Streptococcus alactolyticus: O6R09_03570
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Entry
O6R09_03570 CDS
T08982
Name
(GenBank) thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
sacy
Streptococcus alactolyticus
Pathway
sacy00010
Glycolysis / Gluconeogenesis
sacy00020
Citrate cycle (TCA cycle)
sacy00620
Pyruvate metabolism
sacy00785
Lipoic acid metabolism
sacy01100
Metabolic pathways
sacy01110
Biosynthesis of secondary metabolites
sacy01120
Microbial metabolism in diverse environments
sacy01200
Carbon metabolism
sacy01210
2-Oxocarboxylic acid metabolism
Module
sacy_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sacy00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
O6R09_03570
00020 Citrate cycle (TCA cycle)
O6R09_03570
00620 Pyruvate metabolism
O6R09_03570
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
O6R09_03570
Enzymes [BR:
sacy01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
O6R09_03570
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Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
DUF1194
Motif
Other DBs
NCBI-ProteinID:
WBB07013
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Position
680629..681594
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AA seq
321 aa
AA seq
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MNLSRENYIEMYLKMQRIREFDLRINKLVRRGFVQGMTHFSVGEEAASVGAMAHLTYDDI
IFSNHRGHGQCIAKDMDLNKMMAELAGKVNGVSKGRGGSMHLADFEKGNYGTNGIVGGGY
ALAVGAALTQDYKQTGNIVVAFSGDGATNEGSFHESVNLAATWHLPVIFFIINNRYGISM
DITKATNTPHLYTRAEAYGIPGFYCENGNDVLAVYDTMGKAVAHVRAGKGPAIVEVESYR
WFGHSTADAGKYRSKEEVDEWKKKDPLVLFRTYLTDNHLVDAEALDALDAQVVKEIDDAY
AFAQNSPEPDLAVAFEDVWAD
NT seq
966 nt
NT seq
+upstream
nt +downstream
nt
atgaatttgtcacgtgaaaactatatagagatgtatctaaaaatgcagcgcattcgtgag
tttgacctgcgcatcaataaactcgtccgccgaggctttgtgcaaggcatgacgcatttt
tctgtgggggaagaagcagctagtgttggggctatggctcacttgacctatgatgatatt
attttttcaaatcaccgtgggcatgggcagtgtattgccaaggacatggatttgaataaa
atgatggccgaattggcaggcaaggtgaatggggtatctaaaggtcgtgggggctcgatg
cacctagcggattttgaaaaaggcaattacggtaccaatggtattgtagggggtggctat
gccctagctgttggtgctgccctgacacaagactacaagcaaacaggcaatattgtcgtg
gctttttcgggtgatggagcaaccaacgaagggtctttccatgaatccgtgaacctagct
gccacatggcacttgccagtgattttctttatcatcaataaccgttacggtatttcgatg
gacatcacaaaagcaaccaacacccctcacctttacacgcgtgcggaagcttacggcatt
ccaggtttttactgtgaaaatggcaatgatgtgttggcggtttacgacacgatgggcaag
gcggttgcgcatgtgcgtgctggtaagggaccagccatcgtggaagtagaatcttaccgc
tggtttgggcattcaacggccgatgctggaaaataccgcagcaaggaagaagtcgatgag
tggaagaaaaaagacccgctggtcctctttcgcacctatttgacggacaatcacttggtt
gacgctgaagcattggatgctttggatgctcaagtggtcaaagaaatcgatgacgcttac
gcttttgctcaaaatagccctgagccagatttagcagtggcatttgaagatgtttgggct
gactag
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