Sorex araneus (European shrew): 101551961 Help Entry 101551961         CDS       T07854                                  Symbol PRKCA Name (RefSeq) protein kinase C alpha type   KO K02677   classical protein kinase C alpha type [EC:2.7.11.13] Organism sara  Sorex araneus (European shrew) Pathway sara01521   EGFR tyrosine kinase inhibitor resistance sara04010   MAPK signaling pathway sara04012   ErbB signaling pathway sara04014   Ras signaling pathway sara04015   Rap1 signaling pathway sara04020   Calcium signaling pathway sara04066   HIF-1 signaling pathway sara04070   Phosphatidylinositol signaling system sara04071   Sphingolipid signaling pathway sara04072   Phospholipase D signaling pathway sara04150   mTOR signaling pathway sara04151   PI3K-Akt signaling pathway sara04261   Adrenergic signaling in cardiomyocytes sara04270   Vascular smooth muscle contraction sara04310   Wnt signaling pathway sara04360   Axon guidance sara04370   VEGF signaling pathway sara04510   Focal adhesion sara04540   Gap junction sara04613   Neutrophil extracellular trap formation sara04650   Natural killer cell mediated cytotoxicity sara04664   Fc epsilon RI signaling pathway sara04666   Fc gamma R-mediated phagocytosis sara04670   Leukocyte transendothelial migration sara04713   Circadian entrainment sara04720   Long-term potentiation sara04723   Retrograde endocannabinoid signaling sara04724   Glutamatergic synapse sara04725   Cholinergic synapse sara04726   Serotonergic synapse sara04727   GABAergic synapse sara04728   Dopaminergic synapse sara04730   Long-term depression sara04750   Inflammatory mediator regulation of TRP channels sara04911   Insulin secretion sara04912   GnRH signaling pathway sara04916   Melanogenesis sara04918   Thyroid hormone synthesis sara04919   Thyroid hormone signaling pathway sara04921   Oxytocin signaling pathway sara04925   Aldosterone synthesis and secretion sara04926   Relaxin signaling pathway sara04928   Parathyroid hormone synthesis, secretion and action sara04929   GnRH secretion sara04933   AGE-RAGE signaling pathway in diabetic complications sara04935   Growth hormone synthesis, secretion and action sara04960   Aldosterone-regulated sodium reabsorption sara04961   Endocrine and other factor-regulated calcium reabsorption sara04970   Salivary secretion sara04971   Gastric acid secretion sara04972   Pancreatic secretion sara05017   Spinocerebellar ataxia sara05022   Pathways of neurodegeneration - multiple diseases sara05031   Amphetamine addiction sara05032   Morphine addiction sara05143   African trypanosomiasis sara05146   Amoebiasis sara05161   Hepatitis B sara05163   Human cytomegalovirus infection sara05164   Influenza A sara05170   Human immunodeficiency virus 1 infection sara05171   Coronavirus disease - COVID-19 sara05200   Pathways in cancer sara05205   Proteoglycans in cancer sara05206   MicroRNAs in cancer sara05207   Chemical carcinogenesis - receptor activation sara05214   Glioma sara05223   Non-small cell lung cancer sara05225   Hepatocellular carcinoma sara05231   Choline metabolism in cancer sara05415   Diabetic cardiomyopathy sara05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:sara00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101551961 (PRKCA)    04012 ErbB signaling pathway     101551961 (PRKCA)    04014 Ras signaling pathway     101551961 (PRKCA)    04015 Rap1 signaling pathway     101551961 (PRKCA)    04310 Wnt signaling pathway     101551961 (PRKCA)    04370 VEGF signaling pathway     101551961 (PRKCA)    04066 HIF-1 signaling pathway     101551961 (PRKCA)    04020 Calcium signaling pathway     101551961 (PRKCA)    04070 Phosphatidylinositol signaling system     101551961 (PRKCA)    04072 Phospholipase D signaling pathway     101551961 (PRKCA)    04071 Sphingolipid signaling pathway     101551961 (PRKCA)    04151 PI3K-Akt signaling pathway     101551961 (PRKCA)    04150 mTOR signaling pathway     101551961 (PRKCA)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     101551961 (PRKCA)    04540 Gap junction     101551961 (PRKCA)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     101551961 (PRKCA)    04650 Natural killer cell mediated cytotoxicity     101551961 (PRKCA)    04664 Fc epsilon RI signaling pathway     101551961 (PRKCA)    04666 Fc gamma R-mediated phagocytosis     101551961 (PRKCA)    04670 Leukocyte transendothelial migration     101551961 (PRKCA)   09152 Endocrine system    04911 Insulin secretion     101551961 (PRKCA)    04929 GnRH secretion     101551961 (PRKCA)    04912 GnRH signaling pathway     101551961 (PRKCA)    04921 Oxytocin signaling pathway     101551961 (PRKCA)    04926 Relaxin signaling pathway     101551961 (PRKCA)    04935 Growth hormone synthesis, secretion and action     101551961 (PRKCA)    04918 Thyroid hormone synthesis     101551961 (PRKCA)    04919 Thyroid hormone signaling pathway     101551961 (PRKCA)    04928 Parathyroid hormone synthesis, secretion and action     101551961 (PRKCA)    04916 Melanogenesis     101551961 (PRKCA)    04925 Aldosterone synthesis and secretion     101551961 (PRKCA)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     101551961 (PRKCA)    04270 Vascular smooth muscle contraction     101551961 (PRKCA)   09154 Digestive system    04970 Salivary secretion     101551961 (PRKCA)    04971 Gastric acid secretion     101551961 (PRKCA)    04972 Pancreatic secretion     101551961 (PRKCA)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     101551961 (PRKCA)    04961 Endocrine and other factor-regulated calcium reabsorption     101551961 (PRKCA)   09156 Nervous system    04724 Glutamatergic synapse     101551961 (PRKCA)    04727 GABAergic synapse     101551961 (PRKCA)    04725 Cholinergic synapse     101551961 (PRKCA)    04728 Dopaminergic synapse     101551961 (PRKCA)    04726 Serotonergic synapse     101551961 (PRKCA)    04720 Long-term potentiation     101551961 (PRKCA)    04730 Long-term depression     101551961 (PRKCA)    04723 Retrograde endocannabinoid signaling     101551961 (PRKCA)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     101551961 (PRKCA)   09158 Development and regeneration    04360 Axon guidance     101551961 (PRKCA)   09159 Environmental adaptation    04713 Circadian entrainment     101551961 (PRKCA)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101551961 (PRKCA)    05206 MicroRNAs in cancer     101551961 (PRKCA)    05205 Proteoglycans in cancer     101551961 (PRKCA)    05207 Chemical carcinogenesis - receptor activation     101551961 (PRKCA)    05231 Choline metabolism in cancer     101551961 (PRKCA)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     101551961 (PRKCA)    05214 Glioma     101551961 (PRKCA)    05223 Non-small cell lung cancer     101551961 (PRKCA)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     101551961 (PRKCA)    05161 Hepatitis B     101551961 (PRKCA)    05171 Coronavirus disease - COVID-19     101551961 (PRKCA)    05164 Influenza A     101551961 (PRKCA)    05163 Human cytomegalovirus infection     101551961 (PRKCA)   09174 Infectious disease: parasitic    05146 Amoebiasis     101551961 (PRKCA)    05143 African trypanosomiasis     101551961 (PRKCA)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     101551961 (PRKCA)    05022 Pathways of neurodegeneration - multiple diseases     101551961 (PRKCA)   09165 Substance dependence    05031 Amphetamine addiction     101551961 (PRKCA)    05032 Morphine addiction     101551961 (PRKCA)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     101551961 (PRKCA)    05415 Diabetic cardiomyopathy     101551961 (PRKCA)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     101551961 (PRKCA)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     101551961 (PRKCA)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:sara01001]     101551961 (PRKCA)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:sara04131]     101551961 (PRKCA) Enzymes [BR:sara01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      101551961 (PRKCA) Protein kinases [BR:sara01001]  Serine/threonine kinases: AGC group   PKC family [OT]    101551961 (PRKCA) Membrane trafficking [BR:sara04131]  Endocytosis   Lipid raft mediated endocytosis    Caveolin-mediated endocytosis     101551961 (PRKCA) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C C1_2 ABC1 DUF4656 Motif Other DBs NCBI-GeneID:  101551961 NCBI-ProteinID:  XP_004618040 LinkDB All DBs Position Unknown AA seq 668 aa AA seqDB search MADVFPANDSPATQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTEEKLHVTVRDA KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNAE LRQKFEKAKLGPAGNKAASSSEERRQPSNNLDRVKLSDFNFLMVLGKGSFGKVMLADRKG TEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYV NGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDAEGHIKIA DFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDG EDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPGKRLGCGPEGERDVREHAFFRRI DWEKLESREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVN PQFVQSAV NT seq 2007 nt NT seq  +upstreamnt  +downstreamnt atggctgacgttttcccggccaacgactccccggcgacccaggacgtggccaaccgcttc gcccgcaaaggggcgctgaggcagaagaacgtgcacgaggtgaaggaccacaaattcatc gcgcgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt ggaaaacaaggcttccagtgccaagtttgctgttttgtggttcacaagaggtgccatgaa tttgttacgttttcctgcccgggtgcggataagggacccgacacggatgacccccggagc aagcacaagttcaagatccacacgtacgggagcccgaccttctgcgaccactgtggctct ctgctgtacggcctcatccaccaaggcatgaagtgcgacacctgcgacatgaacgtgcac aagcagtgcgtcatcaacgtgcccagcctctgcggcatggaccacacggagaagaggggc cgaatctacctgaaggccgaggtcaccgaggagaagctgcacgtcacagtccgagacgcg aaaaatctaatccccatggacccgaatgggctttcagacccttacgtgaagctgaaactg attccggaccccaagaacgagagcaagcagaaaaccaaaaccatccgctccacgctgaac ccccagtggaacgagtccttcaccttcaagttgaaaccttccgacaaagaccgccggctg tccgtcgagatctgggactgggaccggaccaccaggaacgacttcatgggctccctgtcc ttcggcgtgtctgagctcatgaagatgcccgccagcggatggtacaagctgctgaaccag gaggaaggggagtactacaacgtgcccatcccggaaggggacgaggaagggaacgcagag ctgcggcagaaattcgagaaagccaagctgggccccgcggggaacaaggcggccagctcg tcggaggagcgcagacagccgtccaacaacctggacagagtcaagctctcggacttcaac ttcctcatggttctggggaaggggagcttcgggaaggtgatgctggccgacaggaagggc accgaggagctgtacgccatcaagatcctcaagaaggacgtggtgatccaggacgacgac gtggagtgcaccatggtggagaagcgggtgctggcgctgctggacaagccgcccttcctc acgcagctgcactcctgcttccagacagtggaccggctgtacttcgtcatggaatacgtc aatggcggggacctcatgtaccacatccagcaagtcggcaagttcaaggagccacaggca gtattctacgcagccgagatttccatcgggttgttcttcctgcacaaacgaggtatcatt tatagggacctgaagttggacaatgtcatgctggacgcggagggacacatcaagatcgcc gacttcggcatgtgcaaggagcacatgatggacggggtcacgaccagaaccttctgcggg actccggattacatcgcccctgagatcatcgcttatcagccctatggaaaatctgtggac tggtgggcctacggcgtcctgttgtatgagatgctggcgggacagcctccgtttgacggc gaagatgaagacgaactgttccagtccatcatggaacataacgtgtcctaccccaagtcc ctgtccaaggaggcggtctccatctgcaagggactgatgaccaagcacccgggcaagcgg ctgggctgcgggcccgagggcgagcgggacgtgcgtgaacacgccttcttccggaggatc gactgggagaagctggagagcagggagatccagccgcccttcaagcccaaagtgtgcggc aaaggagcggaaaattttgacaagttcttcacccgaggacagccggtcctgaccccgccg gaccagctggtcatcgctaacattgaccagtctgatttcgaggggttctcctatgtcaac ccccagttcgtgcagagcgcagtatga

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