Sorex araneus (European shrew): 101550416
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Entry
101550416 CDS
T07854
Symbol
ACACA
Name
(RefSeq) acetyl-CoA carboxylase 1 isoform X1
KO
K11262
acetyl-CoA carboxylase / biotin carboxylase 1 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
sara
Sorex araneus (European shrew)
Pathway
sara00061
Fatty acid biosynthesis
sara00620
Pyruvate metabolism
sara00640
Propanoate metabolism
sara01100
Metabolic pathways
sara01212
Fatty acid metabolism
sara04152
AMPK signaling pathway
sara04910
Insulin signaling pathway
sara04922
Glucagon signaling pathway
sara04936
Alcoholic liver disease
Module
sara_M00082
Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:
sara00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
101550416 (ACACA)
00640 Propanoate metabolism
101550416 (ACACA)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
101550416 (ACACA)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
101550416 (ACACA)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
101550416 (ACACA)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
101550416 (ACACA)
04922 Glucagon signaling pathway
101550416 (ACACA)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101550416 (ACACA)
Enzymes [BR:
sara01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
101550416 (ACACA)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
101550416 (ACACA)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
101550416 (ACACA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
MetallophosN
Motif
Other DBs
NCBI-GeneID:
101550416
NCBI-ProteinID:
XP_004608652
LinkDB
All DBs
Position
Unknown
AA seq
2383 aa
AA seq
DB search
MWWSTLMSILRASSFWRWISAQTIRILRAVRAHCERIMDEPSSLAKSLELNQHSRFIIGS
VSEDNSEDEISSLVKLDLLEEKEGSLSPASVGSDTLSDLGISSLQDGLALHMRSSMSGLH
LVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYE
MFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQ
AVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGS
GLRVDWQENDFSKRILNVPQELYEKGYVKDVDDGLKAAEEVGYPVMIKASEGGGGKGIRK
VNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRR
HQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQ
VEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGVSPWGDAPIDFENSAHVPCPRG
HVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSW
GENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQLNRIDTGWLDRLIAEKVQA
ERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQVLPAHTLLNTVDVELIYEGVKYVL
KVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTC
VFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAAESGCVHYVK
RPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPRIQSTALRGEKLHRVFHYVLDNLVNV
MNGYCLPDPFFSNRVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNVEKSIKKEMA
QYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHM
KAVVMDLLRQYLRVETQFQSGHYDKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTM
LIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESI
FLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYEL
NSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRMSFSSNLNHYGMTHVASVSDVLLD
NSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSPPQSPTFPEAGHTSLYDEDKVPRD
EPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLVEHGIRRLTFLVAQKDFRKQVNYE
VDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHL
YLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNN
TNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTPTG
KAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLL
QSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSAQAFLPSPPLPSDMLTYTELVLDDQG
QLVHMNRLPGGNEIGMVAWKMTLKSPEYPEGRDIIVIGNDITYRIGSFGPQEDLLFLRAS
ELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVDPEDPYKGYKYLYLTPQDYKRVSA
LNSVYCEHVEDEGESRYKITDIIGKEEGLGAENLRGSGMIAGESSLAYDEIITISLVTCR
AIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHS
TVCDDFEGVFTILHWLSYMPKSVHSSVPLLNSKDPIDRIIEFVPTKAPYDPRWMLAGRPH
PTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPAN
LDSEAKIIQQAGQVWFPDSAFKTFQAIKDFNREGLPLMVFANWRGFSGGMKDMYDQVLKF
GAYIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTINPRHMEMYADRESRGSVLEPEGT
VEIKFRKKDLVKTMRRVDPVYIHLAERLGTPELSAAERKELENKLKEREEFLIPIYHQVA
VQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLRRLLLEDLVKKKIHNANPELTDGQ
IQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTEEDGVRSVIEENIKYISRDYVLKQ
IRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILSTMDSPST
NT seq
7152 nt
NT seq
+upstream
nt +downstream
nt
atgtggtggtccactctgatgtcaatcttgagggctagttctttttggaggtggatatct
gctcagacaataagaattttaagagctgtgagagctcattgtgagagaataatggatgaa
ccttcctccttggccaaatctctggagctgaaccagcattcccgatttataattggctcc
gtatctgaggataactcagaggatgagatcagcagcttggtgaagctggacctgctagag
gagaaggagggctctctgtcaccagcatccgttggctcagatactctttctgacttaggg
atctctagcctacaggatggtttggccttacacatgagatccagcatgtctggcttgcat
ctagtaaagcaaggtcgagaccgaaagaaaatagactcacaaagagatttcactgtagct
tctccagcagaatttgttacccgttttggaggaaataaagtgattgagaaggttcttatt
gccaacaatggcatagcagcagtgaaatgcatgcggtctatccgtcgatggtcttatgaa
atgtttagaaatgaacgtgcaatccgatttgttgtcatggtgacacctgaagaccttaaa
gccaatgcagaatatatcaagatggcagatcactatgtaccggtgcctggaggacccaac
aacaataactatgcaaatgtggaattgatccttgatattgctaaaagaattccagtacaa
gcagtgtgggctggctggggtcatgcttctgaaaatcccaagcttccagaactacttttg
aagaatggtatcgccttcatgggtcctcctagccaggccatgtgggctttgggggataaa
atcgcatcttccatagtggctcagactgcaggtatcccaactcttccctggagtggcagt
ggtcttcgtgtggactggcaagaaaatgatttttcaaaacgtatcttaaatgttccccag
gaactttatgaaaaaggttatgtaaaggatgtggatgatggactgaaggcagcagaagaa
gtgggatatccagtaatgatcaaggcctcagaaggaggaggaggaaagggaattcggaaa
gtcaataatgcagacgacttccctaatctcttcagacaggttcaagctgaagtccctgga
tcacctatatttgtaatgagattggccaaacagtcacgtcatctggaggtgcagatctta
gcagatcagtatggcaatgccatctctttgtttggtcgtgattgctcagtacagcggagg
catcagaagattattgaagaggcacctgctgctattgctactccagcagtattcgaacac
atggaacagtgtgcggtgaaacttgccaaaatggttggttatgtgagtgctggaactgtg
gaatacctctacagccaagatggcagcttctacttcctggaactgaatccccggctacag
gtggagcacccttgtacagaaatggtagctgatgtcaatctccctgcagcacagctccag
attgccatggggatccctctgtacagaatcaaggatattcgtatgatgtacggtgtatct
ccctggggtgatgcacccattgattttgaaaattctgctcatgttccttgcccacggggc
cacgttattgctgctcggatcactagtgaaaatccagatgagggttttaagccaagctca
ggaacagttcaggagctgaatttccgcagcaacaagaatgtttggggttattttagtgtt
gctgctgcagggggacttcatgaatttgctgattcccaatttggtcactgcttttcctgg
ggagaaaacagagaggaagcaatttcaaacatggtggtggcgttgaaggaactgtctatt
cggggtgattttcgaacgacagttgaatacctgatcaaattgttagagacggaaagcttt
cagttgaatagaattgacactggatggctggacagactgatagcagaaaaagtacaggca
gagcgacctgacaccatgttgggagtcgtatgtggggctctccacgtggccgacgtgagc
ctgcggaatagcatctctaacttccttcattccttagaaaggggtcaagtccttcctgct
cacacacttctgaatacagtggatgttgaacttatctatgagggagtcaaatatgtcctt
aaggtgacccgtcaatcccccaactcctatgtggtgatcatgaatggctcctgcgtggag
gttgatgttcatcggctgagtgacggtggactgcttttgtcctacgacggcagcagctat
accacatatatgaaggaggaggtggaccgatatcgaattacaattggcaataaaacctgt
gtgtttgagaaggaaaatgacccttcagtgatgcgctcaccttctgctgggaagttaatc
cagtacattgtggaagatgggggccatgtgtttgctggccagtgctatgcagagattgag
gtaatgaagatggtaatgaccttaacagctgcagagtctggctgtgttcattatgtcaag
cggcctggagcagctcttgatccaggatgtgtaatagccaagatgcagttggacaacccc
agcaaggtccagcaggctgagcttcacacaggtagtctgccacggattcagagcaccgct
ctcagaggcgagaagctccatcgagtgttccactatgtcctggataacctggtcaatgtg
atgaatgggtactgccttccagatcctttcttcagcaacagggtaaaagactgggtggag
cggttgatgaagaccctcagagatccctcattgcctctcctagagttgcaagatatcatg
accagtgtctctggccgtattcctcctaacgtggagaagtctatcaagaaagaaatggct
cagtatgctagcaacatcacatcagtcctttgtcagtttcctagccaacagattgccaat
attctagatagccatgcagctacattgaaccggaaatctgaacgggaagtcttcttcatg
aatacccagagcatcgtccaactggtacagaggtaccgaagtggcatccgaggccacatg
aaggctgtagtgatggacctgctgcggcagtacctgagagtagagacacagtttcagagt
ggtcactatgacaaatgtgtgtttgcccttcgggaggagaacaagagtgacatgaacact
gtactgaactatatcttctctcatgctcaagtcaccaagaagaatcttctggtcacgatg
cttattgatcagttgtgtggccgggatcctactcttactgatgagctgctgaatatcctc
accgagctaactcaactcagtaagacgacaaatgctaaagtggcacttagagcacgccag
gttcttattgcttcccatttgccatcatatgagcttcgtcataaccaagtagagtccatc
tttctgtcagctattgacatgtacggacatcaattttgcatcgaaaacctgcagaaactc
atcttatcagaaacatctatttttgatgttctaccaaacttcttctatcatagcaaccag
gtcgtgaggatggcagctctggaggtctatgttcgaagggcttatattgcctatgaactt
aacagtgtacagcaccgccaacttaaggacaacacgtgtgtggtggaattccagttcatg
ctccccacttctcatcccaacagagggaacatccccacgctaaacagaatgtccttctcc
tccaacctcaaccactacggcatgactcacgtcgctagtgtcagtgacgtgctgttggac
aattcgttcactcccccatgccagcggatgggtggaatggtctctttccggactttcgaa
gattttgtcaggatctttgatgaagtgatgggctgtttctgtgactctccaccccaaagc
cccacattccccgaggcaggtcacacatctctgtatgatgaagacaaggtccccagggat
gaaccaattcatatcctgaatgtggctatcaagactgactgtgatattgaggacgacaga
ctggcagctatgttcagagagtttacccagcaaaataaagctaccctggttgaacatgga
atacggcgccttactttcttggttgcacaaaaggatttcagaaaacaagtcaactatgag
gtggatcagagatttcatagagaattccctaaatttttcacattccgagcaagagataag
tttgaggaggatcgtatctatcgtcacttggagcctgccctggctttccagttagagttg
aaccgaatgaggaattttgacctcactgccattccatgtgctaatcacaagatgcatctg
tatcttggagcagccaaagtcgaagtaggcacagaagtgacagattataggttctttgtt
cgcgcaatcatcagacattctgatctggtcaccaaggaagcttcttttgagtatctacaa
aatgaaggggaacggttactcctagaagcaatggatgagttggaggtcgctttcaacaat
acaaatgttcgcactgactgcaaccacatctttctcaactttgttcccacagtcatcatg
gacccatcaaagattgaggaatctgtgcggagcatggtgatgcgctatggaagccgactg
tggaaattacgcgtcctccaggcagaactgaagatcaacattcgcctgacaccaactgga
aaagcaattcccattcgcctcttcctgacaaacgagtctggctattacttggacatcagc
ctatacaaagaagtgactgactccagaacagcacagatcatgtttcaagcatatggagac
aaacagggaccattgcatggaatgttaatcaatactccgtatgtgaccaaagatctgctt
caatctaagaggtttcaagcacagtccctaggaacaacatacatatacgatattccagag
atgtttcggcagtccctgatcaaactgtgggagtctatgtccgctcaggcattccttcca
tcaccccctttgccttctgacatgctgacatacactgaacttgtcctggatgatcaaggc
caattggtccacatgaacaggcttccgggaggaaatgagattggcatggtagcctggaaa
atgacccttaaaagtcctgaatatccagaaggccgagatatcattgttattggaaatgac
atcacctaccgaattggatcctttggaccccaggaggatttgctgtttctcagagcttct
gagcttgccagggcagaggggatccctcgtatctatgtagcagccaacagtggagcaaga
attggactggctgaggaaattcgtcatatgtttcatgtggcctgggtagatcctgaggat
ccttacaagggatacaagtatctgtacctgacccctcaggattataagagagtcagtgct
ctcaactctgtctattgtgagcatgtggaggatgaaggggaatccaggtacaagataact
gatattattggaaaggaagagggacttggagcagagaaccttcgaggttctggaatgatt
gctggagaatcctcattggcctatgatgagatcatcactatcagcttggttacatgccgg
gccattggaattggggcttaccttgttcgactgggacagagaaccatccaggttgagaat
tctcacttaattcttacaggagccggcgctctcaataaagttcttgggcgggaggtgtat
acctccaataaccagctcgggggcatccagatcatgcacaacaatggcgtcacccacagc
accgtctgtgatgacttcgagggggtgttcacaatcctgcactggctgtcttatatgcct
aagagcgttcacagttctgttcctctcctgaactccaaggatccaattgatagaatcatc
gagtttgttcccacaaaggccccgtatgatccccgctggatgctagccggccgtcctcac
ccaactcaaaaaggtcagtggctgagtggattttttgactacggctctttctcagagatc
atgcaaccctgggcccagaccgtggtagtgggcagagccaggctaggaggaatacctgtg
ggagtagttgctgtagaaacgcgaactgtggagctcagtattccagctgatcctgcaaac
ctggattctgaagcgaagataatccagcaggctggtcaagtttggttcccagactctgca
tttaagacatttcaagctatcaaggacttcaaccgtgaagggctacctttgatggtcttt
gctaactggaggggcttctctggtggaatgaaagacatgtacgaccaggtgctgaagttt
ggcgcttacatcgtggatggcctacgggagtgctctcagcccgtgatggtttacattcct
ccgcaggctgaactgcgcggtggctcctgggtggtgattgaccccactatcaaccctcgg
cacatggagatgtacgccgaccgagaaagcaggggatcagttctggagcctgaagggaca
gtagaaatcaaattccgcaaaaaggatctggtgaaaaccatgcgtcgggtggacccagtc
tatatccacttggctgagcgattgggcaccccggagttaagtgcagctgagcggaaggag
ctagagaacaagttgaaggagcgggaggaattcctaattcccatttaccatcaggtggcc
gtgcagtttgctgacttgcacgacacgccgggccgcatgcaggaaaagggtgttattaac
gacatccttgattggaaaacatcccgaaccttcttctactggcggttgaggcggctcctg
ctggaagatctggtcaagaagaaaatccataatgccaaccccgaactgacagatggccag
atccaggccatgttgagacgctggtttgtggaagtggaaggaacggtaaaggcctatgtt
tgggacaataacaaggatctggtggagtggctggagaagcagctgactgaggaagatggc
gtccgctcagtaattgaggaaaacatcaaatacatcagcagagactatgtcctcaagcag
atccgcagtttggtccaggccaatcccgaagttgccatggattccatcgtccatatgacc
caacacatctcacccactcagcgagcagaagttgtccggatcctttctacgatggattcc
ccttcaacgtag
DBGET
integrated database retrieval system
