Sorex araneus (European shrew): 101542247
Help
Entry
101542247 CDS
T07854
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
sara
Sorex araneus (European shrew)
Pathway
sara00010
Glycolysis / Gluconeogenesis
sara00020
Citrate cycle (TCA cycle)
sara00620
Pyruvate metabolism
sara00785
Lipoic acid metabolism
sara01100
Metabolic pathways
sara01200
Carbon metabolism
sara01210
2-Oxocarboxylic acid metabolism
sara04066
HIF-1 signaling pathway
sara04922
Glucagon signaling pathway
sara05230
Central carbon metabolism in cancer
sara05415
Diabetic cardiomyopathy
Module
sara_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sara00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
101542247 (PDHA1)
00020 Citrate cycle (TCA cycle)
101542247 (PDHA1)
00620 Pyruvate metabolism
101542247 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
101542247 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
101542247 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
101542247 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
101542247 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101542247 (PDHA1)
Enzymes [BR:
sara01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
101542247 (PDHA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
101542247
NCBI-ProteinID:
XP_004612281
LinkDB
All DBs
Position
Unknown
AA seq
397 aa
AA seq
DB search
MRKMLAAVFRVLSGASPKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPETTVLTREE
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLYDGQLLLPLLQEACCVGLEAGINPTDH
LITAYRAHGFTLTRGLTVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPL
GAGIALACKYNGKDEICLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSV
ERAAASTDYYKRGDFIPGLRVDGMDVLCVREATKFAAAHCRSGKGPILMELQTYRYHGHS
MSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNNNLASVEELKEIDVEVRKEIEDAAQFA
TADPEPPLEELGYHIYSSEPPFEVRGANQWIKYKSIS
NT seq
1194 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgctgtcttccgcgtgttgtcaggcgcctccccgaagcccgca
agcagagtgctggtggcatcccgtaattttgcaaatgatgctacgtttgaaattaagaaa
tgcgatcttcaccgtctggaggaaggtcctcctgaaacaacagtgctcaccagggaggaa
gggctcaagtactacaggatgatgcagactgtgcgcagaatggagttaaaggcagatcag
ctgtacaagcagaagattattcgtggcttctgtcacttgtatgatgggcagctgcttctt
cctctcttgcaggaagcttgttgtgtgggcttggaggctggcataaaccctacagaccat
cttatcacggcctatcgggctcacggctttaccttaactcgtggtcttactgtcagggag
attcttgccgagcttacaggtcgaagaggaggctgtgctaaaggaaaagggggctccatg
cacatgtacgctaagaacttctacgggggcaatggcatcgttggagcccaggtgcccttg
ggagctgggattgcactggcctgtaagtataatggaaaagatgagatctgtttgacttta
tatggcgatggtgctgctaatcagggtcagatttttgaagcttacaatatggcagccttg
tggaaattgccttgtattttcatctgtgaaaataaccgctatggtatgggaacatctgtc
gagagagcagcggccagcaccgattactacaagagaggcgacttcatcccaggactgagg
gtagatggaatggatgtcttatgtgtccgggaggcgacaaagtttgcagctgctcattgt
agatctggaaaggggcccatacttatggagctacagacttaccgttaccatggacacagc
atgagtgatcctggagtcagttatcggacacgagaagaaatccaggaagtaagaagcaag
agtgatcctatcatgcttctcaaggacagaatggtgaacaacaatcttgccagtgttgaa
gagttaaaggaaattgatgttgaagtgaggaaagaaattgaggatgctgcccagtttgcc
actgctgatccagaacctcctctggaagagctgggctatcacatctatagcagcgagcca
ccttttgaagttcgtggtgcaaatcagtggatcaagtataagtctattagttaa
DBGET
integrated database retrieval system
