Rissa tridactyla (black-legged kittiwake): 128906625
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Entry
128906625 CDS
T09443
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
rtd
Rissa tridactyla (black-legged kittiwake)
Pathway
rtd00270
Cysteine and methionine metabolism
rtd00480
Glutathione metabolism
rtd01100
Metabolic pathways
rtd01240
Biosynthesis of cofactors
rtd04216
Ferroptosis
Module
rtd_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
rtd00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
128906625 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
128906625 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
128906625 (GCLC)
Enzymes [BR:
rtd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
128906625 (GCLC)
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GFIT
Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
128906625
NCBI-ProteinID:
XP_054050100
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Position
3:101043206..101080402
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AA seq
694 aa
AA seq
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MGLLSQGSPLSWEETRRHAEHVRRHGIIQFLHIYRALRDRHKDVLKWGDEACSMCVWIYS
FRSATLLAQLCSFPWEKLGSCLSSSSALQHVMDGGQRCVGFAAEGEHQVEYMLVKFDHEN
KKVRLVLCGEEVLQTLQDKGEKVNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTVQD
NMRKRRQEAASVLKENEAVCTVTSFPRLGCPGFTLPEYKPTPVEGGASKSLFFPDEAINK
HPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPNDDGEAAKAAKPDYIYMDAM
GFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVIS
ASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTIDKDIYEHLIKE
GIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDIG
WRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVRQ
GMFYFRKDICKGGNAVVDGCGSAQNGTGTDAEEYTLMSIDTIINGKEGVFPGLIPILNSY
LENMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFIAQHPDYKQDSVITDEMNYSL
IWKCNQIAQGQAECPELLGVGFNKKQSGNKTGSL
NT seq
2085 nt
NT seq
+upstream
nt +downstream
nt
atggggttgctgtcgcagggctcgccgctgagctgggaggagacgcggcggcacgccgag
cacgtgcggaggcacggcatcatccagttcctccacatctaccgcgccctgcgcgaccgc
cacaaggacgtcctcaagtggggcgatgaggcttgctctatgtgtgtgtggatttacagc
tttcgctctgcaaccttgctggcccaactgtgttcctttccctgggagaagctgggaagc
tgcctttcatcctcatcagccttgcagcacgtgatggatggaggacagagatgtgtaggg
tttgctgcggagggagagcaccaggtggaatatatgttagtaaaatttgaccacgagaat
aagaaagtgcgcttggtgctctgtggtgaagaagttcttcaaacgctacaagacaagggg
gagaaggtaaaccccaaccacccaacactctggcgaccagaatatggaagctacatgatt
gaagggacgcctgggcagccatatgggggaaccatgtctgaattcaacactgtgcaagac
aacatgaggaaaagacggcaagaggccgcttctgtgctcaaagaaaacgaggctgtttgc
actgtgacatcatttccaaggttagggtgtcctgggtttacgctgccggaatataagcca
acgccagtagaaggaggagcttcgaaatccctcttttttccagatgaagccatcaataaa
catcctagatttagtacactgaccagaaacattcgtcaccgaagaggagaaaaggttgtg
ataaatgtaccaatatttaaagacaagaacacgccatcaccatttatcgaaacgtttcct
aatgacgatggagaagcagcaaaagcagcaaagccggactatatatacatggatgctatg
ggttttggaatgggaaactgttgtcttcaggtaacattccaggcgtgcagcatttctgaa
gcaaggtatctctatgatcagctggccacgatctgtcccattgtgatggcgttgagtgct
gcatctccgttctacagaggctacgtgtctgacattgactgtcgctggggagtgatctct
gcatctgtagatgatcgaacgcgagaagagagggggctagagccactgaagaacaaccat
tatagaatcagtaaatccagatatgattccatagacagttatctatctgaatgtggtgag
aaatacaatgacattgatttgacaatagacaaagatatctacgagcacctaataaaggaa
ggtattgaccaccttttggcacagcatattgcacacttgttcattcgagacccattgact
ttgtttgaggagaaaatacatctagatgatgcaaatgaatccgaccattttgagaatatt
caatctacaaattggcagacaatgaggtttaagccacctcctccaaattcagacattgga
tggagagtggaattcagacctatggaggtccagttaacagactttgaaaattctgcgtat
gttgtgttcgtcgtattgctaaccagagtgattctgtcatataaactggattttctcatt
ccgttgtctaaggtggatgaaaacatgaaggtggcccagaaaagagatgctgtgcggcag
ggaatgttttacttcagaaaagatatttgcaaaggtggaaacgctgttgtggatggctgt
ggctctgcacagaacgggacaggcacagacgcagaagagtacaccttaatgagcattgat
acaattatcaatgggaaggaaggagtctttcctggtttgatcccaattttgaattcctat
cttgaaaacatggaagtggatgtggacacaaggtgcaccatcctaaactacctgaagtta
ataaaaaagagagcatctggagagttaatgacagttgctcgatggatgagggaatttatc
gcgcagcatccagactacaagcaagacagcgtgataactgatgaaatgaattacagcctt
atttggaaatgcaaccaaatcgcacaaggccaggcagagtgtcctgaactattaggggtg
ggatttaataagaaacaaagtggaaacaaaactggctctttgtaa
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