Staphylococcus aureus subsp. aureus Mu50 (MRSA/VISA): SAV1093
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Entry
SAV1093 CDS
T00052
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase E1 component alpha subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
sav
Staphylococcus aureus subsp. aureus Mu50 (MRSA/VISA)
Pathway
sav00010
Glycolysis / Gluconeogenesis
sav00020
Citrate cycle (TCA cycle)
sav00620
Pyruvate metabolism
sav00785
Lipoic acid metabolism
sav01100
Metabolic pathways
sav01110
Biosynthesis of secondary metabolites
sav01120
Microbial metabolism in diverse environments
sav01200
Carbon metabolism
sav01210
2-Oxocarboxylic acid metabolism
Module
sav_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sav00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SAV1093 (pdhA)
00020 Citrate cycle (TCA cycle)
SAV1093 (pdhA)
00620 Pyruvate metabolism
SAV1093 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SAV1093 (pdhA)
Enzymes [BR:
sav01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SAV1093 (pdhA)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
BAB57255
UniProt:
P60089
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All DBs
Position
1147170..1148282
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AA seq
370 aa
AA seq
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MAPKLQAQFDAVKVLNDTQSKFEMVQILDENGNVVNEDLVPDLTDEQLVELMERMVWTRI
LDQRSISLNRQGRLGFYAPTAGQEASQLASQYALEKEDYILPGYRDVPQIIWHGLPLTEA
FLFSRGHFKGNQFPEGVNALSPQIIIGAQYIQAAGVAFALKKRGKNAVAITYTGDGGSSQ
GDFYEGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDA
LAVYQATKEARDRAVAGEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWEKKDPLVR
FRKFLENKGLWNEDKENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYEDMPQNLAEQ
YEIYKEKESK
NT seq
1113 nt
NT seq
+upstream
nt +downstream
nt
atggctcctaagttacaagcccaattcgatgcagtaaaagttttaaatgatactcaatcg
aaatttgaaatggttcaaattttggatgagaatggtaacgtcgtaaatgaagacttagta
cctgatcttacggatgaacaattagtagaattaatggaaagaatggtatggactcgtatc
cttgatcaacgttctatctcattaaacagacaaggacgtttaggtttctatgcaccaact
gctggtcaagaagcatcacaattagcgtcacaatacgctttagaaaaagaagattacatt
ttaccgggatacagagatgttcctcaaattatttggcatggtttaccattaactgaagct
ttcttattctcaagaggtcacttcaaaggaaatcaattccctgaaggcgttaatgcattg
agcccacaaattattatcggtgcacaatacattcaagctgctggtgttgcatttgcactt
aaaaaacgtggtaaaaatgcagttgcaatcacttacactggtgacggtggttcttcacaa
ggtgatttctacgaaggtattaactttgcagcagcttataaagcacctgcaattttcgtt
attcaaaacaataactatgcaatttcaacaccaagaagcaagcaaactgctgctgaaaca
ttagctcaaaaagcaattgctgtaggtattcctggtatccaagttgatggtatggatgcg
ttagctgtatatcaagcaactaaagaagcacgtgaccgcgcagttgcaggtgaaggtcca
acattaattgaaactatgacatatcgttatggtcctcatacaatggctggtgacgatcca
actcgttacagaacttcagacgaagatgctgaatgggagaaaaaagacccattagtacgt
ttccgtaaattccttgaaaacaaaggtttatggaatgaagacaaagaaaatgaagttatt
gaacgtgcaaaagctgatattaaagcagcaattaaagaggctgataacactgaaaaacaa
actgttacttctctaatggaaattatgtatgaagatatgcctcaaaacttagcagaacaa
tatgaaatttacaaagagaaggagtcgaagtaa
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