Rhodococcus ruber: CS378_00855
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Entry
CS378_00855 CDS
T05142
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
rrz
Rhodococcus ruber
Pathway
rrz00790
Folate biosynthesis
rrz01100
Metabolic pathways
rrz01240
Biosynthesis of cofactors
Module
rrz_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
rrz00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
CS378_00855
Enzymes [BR:
rrz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
CS378_00855
6.3.2.17 tetrahydrofolate synthase
CS378_00855
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
ATQ27411
UniProt:
A0A098BLM2
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Position
186454..187887
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AA seq
477 aa
AA seq
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MSEDRSAAGPATPSPVDLAELTLVEAELDKRWPETKIEPSLTRIAALMDLLGSPQRSYPS
IQIAGTNGKTSVSRMIDALLTRLHRRTGRTTSPHLQLATERISIDGAPVSPRTYVDTYRE
LEPYVAMIDAQSQAAGGPAMSKFEVTTAMAFAAFAEAPVDVAVVEVGLGGTWDATNVVDA
QVAVVTPIGLDHTEYLGPDLATIAGEKAGIIKKAPDDGLVPRDTVAILAQQEPEVMEVLL
RRAVEADAAVAREGAEFQVLARRIAVGGQQLELQGLGGVYTDIFLPLHGEHQARNAALAL
AAVEAFFGAGADRQLDADAVRAAFASVLNPGRLERVRSAPTVFLDAAHNPHGAKALAAAL
ADEFDFRKLVGVVSVMADKDVPGLLDALEPVFDEIVVTHNGSPRAMDVDELSDLAVARFG
DERVVVAPTLPDALETAVAIAEEVAEPGEAVSGAGVVVTGSVVTAGAARTLFGKDPA
NT seq
1434 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgaggaccggtccgcggccggcccggcgacgccgtcgccggtcgacctggccgag
ctgaccctggtcgaggccgaactcgacaagcgctggcccgaaacgaagatcgagccttcg
ctgacccggatcgcggcgctgatggatctgctcggatccccccagcgcagctatccgtcc
atccagatcgccggcacgaacggtaagacgtcggtgagccgcatgatcgacgccctgctg
acccggttgcaccggcgcaccggccgcaccacgagcccgcacctgcagctggccacggag
cggatcagcatcgacggggcgccggtctccccgcgcacctacgtcgacacctatcgcgaa
ctcgagccgtacgtcgcgatgatcgacgcgcagtcgcaggccgcgggcggcccggcgatg
agcaagttcgaggtgaccacggccatggcattcgccgcgttcgccgaggcccccgtcgac
gtcgccgtcgtcgaggtgggactcggtggcacctgggacgccaccaacgtcgtcgacgcg
caggtcgcggtcgtcaccccgatcgggctcgaccacaccgaatacctcggccccgatctc
gcgacgatcgcgggggagaaggccgggatcatcaagaaggcacccgacgacgggctcgtg
ccccgcgacaccgtcgcaatcctggcccagcaggaacccgaggtgatggaggtgctgctg
cgccgggccgtcgaagcggacgccgccgtcgcacgcgaaggcgccgagttccaggtcctg
gcccggcgcatcgccgtgggcgggcagcaactcgagctgcaaggcctcggcggggtgtac
accgacatcttcctgccgctgcacggcgagcaccaggcccgtaacgccgcgctcgcgctc
gccgccgtggaggcgttcttcggggccggcgccgaccggcagctcgacgccgacgcggtg
cgcgcggcgttcgcctcggtgctcaacccgggccggctcgaacgggtgcgtagcgctccg
acggtgttcctcgacgccgcccacaacccccacggggcgaaggctctcgctgcggccctc
gccgacgagttcgacttccgcaagctggtcggagtggtgtcggtgatggccgacaaggac
gtgcccggtctgctcgacgccctcgagccggtgttcgacgagatcgtcgtgacccacaac
ggctcgccgcgggcgatggacgtcgacgagctctcagacctggccgtggcgcggttcggc
gacgaacgcgtggtcgtcgcgccgacactgcccgacgccctcgagaccgccgtcgccatc
gccgaggaggtcgccgagccgggtgaggcagtatcgggggcgggtgtcgtggtcaccggc
tcggtggtgaccgccggcgccgcccgcactctcttcggaaaggaccccgcgtga
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