Sorex araneus (European shrew): 101542134 Help Entry 101542134         CDS       T07854                                  Symbol ZAP70 Name (RefSeq) tyrosine-protein kinase ZAP-70   KO K07360   tyrosine-protein kinase ZAP-70 [EC:2.7.10.2] Organism sara  Sorex araneus (European shrew) Pathway sara04014   Ras signaling pathway sara04064   NF-kappa B signaling pathway sara04650   Natural killer cell mediated cytotoxicity sara04658   Th1 and Th2 cell differentiation sara04659   Th17 cell differentiation sara04660   T cell receptor signaling pathway sara05135   Yersinia infection sara05235   PD-L1 expression and PD-1 checkpoint pathway in cancer sara05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:sara00001]  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     101542134 (ZAP70)    04064 NF-kappa B signaling pathway     101542134 (ZAP70)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     101542134 (ZAP70)    04660 T cell receptor signaling pathway     101542134 (ZAP70)    04658 Th1 and Th2 cell differentiation     101542134 (ZAP70)    04659 Th17 cell differentiation     101542134 (ZAP70)  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     101542134 (ZAP70)   09171 Infectious disease: bacterial    05135 Yersinia infection     101542134 (ZAP70)   09163 Immune disease    05340 Primary immunodeficiency     101542134 (ZAP70)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:sara01001]     101542134 (ZAP70) Enzymes [BR:sara01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      101542134 (ZAP70) Protein kinases [BR:sara01001]  Non-receptor tyrosine kinases   SYK family    101542134 (ZAP70) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 ABC1 Haspin_kinase Motif Other DBs NCBI-GeneID:  101542134 NCBI-ProteinID:  XP_004609351 LinkDB All DBs Position Unknown AA seq 620 aa AA seqDB search MPDPAAHLPFFYGSISRAEAEDHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFP IERQLNGTYAIAGGKAHCGPAELCEFYSRDPDGLPCNLRKPCNRPPGLEPQPGVFDSLRE AMVRDYVRQTWKLEGDALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAERKLYSG SQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLVEYLK LKADGLIFCLREPCPNASASASTGAAAPTLPAHPSTFTHPQRRVDTLNSDGYTPEPARLA SPEKPRPMPMDTSVYESPYSDPEELKNKKLFLKRDNLIMADIELGSGNFGSVRQGVYRMR KKQIDVAIKVLKHGTEKANKDDMMREAQIMHQLDNPYIVRLIGLCQAEALMLVMEMASSG PLHKFLLGKKEEIPISNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDF GLSKALGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEAFSYGQKPY KKMKGPEVMAFIEQGNRMECPPGCPPEVYKLMNDCWIYKWEERPDFLTVEQRMRTHYYSL ASKAENPGGDEKGAGVAAAT NT seq 1863 nt NT seq  +upstreamnt  +downstreamnt atgccggaccccgcggcgcacctgcccttcttctacggcagcatctcacgcgccgaggcc gaggaccatctgaagctggcgggcatggccgacgggctcttcctgctgcgccagtgcctg cgctcgctcggcggctacgtgctctcgctggtgcacgacgtgcgcttccaccacttcccc atcgagcggcagctgaacggcacctacgccatcgccggcgggaaggcgcactgcggccct gccgagctctgcgagttctactcccgcgaccccgacgggctgccctgcaacctgcgcaag ccctgcaaccggccgccggggctcgagccgcagcccggcgtcttcgacagcctgcgcgaa gccatggtgcgcgactacgtgcgccagacgtggaagctggagggcgatgctctggagcag gccatcatcagccaggccccgcaggtggagaagctaatcgccaccaccgctcacgagcgc atgccctggtaccacagcagcctaacgcgggaggaggccgagcgcaaactttactctggc tcgcagaccgacggcaagttcctgctgagaccccggaaggaacagggcacttacgcgttg tccctaatctatggaaagactgtgtaccactacctcatcagccaggacaaggcaggcaaa tactgcatccctgagggcaccaagtttgacactctctggcagctggtggagtacctgaag ctgaaggctgatgggctcatcttctgcctgcgagagccgtgccccaatgccagcgctagc gccagcacaggggctgcagctcccactctcccagctcacccttccaccttcacccatcct cagaggcgggttgacacactcaactcagatggatacactcctgagccagcacgccttgca tccccggagaaaccgaggccaatgcccatggacacaagcgtgtatgagagcccctacagc gaccccgaggagctcaagaacaagaagctcttcctgaagcgtgacaacctcatcatggct gacatcgaacttggcagcggcaactttggctctgtgcgtcagggcgtctaccgcatgcgc aagaagcagatcgatgtggccatcaaggtgttgaaacatggcacagagaaggcgaataag gatgacatgatgcgtgaggcacagatcatgcaccagctggacaatccctacatcgtgcgg ctcatcggcctatgccaggctgaggcactcatgctggtcatggagatggcgagcagtggg cccctgcacaagttcctcctggggaagaaggaggagattccaatcagcaatgtggcagag ctgctgcaccaagtgtccatggggatgaagtacctggaggagaagaactttgtgcaccga gacctagcagcgcgcaacgtccttctagtgaaccggcactacgccaagatcagcgacttt gggctctctaaggccctgggtgccgacgacagttactacacagcccgctcagcgggcaag tggccgctcaagtggtatgcaccggagtgtatcaacttccgcaagttctccagccgtagt gacgtgtggagctatggagtcaccatgtgggaagccttttcctatggccagaaaccctac aagaagatgaaggggccggaggtcatggctttcattgagcagggcaataggatggagtgc ccaccgggctgcccaccggaagtgtacaaactcatgaatgactgctggatctacaagtgg gaggagcgcccagactttctgaccgtggagcagcgcatgcgcacccactactacagcctg gcgagcaaggccgagaaccctggtggagatgagaagggagccggggtggcagcagccacc tga

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