Sorex araneus (European shrew): 101547499
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Entry
101547499 CDS
T07854
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
sara
Sorex araneus (European shrew)
Pathway
sara01524
Platinum drug resistance
sara04010
MAPK signaling pathway
sara04071
Sphingolipid signaling pathway
sara04141
Protein processing in endoplasmic reticulum
sara04210
Apoptosis
sara04530
Tight junction
sara04668
TNF signaling pathway
sara04714
Thermogenesis
sara04722
Neurotrophin signaling pathway
sara04932
Non-alcoholic fatty liver disease
sara04936
Alcoholic liver disease
sara05010
Alzheimer disease
sara05012
Parkinson disease
sara05014
Amyotrophic lateral sclerosis
sara05016
Huntington disease
sara05017
Spinocerebellar ataxia
sara05022
Pathways of neurodegeneration - multiple diseases
sara05208
Chemical carcinogenesis - reactive oxygen species
sara05417
Lipid and atherosclerosis
sara05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
sara00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
101547499 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101547499 (MAP3K5)
04668 TNF signaling pathway
101547499 (MAP3K5)
04071 Sphingolipid signaling pathway
101547499 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
101547499 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
101547499 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
101547499 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
101547499 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
101547499 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
101547499 (MAP3K5)
05012 Parkinson disease
101547499 (MAP3K5)
05014 Amyotrophic lateral sclerosis
101547499 (MAP3K5)
05016 Huntington disease
101547499 (MAP3K5)
05017 Spinocerebellar ataxia
101547499 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
101547499 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101547499 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
101547499 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101547499 (MAP3K5)
04932 Non-alcoholic fatty liver disease
101547499 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
101547499 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
sara01001
]
101547499 (MAP3K5)
Enzymes [BR:
sara01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
101547499 (MAP3K5)
Protein kinases [BR:
sara01001
]
Serine/threonine kinases: STE group
STE11 family
101547499 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
101547499
NCBI-ProteinID:
XP_012788319
LinkDB
All DBs
Position
Unknown
AA seq
1108 aa
AA seq
DB search
MSDAFRQPSLFYHLGVRESFSMANNIILYCDTNTDSLQSLKEIICQKNTMCTGNYTFVPY
MVTPHSKVYCCDSSFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKMAQASSSQYFQES
ILSDIRKARNLYTGKELAAELARIRQRVDNIEVLTSDIVINLLLSYRDIQDYDSIVKLVE
TLEKLPTFDLASHHHVKFHYAFALNRRNLPGDRAKALDIMIPLVESEGQVASDMYCLVGR
IYKDKFLDSNFMDTESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSFELRKV
GVKISSLLGKKGNLENLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWYLKSIV
ETILIYKHFVKLTTEQPVAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYL
SINNEVEEKTISIWHVLPDDKKGIHEWNFSAASVRGVSISKFEERCCFLYVLHNSDDFQI
YFCTELHCKKFFDMVNTITEEKGRSTEEGDCEADSLEYDYEYDENGDRVVLGKGTYGIVY
AGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFME
QVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYS
GVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKPADIWSLGCTIIEMA
TGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLID
EFLKVSSKKKKAQPKLSVLSAGSNAEYLRSISLPVPVLVEDTSSSSEYGSVSPDTELKVD
PFSFKARAKSCGEKDVKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLKKDSERRATL
HRILTEDQDKVVRNLMESLAQGAEEPKLKWEHITTLIASLREFVRSTDRKIIATTLSKLK
LELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAITILVPEL
RPHFSLASESDTADQEDLDVEDDHEEQPSNQNARRPPAAAAAAAPAVVEDPVATSGVSTL
SSTVSHDSQSAHRSLTMQLGRMKIETNR
NT seq
3327 nt
NT seq
+upstream
nt +downstream
nt
atgagtgatgcgttccggcaaccatccttgttttaccaccttggagtgagagaaagtttc
agcatggccaacaacatcatcctctactgtgataccaatacagactctttgcagtccctg
aaggaaatcatttgtcagaagaacactatgtgcactgggaactacacatttgttccttac
atggtgacaccacacagcaaggtgtactgctgtgacagcagcttcatgaagggcttgaca
gagctcatgcagcccaactttgaactgcttctgggacctatatgcttacctctggtggat
cgtttcattcagcttttgaagatggcacaagcaagttccagccagtatttccaagaatcc
atactcagtgatatcaggaaagctcgtaacttatacactggtaaagaattggcagctgaa
ctggcaagaattcggcagcgagtagacaatattgaagtcttaacatcagatattgtcata
aatcttttactttcctacagagatatacaggactatgattctattgtgaagctggtagag
actttggaaaagctaccaacctttgatttggcctcccatcaccatgtgaaatttcattat
gcatttgcactgaataggagaaatctccctggagatagagcaaaagctcttgatataatg
attcccctggtggaaagtgaagggcaagttgcttcagatatgtattgcttagttggtcga
atctacaaagataaatttttggactctaacttcatggacactgaaagtagagaccatgga
gcttcatggttcaaaaaggcatttgaatctgagccaaccctgcagtcaggaataaattat
gcggttctcctcctagcagctgggcaccagtttgaatcttcctttgagctccggaaagtc
ggagtgaagataagcagtcttcttggaaaaaagggaaatttggaaaacctccagagctac
tgggaagttggattttttctgggggctagtgtcttggccaatgaccacatgagagtcatt
caggcatctgagaagctcttcaaactaaagacacctgcatggtatctcaaatctattgta
gagaccattttgatatataaacattttgtgaaattgactacagaacaacctgtggcaaag
caggaacttgtggacttctggatggatttcctggtcgaagccacaaagacagatgtgact
gtagttaggtttccagtattaatattagaaccaacaaaaatctatcagccttcatactta
tcaatcaacaatgaagttgaggaaaagacaatatctatttggcatgtgctcccagatgac
aagaaaggtatacatgagtggaattttagtgctgcttctgtcaggggagtgagtatttct
aagtttgaagagcgatgctgctttctttatgtgcttcacaattctgatgacttccagatc
tatttctgtacagaacttcattgtaaaaagttttttgatatggtgaacaccataactgaa
gaaaagggaagaagcacagaagaaggggattgtgaggctgactccctggagtatgactat
gaatatgatgaaaatggtgacagagttgttttaggaaaaggcacatatggaattgtctat
gctggtcgggacctgagcaatcaagtcagaattgctattaaagagattccagagagagat
agcagatattcccagcctctacatgaagaaatagcattgcataagcatctgaagcacaaa
aatattgtccagtatctgggctctttcagtgaaaatggtttcattaaaatcttcatggaa
caggttccaggaggaagtctttctgctcttcttcgttccaaatggggcccactaaaagac
aatgagcaaaccattggcttttatacaaaacaaatactagaaggattaaaataccttcat
gacaatcagatagttcaccgggatataaagggtgacaatgtattgattaacacttacagt
ggtgttctcaagatctcagacttcgggacatcaaagaggcttgctggcataaatccgtgt
actgaaacttttacaggtactcttcaatatatggcaccagaaataatagataaaggacca
agaggctacgggaaaccagcggacatttggtctttgggctgcacgatcattgaaatggcc
acagggaaaccgcccttttacgaactgggagaaccacaagcagctatgttcaaggtgggg
atgtttaaagtccacccagagatcccagagtccatgtcagcagaagccaaggcattcata
ttgaaatgttttgaaccagaccctgacaagagagcctgtgctaatgacttacttattgat
gaattcttaaaagtctcaagcaaaaagaaaaaggcacaacctaagctttcagttctttca
gctggatcaaatgcagagtatctgaggagcatttccttgccagtacctgtcctggtggag
gacacaagcagcagcagtgagtatggctctgtttctcccgacacggagctcaaggtggac
cccttctccttcaaagcaagagccaagtcctgcggagaaaaggacgtcaaaggaatacgg
acactctttttaggcattccagatgagaattttgaagatcacagtgctccaccttctcct
gaagaaaaagattctggattctttatgctgaagaaggacagtgaacgacgggccaccctc
cataggatcctgacagaagaccaagacaaagtcgtgagaaacttaatggaatctttggct
cagggggccgaagagcctaaactaaaatgggagcacatcacaaccctcattgcaagcctc
agagaatttgtgaggtccactgacagaaaaatcatagctaccacgctctcaaaactgaag
ttagagcttgatttcgacagccacggcattagtcaggtccaggtggtgctcttcggtttt
caagacgccgtcaataaagttcttcggaatcataacatcaagccacactggatgtttgct
ttagacagtatcatcagaaaagcggtgcagacagctatcaccattctggtgccagaattg
aggccacattttagcctagcctctgagagcgacactgctgatcaagaagacttggacgta
gaagatgaccatgaggaacagccatcaaaccagaatgcacgaagacctcctgctgcggct
gcagctgctgccccggctgtggtggaggatcctgtggctacttcaggggtgagcacgctc
agttccacagtgtctcatgattcccagagtgctcaccggtcacttactatgcagctgggg
aggatgaagattgaaaccaataggtga
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