Streptomyces argyrophyllae: HKX69_33740
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Entry
HKX69_33740 CDS
T09378
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
sarg
Streptomyces argyrophyllae
Pathway
sarg00010
Glycolysis / Gluconeogenesis
sarg00020
Citrate cycle (TCA cycle)
sarg00620
Pyruvate metabolism
sarg00785
Lipoic acid metabolism
sarg01100
Metabolic pathways
sarg01110
Biosynthesis of secondary metabolites
sarg01120
Microbial metabolism in diverse environments
sarg01200
Carbon metabolism
sarg01210
2-Oxocarboxylic acid metabolism
Module
sarg_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sarg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
HKX69_33740 (pdhA)
00020 Citrate cycle (TCA cycle)
HKX69_33740 (pdhA)
00620 Pyruvate metabolism
HKX69_33740 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HKX69_33740 (pdhA)
Enzymes [BR:
sarg01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
HKX69_33740 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
QJS14752
UniProt:
A0A6M4PUU3
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Position
7505467..7506414
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AA seq
315 aa
AA seq
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MLESMLRVRRFEERCVELYSAARIRGFMHLYIGEEAVAVGVTEALTADDAVVSTYREHGH
ALARGVPAEAIMAEMFGKVTGCSRGRGGSMHLFDAGRRFYGGNAIVGGGLPLAAGLALAD
RMTGRNRVTCCFFGDGAFAEGEFHETANLAALWGLPLLLVCENNLYAMGTALARHQAQTD
LALRAAGYGMVSWAVDGMDVFAVEDAARRAAEGVRAGTGPHFLEMRTYRFRAHSMYDPDR
YRDKTEIEHWKERDPVEGLARRLREAKELTDKARTALEDRLAAEIDRAVEAADQAPEEPV
EDLLKYVTSPEASRP
NT seq
948 nt
NT seq
+upstream
nt +downstream
nt
ctgctggagtcgatgctgcgcgtccgccggttcgaggagcgctgcgtggagctgtacagc
gccgcccgcatccggggtttcatgcacctctacatcggtgaggaagccgtggccgtcggc
gtgaccgaggcactcacggccgacgacgcggtcgtgtcgacttaccgcgaacacgggcac
gcactggcccgcggggttccggccgaggcgatcatggcggagatgttcggcaaggtgacc
ggttgtagccgcggccgtggcggctcgatgcaccttttcgacgccggccgccgcttctac
ggcggcaacgcgatcgtcggcggtgggcttccgctcgcggccggcctggccctcgccgac
cgcatgaccggccgcaatcgtgtcacctgctgcttcttcggcgacggcgcctttgccgag
ggcgagttccacgagaccgccaacctcgccgcgctgtgggggctgccgctgctgctggtc
tgcgagaacaacctgtacgcgatgggcaccgccctggcccggcaccaggcccagaccgac
ctcgcgctgcgtgccgccgggtacggcatggtctcctgggccgtcgacggcatggacgtc
ttcgccgtggaggacgccgcccggcgggcggccgaaggcgtacgcgccggaaccggaccg
cacttcctggagatgcgcacgtaccgcttccgcgcccactccatgtacgaccctgaccgc
taccgcgacaagaccgagatcgagcactggaaggaacgcgacccggtcgaagggctcgcc
cggcgactgcgggaggcgaaggagctgaccgacaaggcccgcaccgccctggaggaccgc
ctggccgccgagatcgaccgcgccgtcgaggccgccgatcaggctcccgaggaacccgtc
gaggatctgctgaagtacgtcaccagcccggaggcgagccggccatga
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