Rhinopithecus roxellana (golden snub-nosed monkey): 104682411
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Entry
104682411 CDS
T03989
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
rro
Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro00010
Glycolysis / Gluconeogenesis
rro00020
Citrate cycle (TCA cycle)
rro00620
Pyruvate metabolism
rro00785
Lipoic acid metabolism
rro01100
Metabolic pathways
rro01200
Carbon metabolism
rro01210
2-Oxocarboxylic acid metabolism
rro04066
HIF-1 signaling pathway
rro04922
Glucagon signaling pathway
rro05230
Central carbon metabolism in cancer
rro05415
Diabetic cardiomyopathy
Module
rro_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
rro00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
104682411 (PDHA1)
00020 Citrate cycle (TCA cycle)
104682411 (PDHA1)
00620 Pyruvate metabolism
104682411 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
104682411 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
104682411 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
104682411 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
104682411 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
104682411 (PDHA1)
Enzymes [BR:
rro01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
104682411 (PDHA1)
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
DUF1117
Motif
Other DBs
NCBI-GeneID:
104682411
NCBI-ProteinID:
XP_010387362
UniProt:
A0A2K6NLY8
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All DBs
Position
7:85164923..85181881
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AA seq
433 aa
AA seq
DB search
MTLSRRAATEAWRLLGHLKETLGHPRRASWAVRSRRCRQCLCFMRKMLAAVSRVLSGASQ
KPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELK
ADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAE
LTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDG
AANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGM
DILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPI
MLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEV
RGANQWIKFKSVS
NT seq
1302 nt
NT seq
+upstream
nt +downstream
nt
atgactctgtcacgtcgcgctgcgactgaggcgtggcgtctgctggggcacctgaaggag
actttgggacacccgcgtcgtgcctcttgggctgtgaggagtcgccgctgccgccagtgc
ctgtgcttcatgaggaagatgctcgccgccgtctcccgcgtgttgtctggcgcttctcag
aagccggcaagcagagtgctggtagcatcccgtaattttgcaaatgatgccacatttgaa
attaagaaatgtgaccttcaccgactggaagaaggccctcctgtcacaacagtgctcacc
agggaggatgggctcaaatactacaggatgatgcagactgtgcgccgaatggagttgaaa
gcagatcagctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcag
gaagcttgctgtgtgggcctggaagccggcatcaaccccacagaccatctcataacagcc
taccgggctcacggctttaccttcacccggggcctttctgtccgagaaattctcgcagag
cttacaggacgaaaaggaggttgtgctaaagggaaaggaggatcgatgcacatgtatgcc
aagaacttctacgggggcaatggcatcgtgggagcgcaggtgcccctgggcgctgggatt
gctctagcctgtaagtataatggaaaagatgaggtctgcctgactttatatggcgatggt
gctgctaaccagggccagatattcgaagcttacaacatggcagctttgtggaaattacct
tgtattttcatctgtgagaataatcgctatggaatgggaacatctgttgagagagcagca
gccagcactgattactacaagagaggcgatttcattcctgggctgagagtggatggaatg
gatatcctgtgcgtccgagaggcgacaaagtttgctgctgcctattgtagatctgggaag
gggcccatcctgatggagctgcagacttatcgttaccacggacacagtatgagtgatcct
ggagtcagttaccgtacacgagaagaaattcaggaagtaagaagtaagagtgaccctatt
atgcttctcaaggacaggatggtgaacagcaatcttgccagtgtggaagaactaaaggaa
attgatgtggaagtgaggaaggagattgaggatgctgcccagtttgccacggccgatcct
gagccacctttggaggagctgggctaccacatctactccagtgacccacctttcgaagtt
cgtggtgccaatcagtggatcaagtttaagtcagtcagttaa
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