Rhipicephalus sanguineus (brown dog tick): 119374040
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Entry
119374040 CDS
T07382
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform X1
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
rsan
Rhipicephalus sanguineus (brown dog tick)
Pathway
rsan00280
Valine, leucine and isoleucine degradation
rsan00640
Propanoate metabolism
rsan00785
Lipoic acid metabolism
rsan01100
Metabolic pathways
rsan01210
2-Oxocarboxylic acid metabolism
Module
rsan_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
rsan00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
119374040
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
119374040
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
119374040
Enzymes [BR:
rsan01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
119374040
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
Transketolase_N
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
119374040
NCBI-ProteinID:
XP_037500027
EnsemblRapid:
LOC119374040
LinkDB
All DBs
Position
11:34882401..34908556
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AA seq
445 aa
AA seq
DB search
MLSTTMYGRLTSAVRLGFLRPKMPHRVLAAIEARPLVTEAETGSFQPPTPLSRRMPTTTK
MEFVPANAFDGIPMYSILNRSGKLADGVEEPKLDKDLLVRMYSKMVQMNIIDQIMYESQR
QGRISFYMTHYGEEGVLIGSAAALDDKDLVFVQYREYGVLLWRNFTVNQTMQQCYSTMYD
YGKGRQMPIHYGSTEEHFVTVSSTLATQMPQAAVGTAYAYKLAQKKQCVACYFGDGAASE
GDAHASFNFAGVLGTPIIFICRNNGYAISTPTHEQYSCDGIAARGPSYGLTTIRVDGQDI
LAMYMAVQEARRFVMEQQKPILIEAMTYRIGHHSTSDDSTAYRSVDEVRTWDEHAHPITR
LRQFLLDRGYWSEQQDKDIKAAFKKEVLQNIKEVEKIPKPPVSDLFTDVYKDMPAHLKEQ
MTYMLNHVQHYKDGYPVDLFAKERS
NT seq
1338 nt
NT seq
+upstream
nt +downstream
nt
atgttgtccacgacgatgtacggacgtctcacgtcagccgtcaggctgggatttctgcga
cccaagatgccacatcgcgtgcttgcggccatcgaagcaaggccgcttgtgaccgaggcg
gagacgggcagtttccagccacccactccgttgagccgacggatgccgaccaccaccaag
atggagttcgtgccagcaaatgccttcgatggcattcccatgtacagcatcctgaacagg
agtggcaaactggccgacggtgtcgaagaacccaagctggacaaggacctgctggtgcgt
atgtactccaagatggtgcagatgaacatcatcgaccagatcatgtacgagtcacagagg
cagggccgtatctccttctacatgacccactacggcgaggagggcgtgctcatcggaagc
gcagctgcgctcgacgacaaggacctcgtctttgtccagtaccgcgagtacggtgtgctt
ctctggcgaaactttactgtgaaccagacgatgcagcagtgttactccacgatgtatgac
tatggcaagggccgccagatgcctattcactatggctcgactgaggagcactttgtcacc
gtctcgtcaacccttgcaacacagatgccgcaggcagcagtgggaacagcatatgcctac
aagctcgcccagaagaagcaatgcgtggcctgctactttggtgatggagcggccagtgag
ggtgatgcccatgcctccttcaactttgctggcgtcctcggcacacccatcattttcatc
tgtcggaacaatggttacgccatctcaacgccaacccacgagcagtacagctgtgatgga
attgctgcacggggtccttcatacgggttgacaacgattcgtgtggacggtcaggacatt
ctcgccatgtacatggcagtacaggaggcccgccgctttgtgatggagcagcagaagcca
atcctcattgaagcgatgacgtacagaattggccaccacagcacgtcggacgacagcaca
gcctatcgttcggtggatgaagtgcggacgtgggacgagcatgcccatccaatcacgcgg
cttcgccagttcctcctcgatcgtggctactggagtgaacagcaggataaggacatcaag
gcagcattcaagaaagaggtcttacagaacatcaaagaagtcgaaaaaattcccaagccg
ccagtcagcgacctcttcaccgatgtttacaaggacatgccggcgcatctcaaggaacag
atgacgtacatgctgaaccacgtacagcactacaaagatggttaccccgtcgacttgttt
gccaaagagaggagctag
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