Streptomyces noursei NK660: DC74_2676
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Entry
DC74_2676 CDS
T03082
Name
(GenBank) 2-oxoacid dehydrogenase subunit E1
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
salu
Streptomyces noursei NK660
Pathway
salu00010
Glycolysis / Gluconeogenesis
salu00020
Citrate cycle (TCA cycle)
salu00620
Pyruvate metabolism
salu00785
Lipoic acid metabolism
salu01100
Metabolic pathways
salu01110
Biosynthesis of secondary metabolites
salu01120
Microbial metabolism in diverse environments
salu01200
Carbon metabolism
salu01210
2-Oxocarboxylic acid metabolism
Module
salu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
salu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
DC74_2676
00020 Citrate cycle (TCA cycle)
DC74_2676
00620 Pyruvate metabolism
DC74_2676
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DC74_2676
Enzymes [BR:
salu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
DC74_2676
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
AIA03178
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Position
3037778..3040453
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AA seq
891 aa
AA seq
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MPDPVRLPYSQLDQLPDRDPEETAEWRESLDAVAKAAGPHRAAYLMRRALEHTARTEGTD
LPSLLETDYVNTIPTSAEPAFPGDEALEARITAWNRWNAAAMVTRGSKLGLGGHIATFAS
AAWLYETGFQHFFRGKEGDGSGDQLYIQGHASPGIYARAFLEGRLTEEQLDHFRQEAGGE
GLPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLEHRDIKDTSNSHVWAFLGDGE
MDEPESTAALALAGREGLDNLTFVINCNLQRLDGPVRPNFKIVQELEAQFRAAGWNVVKA
LWGQAWDEIFALDADGAVIQRLRETPDAQFQTYATRDAAYLREHFFGASDALKAIGAQLS
DAKLLELFQTSRAGHEPRKVYAAYKAAAEQKGAPTVILAQTVKGYTLGTGFESRNANHQM
KKLTMAEFRTMRDLLELPIPDSALEGDTVPYWRPAEDSPEMQYLRTRRAALDGPAPARKV
AAKPLPMPADKNFDALKKGSGSQEIATTMAFVRLIKDLMRDKETGKRWVPIVPDEARTFG
MESLFPTAGLYSPKGATYDPVDRDQLLWYKEAKNGQILNEGITEAGSLADFTAAATSYAT
HGEPMIPFYIFYSMFGWQRTADQFWALADQLGRGFVIGATAGRTTMTGEGLQHADGHSHL
IASTNPAALSYDPAFAYEVAVIVKEGLRRMYGPDAEDVFYYLTVYNETKVQPAMPEGVEE
DILKGLYRFKEATTIEGAEVPRLQLLASGTAIHWILEAQQLLAADWGVAADVWSAPSWTE
LRRDALECDAARLEGEDRVPHVTRALAGAPGPVVAVSDWMRAVPDQIAPWVEQDWTSIGT
DGFGLSDTRDAARRHFGVDPQSVVVQALAALARRGDVKPETVKEARERYGL
NT seq
2676 nt
NT seq
+upstream
nt +downstream
nt
atgcccgaccccgtgcgcctgccgtacagccagctcgaccagctcccggaccgcgacccc
gaggagacggccgagtggcgcgagtcgctggacgccgtcgccaaggcagcgggcccgcat
cgcgccgcatacctgatgcgccgcgccctggagcacaccgcccgcaccgaaggcaccgac
ctgccgtcgctgctggagacggactacgtcaacaccatcccgacctccgccgagcccgcg
ttcccgggtgacgaggcgctggaggcccggatcaccgcctggaaccgctggaacgcggcg
gccatggtcacccgcggctccaagctgggcctcggcggccacatcgccaccttcgcctcg
gcggcctggctctacgagaccggcttccagcacttcttccgcggcaaggagggcgacggc
tccggcgaccagctctacatccagggccacgcctcccccggcatctacgcccgcgccttc
ctggaaggccggctgacggaggagcagctcgaccacttccgccaggaggccggcggcgag
ggcctgccctcgtacccgcacccgcggcggctgccctggctgtgggagttccccaccgtc
tcgatgggcctcggcccgctgtccgcgatctaccaggcgcgcttcaaccgctacctggag
caccgcgacatcaaggacaccagcaactcgcacgtctgggccttcctgggcgacggcgag
atggacgagccggagtcgaccgcggcactggcgctggccggccgcgagggcctggacaac
ctgaccttcgtcatcaactgcaacctgcagcgcctcgacggtccggtccgcccgaacttc
aagatcgtgcaggagctggaggcccagttccgcgccgccggttggaacgtcgtcaaggcc
ctgtggggccaggcgtgggacgagatcttcgccctcgacgccgacggcgcggtcatccag
cgcctgcgcgagacccccgacgcgcagttccagacgtacgccacccgcgacgccgcctac
ctgcgcgagcacttcttcggcgccagcgacgccctcaaggcgatcggcgcgcagctctcc
gacgcgaagctgctggagctgttccagacctcccgcgccggccacgagccgcgcaaggtg
tacgccgcgtacaaggccgccgccgagcagaagggcgcgccgacggtgatcctggcgcag
accgtcaagggctacaccctcggcacgggcttcgagtcccgcaacgccaaccaccagatg
aagaagctgacgatggcggagttccgcaccatgcgggacctgctcgaactccccatcccg
gacagcgcgctggaaggcgacacggtgccgtactggcgcccggccgaggactcgccggag
atgcagtacctgcgcacccggcgcgccgccctcgacggcccggccccggcccgcaaggtc
gcggccaagccgctgccgatgcccgccgacaagaacttcgacgcgctgaagaagggctcc
ggcagccaggagatcgccaccaccatggcgttcgtccggctgatcaaggacctgatgcgg
gacaaggagaccggcaagcgctgggtcccgatcgtcccggacgaggcccgcaccttcggc
atggagtcgctcttcccgaccgccggcctctactcccccaagggcgcgacctacgacccg
gtcgaccgggaccagctgctctggtacaaggaggccaagaacggccagatcctcaacgag
ggcatcaccgaggccggttcgctggccgacttcaccgccgccgcgacgtcgtacgcgacg
cacggcgagccgatgatcccgttctacatcttctactcgatgttcggctggcagcggacc
gccgaccagttctgggcgctcgccgaccagctgggccgcggcttcgtgatcggcgccacc
gccggccgcacgacgatgaccggtgagggcctccagcacgccgacggccactcgcacctg
atcgcctcgaccaacccggcggcgctgtcgtacgacccggcgttcgcctacgaggtggcg
gtgatcgtcaaggagggtctgcgccggatgtacggtccggacgccgaggacgtcttctac
tacctgacggtctacaacgagaccaaggtgcagccggcgatgccggagggcgtcgaggag
gacatcctcaagggcctctaccgcttcaaggaggccaccaccatcgagggcgccgaggtc
ccgcggctccagctgctggcctccggcaccgcgatccactggatcctggaggcgcagcaa
ctgctcgccgccgactggggcgtggcggcggacgtgtggtccgcgccgtcctggacggag
ctccgccgggacgccctggagtgcgacgcggcccgcctggagggcgaggaccgggttccg
cacgtcacccgtgcgctggccggtgcgcccggcccggtcgtcgcggtgagcgactggatg
cgggcggtaccggaccagatcgccccgtgggtggagcaggactggacctccatcgggacg
gacggcttcggcctgtccgacacccgtgacgcggcccgccgccacttcggcgtcgacccg
cagtcggtggtcgtccaggcactggcggccctcgcccggcgtggggacgtcaagccggag
acggtcaaggaggcccgcgagcgctacgggctgtga
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