Staphylococcus aureus subsp. aureus USA300_FPR3757 (CA-MRSA): SAUSA300_0993
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Entry
SAUSA300_0993 CDS
T00323
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase E1 component, alpha subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
saa
Staphylococcus aureus subsp. aureus USA300_FPR3757 (CA-MRSA)
Pathway
saa00010
Glycolysis / Gluconeogenesis
saa00020
Citrate cycle (TCA cycle)
saa00620
Pyruvate metabolism
saa00785
Lipoic acid metabolism
saa01100
Metabolic pathways
saa01110
Biosynthesis of secondary metabolites
saa01120
Microbial metabolism in diverse environments
saa01200
Carbon metabolism
saa01210
2-Oxocarboxylic acid metabolism
Module
saa_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
saa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SAUSA300_0993 (pdhA)
00020 Citrate cycle (TCA cycle)
SAUSA300_0993 (pdhA)
00620 Pyruvate metabolism
SAUSA300_0993 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SAUSA300_0993 (pdhA)
Enzymes [BR:
saa01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SAUSA300_0993 (pdhA)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
ABD21242
UniProt:
A0A0H2XHD5
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All DBs
Position
1088532..1089644
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AA seq
370 aa
AA seq
DB search
MAPKLQAQFDAVKVLNDTQSKFEMVQILDENGNVVNEDLVPDLTDEQLVELMERMVWTRI
LDQRSISLNRQGRLGFYAPTAGQEASQLASQYALEKEDYILPGYRDVPQIIWHGLPLTEA
FLFSRGHFKGNQFPEGVNALSPQIIIGAQYIQAAGVAFALKKRGKNAVAITYTGDGGSSQ
GDFYEGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDA
LAVYQATKEARDRAVAGEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWEKKDPLVR
FRKFLENKGLWNEDKENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYEDMPQNLAEQ
YEIYKEKESK
NT seq
1113 nt
NT seq
+upstream
nt +downstream
nt
atggctcctaagttacaagcccaattcgatgcagtaaaagttttaaatgatactcaatcg
aaatttgaaatggttcaaattttggatgagaatggtaacgtcgtaaatgaagacttagta
cctgatcttacggatgaacaattagtggaattaatggaaagaatggtatggactcgtatc
cttgatcaacgttctatctcattaaacagacaaggacgtttaggtttctatgcaccaact
gctggtcaagaagcatcacaattagcgtcacaatacgctttagaaaaagaagattacatt
ttaccgggatacagagatgttcctcaaattatttggcatggtttaccattaactgaagct
ttcttattctcaagaggtcacttcaaaggaaatcaattccctgaaggcgttaatgcatta
agcccacaaattattatcggtgcacaatacattcaagctgctggtgttgcatttgcactt
aaaaaacgtggtaaaaatgcagttgcaatcacttacactggtgacggtggttcttcacaa
ggtgatttctacgaaggtattaactttgcagcagcttataaagcacctgcaattttcgtt
attcaaaacaataactatgcaatttcaacaccaagaagcaagcaaactgctgctgaaaca
ttagctcaaaaagcaattgctgtaggtattcctggtatccaagttgatggtatggatgcg
ttagctgtatatcaagcaactaaagaagcacgtgaccgcgcagttgcaggtgaaggtcca
acattaattgaaactatgacatatcgttatggtcctcatacaatggctggtgacgatcca
actcgttacagaacttcagacgaagatgctgaatgggagaaaaaagacccattagtacgt
ttccgtaaattccttgaaaacaaaggtttatggaatgaagacaaagaaaatgaagttatt
gaacgtgcaaaagctgatattaaagcagcaattaaagaggctgataacactgaaaaacaa
actgttacttctctaatggaaattatgtatgaagatatgcctcaaaacttagcagaacaa
tatgaaatttacaaagagaaggagtcgaagtaa
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