2507366)
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AA seq
501 aa
AA seq
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MKGKVYLVGAGPGDYKLLTLKGLECIKNADVIVYDRLANSNYLREAKPTCEFIYVGKESS
NHTLPQDDINRVIADKAKEGKIVTRLKGGDPYVFGRGGEEGQLLKEEGIDFEVVPGITSA
IGGLCYAGIPITHRDHASSFHVITGHLREDDKENPEINWNALANTRGTLVFLMGVANLKK
ISENLIKEGKCKDTPVALISWATRYNQRVITSTLEDVYETAIRENVKPPTLIAIGSVVNL
RDTLNFFENKPLFGKNIMVTRSRTQSSSIVEKIMDLGGNPIEIPTIKIEKMENNIELENE
INNIKNYTYLVLTSKNAVEIFFDKLEEMNLDARALANLKVCAIGSATAKEIKSRGINPDI
VPEKFVAESLYDELKDKLTKEDKILIPRAKNARDYLLDKLGEICTVKEVHTYESVIDTSR
KDEILDILDKEELDYITFASSSSVRNFVEIIGEENLEKINSSKVISIGPITSATARELNI
DVYKEAEKATIDKIVEAITVD
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atgaagggtaaagtttacttagtaggtgcaggaccaggagattataagctattaactcta
aaaggacttgagtgtataaagaatgctgatgttatagtttatgatagattagcaaattca
aactatttaagagaagctaagcctacttgtgaatttatatatgtaggtaaagaatctagt
aatcatacacttcctcaagatgatataaatagagtgatagctgataaggctaaagaaggt
aagatagttacaagacttaagggaggagacccttatgtatttggaagaggtggagaagaa
gggcaacttttaaaagaagaaggcatagattttgaagtagttcctggaataacttctgct
ataggtggactttgctatgcaggtattcctataactcacagggaccatgcatcttcattc
cacgtaataacaggtcatctaagagaagatgataaagaaaatcctgagataaactggaac
gctttagctaatactagaggaactcttgtatttttaatgggagtagctaatctaaagaaa
ataagtgaaaatctaatcaaagaaggaaaatgtaaagatactccagttgcacttataagt
tgggcaactaggtataaccaaagagtaataacttctacactagaagatgtttatgaaact
gctataagagaaaatgttaaaccaccaacattaatagcaataggaagtgtagttaattta
agggatactctaaacttctttgaaaataaaccattattcggtaaaaatataatggttact
agaagtagaactcaaagtagttcaatagtagaaaaaataatggatttaggtggaaatcca
atagaaatacctactattaaaatagaaaagatggaaaataatattgagttagaaaatgaa
attaataatataaaaaattatacatatttagttcttacaagtaagaatgctgtagagatt
ttcttcgataagttagaagaaatgaacttagatgctagagctttagcaaatttaaaggta
tgtgcaattggaagtgctacagctaaggaaataaaatctagaggaataaatcctgatata
gttccagaaaagtttgtggcagagtctttatatgatgagttaaaagacaaattaactaaa
gaagataagatattaataccaagggctaagaatgcgagggattatttattagataagtta
ggtgaaatttgtactgtaaaagaagttcatacttatgaaagtgtaatagacactagtagg
aaggatgaaatcttagatatactagataaagaagagttagattatataacttttgcaagt
tcttcaagtgtaagaaattttgtagaaattataggagaagaaaatttagaaaaaataaac
agttcgaaagtaatatctataggaccaataacttcagctactgcaagagaattaaatata
gatgtctataaagaagctgaaaaagctactatagataagattgtagaggcaattactgta
gattag
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