Saccharopolyspora sp. ASAGF58: FDZ84_18740
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Entry
FDZ84_18740 CDS
T06538
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sacg
Saccharopolyspora sp. ASAGF58
Pathway
sacg00790
Folate biosynthesis
sacg01100
Metabolic pathways
sacg01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sacg00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
FDZ84_18740
Enzymes [BR:
sacg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
FDZ84_18740
6.3.2.17 tetrahydrofolate synthase
FDZ84_18740
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
GlnR_1st
Motif
Other DBs
NCBI-ProteinID:
QIZ36340
UniProt:
A0A6H1R895
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Position
3926887..3928254
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AA seq
455 aa
AA seq
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MSGTDPAALQELRVVEAELNERWPETKIEPSLDRIRALTELLADPQHSYPVVHIAGTNGK
SSTSRITDALLSGLGLRTGRYTSPHLQLATERISIDGAPISPEGYVEAYRDVAPYVSIVD
SRSDVRMSKFEVLTGMAFAAFADAPVEAAVIEVGLGGSWDATNVADAKIAVVCPVALDHA
EYLGTDLAGIAEEKAGIIKPGSIAVVAAQPAEAQKAIMERVAEVDATVAREGQEFGVLSR
TVAVGGQLLRLQGLGGVYDEIFLPLHGEHQARNAALALAAVEAFFGAGADRQLDVERVRE
AFAGVVTPGRLERVRAAPTVLVDAAHNPHGARALADALSSEFSFRRLVAVVGVLGDKDAR
GILAELEPVVEEIVLTKNSSPRAMDPDELAGVAKDIFGPDRIVVEPRLDNAVETAIQLAE
ETEEPGESVSGGGVVITGSVVTAGEARALFGKEPA
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
ttgtccggcaccgatcccgccgcgctgcaggaactacgcgtggtggaggccgagctcaac
gaacgctggccggaaaccaagatcgaaccgtcgctcgaccggatcagggcgctcaccgag
ctgctcgccgacccgcagcacagctatccggtcgtgcacatcgccggcaccaacggcaag
tcgtcgacctcgcgcatcacggacgcgctgctgagcggcctcgggctgcgcaccggccgt
tacaccagcccgcatctgcagctggccaccgagcgcatcagcatcgacggcgcgcccatc
agccccgagggctacgtcgaggcgtaccgggacgtcgccccgtatgtgtccatcgtggac
tcgcgcagcgacgtccggatgagcaagttcgaggtgctcaccggcatggcgttcgcggcc
ttcgccgatgccccggtggaagccgcggtgatcgaggtcgggctgggcggaagctgggac
gcgaccaacgtcgccgacgcgaagatcgcggtcgtctgcccggtcgcgcttgaccacgcc
gagtacctcggcaccgacctggccgggattgccgaggagaaggccgggatcatcaagccc
ggttcgatcgccgtcgtggcggcgcagcccgccgaggcgcagaaggcgatcatggagcgg
gtcgccgaggtggacgcgaccgtggcccgtgaaggccaggagttcggggtgctgtcccgg
accgtcgcggtgggcggccaactgctccggctgcaaggcctgggcggcgtgtacgacgag
atcttcctgccgctgcacggcgaacaccaggcgcgcaacgccgcgctcgcgctagcggcc
gtcgaggcgttcttcggtgccggtgcggaccggcagctcgacgtcgagcgggtccgcgaa
gccttcgccggcgtcgtcaccccgggacgcctggagcgggtccgcgcggcaccgaccgtg
ctcgtcgacgcggcccacaacccgcacggtgctcgcgccctcgccgacgcactgagctcg
gagttctccttccgccgactggtcgccgtggtcggcgtgctcggcgacaaggacgcgcgc
ggcatcctcgccgaactggaaccggtggtcgaggagatcgtgttgaccaagaactcctcg
ccccgcgcgatggatcccgacgaactcgcgggcgtggccaaggacatcttcggaccagac
cggatcgtggtggaaccccggctggacaacgcggtcgagaccgcgatccagctggccgag
gagaccgaggaaccgggcgagtcggtctccggcggcggcgtggtgatcaccgggtccgtg
gtgaccgcgggcgaggcgcgcgccctgttcggcaaggagccggcgtga
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