Staphylococcus aureus USA300-ISMMS1 (MRSA): AZ30_05220
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Entry
AZ30_05220 CDS
T03115
Name
(GenBank) pyruvate dehydrogenase E1 subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
saui
Staphylococcus aureus USA300-ISMMS1 (MRSA)
Pathway
saui00010
Glycolysis / Gluconeogenesis
saui00020
Citrate cycle (TCA cycle)
saui00620
Pyruvate metabolism
saui00785
Lipoic acid metabolism
saui01100
Metabolic pathways
saui01110
Biosynthesis of secondary metabolites
saui01120
Microbial metabolism in diverse environments
saui01200
Carbon metabolism
saui01210
2-Oxocarboxylic acid metabolism
Module
saui_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
saui00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
AZ30_05220
00020 Citrate cycle (TCA cycle)
AZ30_05220
00620 Pyruvate metabolism
AZ30_05220
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AZ30_05220
Enzymes [BR:
saui01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
AZ30_05220
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
AHJ06819
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Position
1108248..1109360
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AA seq
370 aa
AA seq
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MAPKLQAQFDAVKVLNDTQSKFEMVQILDENGNVVNEDLVPDLTDEQLVELMERMVWTRI
LDQRSISLNRQGRLGFYAPTAGQEASQLASQYALEKEDYILPGYRDVPQIIWHGLPLTEA
FLFSRGHFKGNQFPEGVNALSPQIIIGAQYIQAAGVAFALKKRGKNAVAITYTGDGGSSQ
GDFYEGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDA
LAVYQATKEARDRAVAGEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWEKKDPLVR
FRKFLENKGLWNEDKENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYEDMPQNLAEQ
YEIYKEKESK
NT seq
1113 nt
NT seq
+upstream
nt +downstream
nt
atggctcctaagttacaagcccaattcgatgcagtaaaagttttaaatgatactcaatcg
aaatttgaaatggttcaaattttggatgagaatggtaacgtcgtaaatgaagacttagta
cctgatcttacggatgaacaattagtggaattaatggaaagaatggtatggactcgtatc
cttgatcaacgttctatctcattaaacagacaaggacgtttaggtttctatgcaccaact
gctggtcaagaagcatcacaattagcgtcacaatacgctttagaaaaagaagattacatt
ttaccgggatacagagatgttcctcaaattatttggcatggtttaccattaactgaagct
ttcttattctcaagaggtcacttcaaaggaaatcaattccctgaaggcgttaatgcatta
agcccacaaattattatcggtgcacaatacattcaagctgctggtgttgcatttgcactt
aaaaaacgtggtaaaaatgcagttgcaatcacttacactggtgacggtggttcttcacaa
ggtgatttctacgaaggtattaactttgcagcagcttataaagcacctgcaattttcgtt
attcaaaacaataactatgcaatttcaacaccaagaagcaagcaaactgctgctgaaaca
ttagctcaaaaagcaattgctgtaggtattcctggtatccaagttgatggtatggatgcg
ttagctgtatatcaagcaactaaagaagcacgtgaccgcgcagttgcaggtgaaggtcca
acattaattgaaactatgacatatcgttatggtcctcatacaatggctggtgacgatcca
actcgttacagaacttcagacgaagatgctgaatgggagaaaaaagacccattagtacgt
ttccgtaaattccttgaaaacaaaggtttatggaatgaagacaaagaaaatgaagttatt
gaacgtgcaaaagctgatattaaagcagcaattaaagaggctgataacactgaaaaacaa
actgttacttctctaatggaaattatgtatgaagatatgcctcaaaacttagcagaacaa
tatgaaatttacaaagagaaggagtcgaagtaa
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