Streptomyces aquilus: EJC51_17225
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Entry
EJC51_17225 CDS
T07011
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
saqu
Streptomyces aquilus
Pathway
saqu00790
Folate biosynthesis
saqu01100
Metabolic pathways
saqu01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
saqu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
EJC51_17225
Enzymes [BR:
saqu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
EJC51_17225
6.3.2.17 tetrahydrofolate synthase
EJC51_17225
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AZP17694
UniProt:
A0A3S9HZZ9
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Position
complement(3754931..3756418)
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AA seq
495 aa
AA seq
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MSDSDDPFDEIISAETDRDPDLAVIEAGSRTLRTQGTPPEAQVPTRPEDPELDKALRDVE
AELATRWGETKLEPSVSRIAALMDVLGEPQRSYPSIHITGTNGKTSTARMIEALLGAFEL
RTGRYTSPHVQSVTERISLDGAPISAERFIETYEDIKPYVEMVDARQEYRLSFFEVLTGM
AYAAFADAPVDVAVVEVGMGGTWDATNVIDGDVAVVTPIDLDHTDRLGETPGEIAKEKAG
IVKQDATVILAQQPVDAAQVLLKKAVEVDATVAREGLEFGVVARQVAVGGQLLTLRGLGG
EYEEVYLPLHGPYQAHNAAVALAAVEAFFGVGSQRPEPLDIDTVRKAFAAVSSPGRLEVV
RRSPTVVLDAAHNPAGARATAEAVGEAFDFSRLIGVVGASGDKNVRGLLEAFEPIFAEVV
ITQNSSHRAMDADELAAIAVEVFGEERVQVEPRLPDALEAAITLAEEEGEFAGGGVLVTG
SVITVGEARLLLGRG
NT seq
1488 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgacagcgacgaccccttcgacgagatcatctcggcagagaccgaccgcgacccc
gacctcgcggtcatcgaggccggcagccgcaccctgcgcacccagggcaccccgcccgag
gcacaggtgccgacccgccccgaggaccccgagctcgacaaggccctcagggacgtcgag
gcggagctcgccacgcgctggggcgagaccaagctggagccctccgtcagccgcatcgcc
gcgctgatggacgtcctgggcgagccgcagcggtcgtacccgtcgatccacatcacgggg
acgaacggcaagacctccacggcccgcatgatcgaggccctgctcggcgccttcgagctg
cgtacggggcggtacaccagccctcacgtgcagtccgtcaccgagcgcatcagcctcgac
ggggcgccgatctccgccgagcgcttcatcgagacgtacgaggacatcaagccgtacgtc
gagatggtggacgcgcggcaggagtaccggctgtcgttcttcgaggtgctgaccggcatg
gcgtacgccgccttcgcggacgcgcccgtggacgtggccgtcgtcgaggtcggcatgggc
ggcacctgggacgccaccaacgtcatcgacggtgacgtcgccgtcgtcacgcccatcgat
ctcgaccacaccgaccggctcggcgagacgcccggcgagatcgccaaggagaaggccggc
atcgtcaagcaggacgcgacggtcatcctggcccagcagccggtcgacgccgctcaggtg
ctgctcaagaaggcggtcgaggtcgacgccacggtcgctcgggaagggctcgagttcggg
gtcgtcgcgcggcaggtcgccgtcggcgggcagctgctgacgctgcgcgggctcggcggg
gagtacgaggaggtctacctcccgctgcacggcccctaccaggcgcacaacgccgccgtc
gcgctcgccgccgtcgaggcgttcttcggcgtcggctcgcagcggcccgagccgctcgac
atcgacaccgtccgcaaggccttcgctgccgtgtcctcgccgggcaggctggaggtcgta
cggcggtctcccaccgtcgtgctggacgccgcccacaacccggcgggtgcccgcgccacc
gccgaggcggtcggtgaggccttcgacttcagccggctgatcggtgtggtcggggcgagc
ggcgacaagaacgtacgggggctcctggaggccttcgagccgatcttcgcggaggtcgtg
atcacgcagaactccagccaccgcgccatggacgccgacgagctggccgcgatcgccgtc
gaggtgttcggcgaggagcgcgtccaggtcgagccgcggctgcccgacgccctggaggcc
gcgatcacgctggccgaggaggagggcgagttcgcgggcggcggtgtgctcgtcaccggt
tccgtcatcactgtcggcgaggcccgactgcttctggggaggggctga
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