KEGG   Saimiri boliviensis boliviensis (Bolivian squirrel monkey): 101040899
Entry
101040899         CDS       T04350                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
sbq  Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
Pathway
sbq01522  Endocrine resistance
sbq04010  MAPK signaling pathway
sbq04015  Rap1 signaling pathway
sbq04068  FoxO signaling pathway
sbq04071  Sphingolipid signaling pathway
sbq04114  Oocyte meiosis
sbq04148  Efferocytosis
sbq04218  Cellular senescence
sbq04261  Adrenergic signaling in cardiomyocytes
sbq04370  VEGF signaling pathway
sbq04380  Osteoclast differentiation
sbq04550  Signaling pathways regulating pluripotency of stem cells
sbq04611  Platelet activation
sbq04613  Neutrophil extracellular trap formation
sbq04620  Toll-like receptor signaling pathway
sbq04621  NOD-like receptor signaling pathway
sbq04622  RIG-I-like receptor signaling pathway
sbq04625  C-type lectin receptor signaling pathway
sbq04657  IL-17 signaling pathway
sbq04658  Th1 and Th2 cell differentiation
sbq04659  Th17 cell differentiation
sbq04660  T cell receptor signaling pathway
sbq04664  Fc epsilon RI signaling pathway
sbq04668  TNF signaling pathway
sbq04670  Leukocyte transendothelial migration
sbq04714  Thermogenesis
sbq04722  Neurotrophin signaling pathway
sbq04723  Retrograde endocannabinoid signaling
sbq04728  Dopaminergic synapse
sbq04750  Inflammatory mediator regulation of TRP channels
sbq04912  GnRH signaling pathway
sbq04914  Progesterone-mediated oocyte maturation
sbq04917  Prolactin signaling pathway
sbq04926  Relaxin signaling pathway
sbq04932  Non-alcoholic fatty liver disease
sbq04933  AGE-RAGE signaling pathway in diabetic complications
sbq04935  Growth hormone synthesis, secretion and action
sbq04936  Alcoholic liver disease
sbq05014  Amyotrophic lateral sclerosis
sbq05020  Prion disease
sbq05022  Pathways of neurodegeneration - multiple diseases
sbq05132  Salmonella infection
sbq05133  Pertussis
sbq05135  Yersinia infection
sbq05140  Leishmaniasis
sbq05142  Chagas disease
sbq05145  Toxoplasmosis
sbq05152  Tuberculosis
sbq05161  Hepatitis B
sbq05163  Human cytomegalovirus infection
sbq05167  Kaposi sarcoma-associated herpesvirus infection
sbq05169  Epstein-Barr virus infection
sbq05170  Human immunodeficiency virus 1 infection
sbq05171  Coronavirus disease - COVID-19
sbq05205  Proteoglycans in cancer
sbq05208  Chemical carcinogenesis - reactive oxygen species
sbq05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
sbq05415  Diabetic cardiomyopathy
sbq05417  Lipid and atherosclerosis
sbq05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:sbq00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101040899 (MAPK12)
   04015 Rap1 signaling pathway
    101040899 (MAPK12)
   04370 VEGF signaling pathway
    101040899 (MAPK12)
   04668 TNF signaling pathway
    101040899 (MAPK12)
   04068 FoxO signaling pathway
    101040899 (MAPK12)
   04071 Sphingolipid signaling pathway
    101040899 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    101040899 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    101040899 (MAPK12)
   04218 Cellular senescence
    101040899 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    101040899 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101040899 (MAPK12)
   04613 Neutrophil extracellular trap formation
    101040899 (MAPK12)
   04620 Toll-like receptor signaling pathway
    101040899 (MAPK12)
   04621 NOD-like receptor signaling pathway
    101040899 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    101040899 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    101040899 (MAPK12)
   04660 T cell receptor signaling pathway
    101040899 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    101040899 (MAPK12)
   04659 Th17 cell differentiation
    101040899 (MAPK12)
   04657 IL-17 signaling pathway
    101040899 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    101040899 (MAPK12)
   04670 Leukocyte transendothelial migration
    101040899 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    101040899 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    101040899 (MAPK12)
   04917 Prolactin signaling pathway
    101040899 (MAPK12)
   04926 Relaxin signaling pathway
    101040899 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    101040899 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101040899 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    101040899 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    101040899 (MAPK12)
   04722 Neurotrophin signaling pathway
    101040899 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101040899 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101040899 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    101040899 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    101040899 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    101040899 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101040899 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101040899 (MAPK12)
   05161 Hepatitis B
    101040899 (MAPK12)
   05171 Coronavirus disease - COVID-19
    101040899 (MAPK12)
   05163 Human cytomegalovirus infection
    101040899 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101040899 (MAPK12)
   05169 Epstein-Barr virus infection
    101040899 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101040899 (MAPK12)
   05135 Yersinia infection
    101040899 (MAPK12)
   05133 Pertussis
    101040899 (MAPK12)
   05152 Tuberculosis
    101040899 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101040899 (MAPK12)
   05140 Leishmaniasis
    101040899 (MAPK12)
   05142 Chagas disease
    101040899 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101040899 (MAPK12)
   05020 Prion disease
    101040899 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    101040899 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101040899 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    101040899 (MAPK12)
   05415 Diabetic cardiomyopathy
    101040899 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101040899 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    101040899 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101040899 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101040899 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:sbq01001]
    101040899 (MAPK12)
Enzymes [BR:sbq01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     101040899 (MAPK12)
Protein kinases [BR:sbq01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   101040899 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo Kinase-like Haspin_kinase
Other DBs
NCBI-GeneID: 101040899
NCBI-ProteinID: XP_003932826
UniProt: A0A2K6SM66
LinkDB
Position
Unknown
AA seq 367 aa
MSSPPPARSGFYRQEVTKTVWEVRVVYRDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHEKLGEDRIQFLVYQMLKGLKYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMK
VTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRV
TAAEALAHPYFESLHETEDEPQAQKYDDSFDDVDRTLDEWKRVTYKEVLSFKPPRQLGAR
VSKETAL
NT seq 1104 nt   +upstreamnt  +downstreamnt
atgagctctccgccgcccgcccgtagtggcttttaccgccaggaggtgaccaagacggtc
tgggaggtgcgcgtcgtgtaccgggatctgcagcccgtgggctcgggcgcctatggcgcg
gtgtgctccgcggtggacagccgcaccggcgccaaggtggccatcaagaagctgtaccgg
cccttccagtccgagctgttcgccaagcgcgcctaccgcgagctgcgcctgctcaagcac
atgcgccacgagaacgtgatcgggctgctggacgtattcactcctgacgagaccctggat
gacttcacggacttttacctggtgatgccattcatgggcactgacctagggaagctcatg
aagcacgagaagctgggagaggaccggatccagttcctcgtgtaccagatgctgaagggg
ctgaagtatatccacgctgccggcatcatccacagagatctgaagcccggcaacctggct
gtgaacgaagactgtgagctgaagatcctggactttggcctggccaggcaggccgacagc
gagatgactgggtatgtggtgactcggtggtaccgggcacccgaggtcatcttgaattgg
atgcgctacacacagacggtggacatctggtctgtgggctgcatcatggcagagatgatc
acaggcaagacattgttcaagggcagtgaccacctggaccagctgaaggagatcatgaag
gtgacagggacgcctccagctgagtttgtgcagcggctgcagagcgatgaggctaagaac
tacatgaagggcctccctgagttggagaagaaggattttgcctccatcctgaccaatgca
agccctctggctgtgaacctcctggagaagatgctggtgctggatgcggagcagcgggtg
acagcagccgaggcgctggctcacccctactttgagtccctgcatgagacggaagatgag
ccccaggcccagaagtatgatgactcctttgatgatgtggaccgcacactggatgaatgg
aagcgtgtcacatacaaagaagtgctcagcttcaagcctccccggcagctgggggccagg
gtctccaaggagacggctctgtga

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