Sorex araneus (European shrew): 101542669
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Entry
101542669 CDS
T07854
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
sara
Sorex araneus (European shrew)
Pathway
sara00562
Inositol phosphate metabolism
sara01100
Metabolic pathways
sara04014
Ras signaling pathway
sara04015
Rap1 signaling pathway
sara04020
Calcium signaling pathway
sara04024
cAMP signaling pathway
sara04070
Phosphatidylinositol signaling system
sara04919
Thyroid hormone signaling pathway
sara04933
AGE-RAGE signaling pathway in diabetic complications
sara05205
Proteoglycans in cancer
Module
sara_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
sara00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
101542669 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
101542669 (PLCE1)
04015 Rap1 signaling pathway
101542669 (PLCE1)
04020 Calcium signaling pathway
101542669 (PLCE1)
04070 Phosphatidylinositol signaling system
101542669 (PLCE1)
04024 cAMP signaling pathway
101542669 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
101542669 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
101542669 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
101542669 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
sara04131
]
101542669 (PLCE1)
Enzymes [BR:
sara01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
101542669 (PLCE1)
Membrane trafficking [BR:
sara04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
101542669 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
101542669 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
101542669
NCBI-ProteinID:
XP_004607409
LinkDB
All DBs
Position
Unknown
AA seq
2302 aa
AA seq
DB search
MTSEEITASVLIPVSQRKVLSSQSAVDENSEKDSDIRIPKHHIVSQSRPNSHTILQLNKL
KKESSGSNLPQILSLAGEKIISDENSNENCWDQSMPDSVKNLNINCNNILKNHQCGLPQS
QFYERCEPIPEEGLCLETGIPSSLERKVFPGIPLEIDGPPLGISSLGNQSSIIKSSRTNP
GSDRAVFHFHYEVDRRMSESFCALSDNLILDDCGNCVPLPGVTAEQNNKHVAYTCELMEL
EDNCDNKNGQLHCDHCDTSTDKRLCCEGSCGKANIICSNDNFCRQNFPDVPPAKTFINHL
EELSDNCEDTEEDFFRSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGRIGLEA
WSYIDQKRKGLLLPGEGIMELLSAVLIRQDGSQSPSEARWYPIYNAVRRGEETEDTIGSL
LHFFTKLPVSVTACERISVGPCLKQCIRDTVCEYRATLQRTSISQYITGSLLEATTSLGA
RSGLLSTLGGSTSRKMLKEHQPVPSMANSSALPSSSAGISKELIDLQPLIQFPEEVASIL
MEQEQNIYRRVLPVDYLCFLTRDLRSPECQRSLPCLKASISASILTSQDGEHNALEDLVM
RFNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKM
WQFMDQSDLETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDG
ASGLMKLCPRYNSQEEALEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSR
SLESEEEDSPGEGSNSRKNSLKEKARWQFIIGDLLDPENDIFDQHKEWDPHGSEEPQKAF
DHGTELIPWYVLSIRADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWIKPTTA
SPSSAKPKLGALSNTSEPGKFPLLGNAGLSSLAEGVLDLFSVKAVYMGHPSIDIHTVCVQ
NKLGSMVLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQR
QQWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSAEKPNMQRNNTL
GISTTKKKKKMLMRGESGEATDDETATRKVKMQKECRSRSGSDPQDNNEQEESEANAITA
PPNPLPSRRAHSLTTAGSPNVATGTSSPIRPVSFPVLSSSNKSPSSAWSSSSWHGRIKGG
MKGFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDLYAVPCNRASPESTPLYTNLT
IDENTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSL
GIFGVGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSVSMCHQGLLSFEGFARFLMDKDN
FASKNDESQENMKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELD
CWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAE
IFKTVFGEKLVTKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQL
ASMQAQVNNGGSANPPPANNEEEEEEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEY
NEEIPKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPG
LSTLNASGSSRGKERKSRKSIFGNNPGRMSPGEIASFNKTSGKSSYEGMRQAWEESTSPL
NPTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNP
NPLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPL
ERDLDSMEPAIYSLTIVSGQNVCPSNSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPM
WNEQFLFRVHFEDLLFLRFAVVENNSSAVTAQRIIPVKALKRGYRHLQLRNLHNEVLEIS
SLFINSRRMEENASGSTVPASLMFNTEERKCLQAHRVTVHGVPGPEPFTVFCINGSTKAK
QLLQQILTTEHDSRSIVTDYFLMEEKYFISKEKNECRKQPFQRVIGPEEEIMQILSSWFP
EEGYVGRIVLTQQENLDERSITQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVST
AQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDATSKKTSAPKSSQRVLLDQECVFQ
AQSKWKGAGKFILKLKEQVQASREDKRKGISFASELKKLTKSTKQPRGLPPPLQASASES
GQNKEEKPAGSLSPTDLIDSRQ
NT seq
6909 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaagaaattacagcttctgttcttatacctgtgtctcagagaaaagtgtta
tcttctcagtctgctgtagatgaaaatagtgaaaaggattcagacattaggattccaaag
catcacattgtcagtcagagcaggccaaattctcataccatcttacagctaaacaagctt
aaaaaggaatcttctggaagcaacttgccccaaattctctcactggcaggagagaaaata
ataagtgatgagaacagtaatgaaaactgctgggatcaaagcatgccagattctgtgaaa
aatcttaatattaactgcaataatatattgaaaaaccatcagtgtggccttcctcagagc
cagttttatgaaaggtgtgagcctatcccagaggagggcctgtgtttagaaactggaatt
ccttcttcactggaaagaaaggtgttccctggaatcccactggaaattgatggacctcca
ctgggcattagttccttaggaaatcagtcatcgatcataaagtccagtaggacaaaccct
ggcagtgacagggcggtatttcactttcattatgaagtggacagaagaatgtcagagtct
ttctgtgcactttcagataacctgattttggatgattgtggaaactgtgtcccactgcct
ggtgttacagcggagcaaaataataagcacgtggcatatacttgtgaactgatggaactg
gaagataactgtgacaataagaatgggcagctgcattgtgatcattgtgacacttcgact
gataaacgtttgtgctgtgaaggctcctgtggtaaggccaacataatatgttcaaatgac
aacttttgcagacagaacttccctgatgttccacctgccaagacctttataaaccatctt
gaggagctctctgataattgtgaagatacagaagaagacttttttagaagcaaaaaggag
cggtccaccttgttagtgaggagattttgtaaaaatgacagggaagttaagaaatctgtg
tatactggcaccagggcaattgtaaggacactaccttctggtcgcattggactggaagct
tggagttacattgatcagaaaagaaaaggcctcttattgcctggtgagggaataatggaa
cttctgtcagcagtgctgattaggcaagatggaagccaaagtccatcagaagcccggtgg
tatccgatctacaatgcagtaagaagaggagaagaaacagaagatacaattggatctctt
ctccatttcttcacaaagctcccagtctccgtgacagcttgtgaaaggattagtgttggt
ccatgcttaaagcaatgtatccgggacactgtatgtgagtatcgtgctactctccaaagg
acttccatctctcagtacatcaccggctctctcctagaagcgaccacatctttaggagca
agaagtggccttctcagtactttgggaggttccaccagtcgaaagatgctgaaagagcac
cagcccgtcccctctatggctaactctagtgccctcccctcaagttcagctgggatcagc
aaggaactgatagatctacagcccctcatccagttcccagaggaagttgccagcatcctg
atggagcaagaacagaatatttaccgaagagtcttacctgttgactacctttgctttctg
acccgggacttgagatctccagaatgccagaggtccctgccctgcctcaaagcgtccatc
tcagcgtctattcttacctcccaggatggtgaacacaacgcccttgaggatcttgtcatg
cggtttaatgaggtgagttcctgggttacatggctgatcctcactgcgggctccatggag
gaaaagagggaagttttctcatatctggtgcatgtggccaaatgctgctggaatatggga
aactataatgctgtcatggagttcttggctggcctcaggtctcgaaaagttttaaaaatg
tggcagtttatggaccagtccgacctggagaccatgaggagtctgaaggacgccatggcc
cagcatgaatcctcctgcgagtacaggaaggtggtgacccgggcgctgcacatccccggg
tgtaaggtggttccattctgtggtgtgtttctgaaggagctctgtgaggtacttgacgga
gcctctggcctcatgaagctttgcccacggtacaattcccaagaggaagcactagagttt
gtcgccgattatagtggacaagataatttcttacaacgagtgggacaaaatggcttgaag
aattcagagaaggagtcgaccgtcaacagcatcttccagatcatccggagctgcagtcgg
agtctggagtcagaggaagaagacagccccggggagggcagcaactctagaaagaattcc
ttaaaggaaaaagcgcgctggcaatttatcattggagatttgttggatcctgaaaatgac
atctttgatcagcacaaagaatgggatcctcatgggtcagaagagccacagaaagccttt
gaccatgggacagagctcatcccatggtatgtgctgtccatccgtgctgatgtgcaccag
ttcctgctacagggggccacggtcattcactatgaccaggacacacacctctctgcccgc
tgcttcctccagcttcagcctgacaacagcacactaacctggataaagcctaccactgcc
tccccgtccagtgctaaacctaaacttggtgccctcagtaatacatctgagcctggcaaa
ttccctttactgggcaatgctggattaagcagcctcgcagaaggggtcttggacctgttt
tcggtgaaggctgtgtacatgggacaccctagcattgatatacacactgtgtgtgttcag
aacaaactgggaagcatggttctctcagagactggcgtcacactgctctatgggcttcag
accacagacaacagattactgcacttcgtggcaccaaagcacacagctaaaatgctcttc
agtggattgttggaacttactagagctgtgagaaagatgcggaagttccccgaccaacga
cagcagtggctgaggaaacagtatgtcagcctctatcaggaagatggacggtatgaaggt
ccaactctggctcatgctgtggagttatttggtggcagacgatggagtactcgaaacccc
agccctgggacatcagcaaagagtgctgagaagccaaacatgcagagaaacaacaccttg
ggcataagcaccaccaagaaaaaaaagaaaatgcttatgaggggtgagagtggagaggca
actgatgatgagacagccaccagaaaggtcaaaatgcaaaaagagtgtcggagccgcagt
ggttctgacccacaagacaataatgaacaagaggaatcagaggcaaatgccatcactgcc
cctcccaaccctctcccttccagacgagcacactctctgacgacggctggctcccctaac
gtggctactgggacatcatctcccatcaggccagtgtccttccctgtgctgtcttcttca
aacaagagtccatccagtgcttggagcagtagcagctggcatgggcggatcaaaggagga
atgaagggctttcagagcttcatggtttcagacagcaacatgagttttgttgaatttgtt
gagctgttcaaatcattcagtgtaagaagccgcaaggacctgaaggatctcttcgacctc
tatgccgtgccctgcaacagagccagccctgagtcaaccccgctctacacaaacctaaca
attgatgaaaataccagtgatctccaacccgacctcgatttgttgaccagaaatgtctca
gatttgggattgttcatcaagagtaaacagcagctgtcagacaaccagagacagatatcc
gatgccattgctgctgcaagtattgtgacaaatggcactgggattgagagcacatcttta
ggcatctttggagttggcatactccagcttaatgactttcttgtgaattgccaaggggaa
cattgcacctatgacgagatcctcagcatcatccagaagtttgagccaagtgttagcatg
tgtcatcagggcctactgtcatttgaaggatttgccaggtttctgatggataaagataat
tttgcctcaaagaatgatgagtcgcaggagaacatgaaagaattacagctgcccctctcc
tactattacattgaatcttcacacaatacctacctcacaggccaccagctgaaaggagaa
tcctcagtagaactctacagccaggtcctcctgcaaggctgtaggagcgtagagttggac
tgctgggatggggatgatgggatgcctattatttatcatggacacacactgacaacaaaa
attcccttcaaggaagtggttgaagccattgatcgaagtgccttcatcaactctgacctg
ccgatcatcatatcaattgagaaccactgctcattgcctcagcaacgaaaaatggcagaa
atttttaagactgtgtttggagagaaactggtgactaaattcttgtttgagagtgatttc
tcagatgatcccatgcttccttcacctgaccaacttcggaggaaagtgcttcttaaaaat
aagaaactaaaagcccatcagacacctgtggatatcttaaagcagaaggctcatcagtta
gcttctatgcaagctcaggttaataatggcgggagtgccaaccccccacctgctaataat
gaagaagaggaagaggaagaagacgaatatgattatgactatgaatctctctctgacgac
aatattctagaagatagacctgaaaataaatcatgtaatgacaagctccagtttgaatat
aatgaagaaatacccaagaggataaagaaagcagataattctgcttgcaacaaaggcaag
gtatatgacatggaactgggagaagagttttatcttccacaaaataaaaaggaaagcaga
cagattgcaccagagctttctgatcttgtcatctactgccaagcagtaaaatttccaggc
ctgtcaactctaaatgcatctggctctagcagaggaaaagaaaggaaaagcaggaagtcc
atttttggcaacaatccgggcagaatgagccctggggagatagcatcatttaacaaaaca
tctggaaaaagttcctatgaaggaatgcgacaggcctgggaggaatccacttcccccctc
aacccaaccacgtccctcagcgctatcattagaactcccaaatgttaccatatctcatca
ctgaatgaaaatgccgccaaacgtctgtgtcgcaggtattctcagaaactgatccagcac
accgcctgccagctgctgaggacatacccggctgccacccgcatcgactcgtccaacccc
aaccccctcatgttctggctccatgggatacagctcgtggcactcaactaccagacagat
gacctccctttgcatttgaatgctgccatgtttgaggccaatggtggctgtggttatgtt
ttgaaacccccagttctgtgggacaaaaactgtcccatgtaccagaagttttctcccctg
gaaagagacctggacagcatggagcctgccatctattctttaactattgtttctggtcag
aacgtgtgtccaagtaacagcacgggaagcccctgcatcgaagttgatgtcctgggcatg
cctctagacagctgccatttccgcaccaagcccatccatcgaaacactctgaaccccatg
tggaatgaacagtttctcttccgggttcactttgaagatctgctgtttcttcgttttgca
gttgtggaaaacaacagctcagcagtcacagctcagagaatcatccctgtcaaggcttta
aaaagaggatatcggcatcttcaacttcgaaacctccacaatgaagtcttggagatctct
agcttgttcatcaatagcagaaggatggaagaaaatgcctctggcagtactgtgccagcc
tctttgatgtttaacacagaagaaagaaagtgtttgcaggctcatagagtcacagtgcat
ggggtcccgggtccagagcctttcactgtgttctgtataaatggaagcaccaaggcaaag
cagctgctccagcagattctaaccactgaacatgacagtagatctattgtcacagactat
tttttgatggaagaaaaatactttatatctaaagagaagaatgaatgtaggaaacaacca
ttccagagagtcatcggtccagaagaagagatcatgcagattttaagcagctggtttccg
gaagagggatatgttggcagaattgtcttaacccagcaagaaaatttagatgaaaggagc
atcacccaagatgacaaggaggtgatcttgagctcggaggaagagagcttcttcgtccaa
gtgcatgatgtttctccagagcaacctcgaacagtcatcaaagcccctcgtgtcagtacc
gcacaggatgtcattcagcagactttatgcaaagctaaatattcttatagcatcctgagc
aatcccaacccaagtgattatgtacttttggaagaggtggtaaaggatgctaccagcaag
aagacttctgcccccaagtcctcccagagggtccttttggatcaggaatgtgtgttccaa
gcccaaagcaagtggaaaggtgcagggaaattcatccttaaactaaaagaacaagtacag
gcatcccgagaggacaaaagaaaaggcatttcttttgcaagtgaactcaagaagctcacc
aagtcgaccaaacagccccgtggactgccaccccctttgcaggcatcagcctcagaaagt
ggccaaaataaggaggagaaaccggcgggcagcttgtctcccactgacctgatagactct
cggcagtga
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integrated database retrieval system
