Streptomyces alboniger: CP975_11825
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Entry
CP975_11825 CDS
T06908
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
salw
Streptomyces alboniger
Pathway
salw00790
Folate biosynthesis
salw01100
Metabolic pathways
salw01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
salw00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
CP975_11825
Enzymes [BR:
salw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
CP975_11825
6.3.2.17 tetrahydrofolate synthase
CP975_11825
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QEV22265
UniProt:
A0A5J6I036
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Position
complement(2678202..2679725)
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AA seq
507 aa
AA seq
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MSDLPPNDEHADRPADDEAFEEIVGAETDRDPDLAVIEAGSRTLRTLAGPPQGDIPARPT
DPEVDKALREVETELAGRWGETKLEPSVSRIAALMDVLGEPQRAYPSIHITGTNGKTSTA
RMIEALFSAFELRTGRYTSPHVQSITERISLDGAPIEAERFVETYNDIKPYVEMVDAQQE
YRLSFFEVLTGMAYAAFADAPVDVAVVEVGMGGSWDATNVIDGSVAVITPIDLDHTDRLG
STTGEIAAEKAGIIKPDATVIMAQQPVDAAQVLLKKAVEVDATVAREGLEFGVVARRVAV
GGQLLTLRGLGGEYEEVFLPLHGEHQAHNAAVALAAVEAFFGIGSQHARPLDIDTIRKAF
ATVSSPGRLEVVRRSPTVVLDAAHNPAGARATAAAISEVFDFSNLVGVVGASDGKDMRGL
LEAFEPIFAEVVITQNTSHRAMDADELAAIAVEVFGDDRVQVEPRLPDALEAAITLAEEE
GEFAGGGVLVTGSVITVGEARLLLGRG
NT seq
1524 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgacctccccccgaacgacgagcacgccgaccgccccgccgacgacgaggccttc
gaggagatcgtcggcgccgagaccgacagggaccccgacctcgccgtcatcgaggcgggc
agccgcaccctgcgcaccctggcgggcccgccgcagggcgacatccccgcccggcccacc
gacccggaggtggacaaggcgctgcgcgaggtcgagacggagctggcgggccgctggggc
gagacgaagctggagccctccgtcagccgcatcgccgcgctgatggacgtcctgggcgag
ccccagcgcgcgtacccctcgatccacatcacggggacgaacggcaagacgtccacggcc
cgcatgatcgaggccctgttctccgccttcgagctgcgcaccgggcggtacacctcgccc
cacgtccagtcgatcaccgagcggatcagcctggacggcgcccccatcgaggccgagcgc
tttgtggagacgtacaacgacatcaagccgtacgtggagatggtcgacgcccagcaggag
tacaggctctccttcttcgaggtcctcaccggcatggcgtacgcggccttcgcggacgcc
cccgtggacgtggccgtcgtcgaggtcggcatgggcggcagctgggacgcgacgaacgtg
atcgacggctccgtcgccgtcatcacccccatcgacctggaccacacggaccgcctgggc
tccaccaccggagagatcgccgcggagaaggccggcatcatcaagccggacgccacggtg
atcatggcccagcagccggtggacgcggcccaggtgctcctgaagaaggccgtcgaggtc
gacgccacggtcgcccgcgagggcctggagttcggcgtcgtcgcccgccgggtcgcggtc
ggcggccagctcctgacgctccgcggcctgggtggggagtacgaggaagtcttcctgccc
ctgcacggcgagcaccaggcgcacaacgccgcggtggcgctcgccgccgtcgaggcgttc
ttcggcatcggctcgcagcacgcccgcccgctggacatcgacaccatccgcaaggcgttc
gccacggtctcctcgccgggccgcctggaggtcgtacgccgctcgcccaccgtcgtcctg
gacgccgcgcacaaccccgcgggcgcccgcgccaccgccgccgccatcagcgaggtcttc
gacttcagcaatctcgtcggcgtggtcggcgcgagcgacggcaaggacatgcggggcctc
cttgaggccttcgaaccgatcttcgccgaggtcgtcatcacgcagaacaccagccaccgc
gcgatggacgccgacgagctggccgcgatcgccgtcgaggtcttcggcgacgaccgcgtc
caggtcgagccgcgtctgcccgacgcgctggaggccgcgatcaccctcgccgaggaagag
ggcgagttcgcgggcggcggcgtcctggtcaccggttccgtcatcacggtcggcgaggcc
cggctgctcctggggaggggctga
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