Staphylococcus aureus subsp. aureus Newman: NWMN_0959
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Entry
NWMN_0959 CDS
T00557
Symbol
phdA
Name
(GenBank) pyruvate dehydrogenase E1 component, alpha subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
sae
Staphylococcus aureus subsp. aureus Newman
Pathway
sae00010
Glycolysis / Gluconeogenesis
sae00020
Citrate cycle (TCA cycle)
sae00620
Pyruvate metabolism
sae00785
Lipoic acid metabolism
sae01100
Metabolic pathways
sae01110
Biosynthesis of secondary metabolites
sae01120
Microbial metabolism in diverse environments
sae01200
Carbon metabolism
sae01210
2-Oxocarboxylic acid metabolism
Module
sae_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sae00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
NWMN_0959 (phdA)
00020 Citrate cycle (TCA cycle)
NWMN_0959 (phdA)
00620 Pyruvate metabolism
NWMN_0959 (phdA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
NWMN_0959 (phdA)
Enzymes [BR:
sae01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
NWMN_0959 (phdA)
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
BAF67231
UniProt:
A0A0H3K7D7
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All DBs
Position
1065117..1066229
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AA seq
370 aa
AA seq
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MAPKLQAQFDAVKVLNDTQSKFEMVQILDENGNVVNEDLVPDLTDEQLVELMERMVWTRI
LDQRSISLNRQGRLGFYAPTAGQEASQLASQYALEKEDYILPGYRDVPQIIWHGLPLTEA
FLFSRGHFKGNQFPEGVNALSPQIIIGAQYIQAAGVAFALKKRGKNAVAITYTGDGGSSQ
GDFYEGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDA
LAVYQATKEARDRAVAGEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWEKKDPLVR
FRKFLENKGLWNEDKENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYEDMPQNLAEQ
YEIYKEKESK
NT seq
1113 nt
NT seq
+upstream
nt +downstream
nt
atggctcctaagttacaagcccaattcgatgcagtaaaagttttaaatgatactcaatcg
aaatttgaaatggttcaaattttggatgagaatggtaacgtcgtaaatgaagacttagta
cctgatcttacggatgaacaattagtggaattaatggaaagaatggtatggactcgtatc
cttgatcaacgttctatctcattaaacagacaaggacgtttaggtttctatgcaccaact
gctggtcaagaagcatcacaattagcgtcacaatacgctttagaaaaagaagattacatt
ttaccgggatacagagatgttcctcaaattatttggcatggtttaccattaactgaagct
ttcttattctcaagaggtcacttcaaaggaaatcaattccctgaaggcgttaatgcatta
agcccacaaattattatcggtgcacaatacattcaagctgctggtgttgcatttgcactt
aaaaaacgtggtaaaaatgcagttgcaatcacttacactggtgacggtggttcttcacaa
ggtgatttctacgaaggtattaactttgcagcagcttataaagcacctgcaattttcgtt
attcaaaacaataactatgcaatttcaacaccaagaagcaagcaaactgctgctgaaaca
ttagctcaaaaagcaattgctgtaggtattcctggtatccaagttgatggtatggatgcg
ttagctgtatatcaagcaactaaagaagcacgtgaccgcgcagttgcaggtgaaggtcca
acattaattgaaactatgacatatcgttatggtcctcatacaatggctggtgacgatcca
actcgttacagaacttcagacgaagatgctgaatgggagaaaaaagacccattagtacgt
ttccgtaaattccttgaaaacaaaggtttatggaatgaagacaaagaaaatgaagttatt
gaacgtgcaaaagctgatattaaagcagcaattaaagaggctgataacactgaaaaacaa
actgttacttctctaatggaaattatgtatgaagatatgcctcaaaacttagcagaacaa
tatgaaatttacaaagagaaggagtcgaagtaa
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