Streptomyces broussonetiae: GQF42_16635
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Entry
GQF42_16635 CDS
T07359
Name
(GenBank) dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sbro
Streptomyces broussonetiae
Pathway
sbro00790
Folate biosynthesis
sbro01100
Metabolic pathways
sbro01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sbro00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
GQF42_16635
Enzymes [BR:
sbro01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
GQF42_16635
6.3.2.17 tetrahydrofolate synthase
GQF42_16635
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QHA04702
UniProt:
A0A6I6MZF5
LinkDB
All DBs
Position
complement(3586412..3587926)
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AA seq
504 aa
AA seq
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MSDLPDENDQPDPLGSFEEIIEAETTRDPDLAVIEAGSRTLRTQGGAPQADVPGRPEDPE
VDKALREVEAELATRWGETKLEPSVSRITALMDLLGEPQRSYPSIHITGTNGKTSTARMI
EALLGAFELRTGRYTSPHVQSITERISLDGAPVSAERFIETYQDIKPYIEMVDAAQEYRL
SFFEVLTGMAYAAFADAPVDVAVVEVGMGGSWDATNVIDGDVAVITPIDLDHTDRLGETT
AEIAVEKSGIIKQGATVILSQQPVDAAQVLLKKAVEVDATVAREGLEFGVVAREVAVGGQ
LLTLRGLGGEYPEVYLPLHGAHQAHNAAVALAAVEAFFGVGAQRAESLDIDTVRKAFAAV
SSPGRLEVVRRSPTVVLDAAHNPAGAAATTEAVREAFDFTRLIGVVGASGDKNVRGLLEA
FEPIFAEVVVTQNSTPRAMDADELAAIAVEVFGEERVQVEPRLPDALEAAITLAEEEGEF
AGGGVLVTGSVITVGEARLLLGKG
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgacctcccggacgagaacgaccagcccgaccccctcggcagcttcgaggagatc
atcgaagccgagaccacccgcgaccccgacctcgcggtgatcgaggccggcagccgcacc
ctgcgcacgcagggcggcgcgccgcaggccgacgtacccgggcggcccgaggaccccgag
gtcgacaaggccctgcgcgaggtcgaggcggagctggccacccgctggggcgagaccaag
ctggagccgtcggtcagccgtatcaccgcgctgatggacctgctgggcgagccgcagcgg
tcgtacccgtcgatccacatcaccggcacgaacggcaagacctccaccgcccgcatgatc
gaggccctgctcggcgccttcgagctgcgcaccggccgctacaccagcccccatgtgcag
tcgatcaccgagcggatcagcctggacggcgccccggtctccgccgagcggttcatcgag
acctaccaggacatcaagccgtacatcgagatggtggacgccgctcaggagtaccgcctg
tccttcttcgaggtgctcaccggcatggcgtacgcggccttcgcggacgcccccgtggac
gtcgccgtcgtcgaggtcggcatgggcggctcctgggacgccaccaacgtcatcgacggc
gacgtcgccgtgatcaccccgatcgacctggaccacaccgaccggctcggcgagacgacc
gcggagatcgccgtcgagaagagcgggatcatcaagcagggcgcgacggtgatcctgtcg
cagcagccggtcgacgcggcgcaggtgctgctgaagaaggccgtcgaggtggacgcgacc
gtggcccgcgaggggctggagttcggggtcgtggcgcgggaggtcgccgtcggcgggcag
ttgctcaccctgcgcggtctcggtggcgagtaccccgaggtgtatctcccgctgcacggc
gcccatcaggcgcacaacgcggccgtcgcgctcgccgccgtcgaggcgttcttcggcgtc
ggcgcgcagcgcgcggagtcgctcgacatcgacaccgtccgcaaggccttcgcggccgtg
tcctccccgggccggctggaggtcgtacggcgttccccgaccgtcgtgctggacgcggcg
cacaacccggcgggcgccgcggccaccacggaggcggtgcgggaggcgttcgacttcacc
cggctgatcggtgtggtgggtgcgagcggcgacaagaacgtgcgggggctgctggaggcc
ttcgagccgatcttcgccgaggtcgtcgtcacgcagaactccaccccgcgggccatggac
gcggacgagctggccgcgatcgccgtcgaggtgttcggcgaggagcgggtgcaggtcgag
ccgcggctgccggacgccctggaggccgcgatcacgctggccgaggaggagggcgagttc
gcgggcggtggcgtactggtcaccggatctgtcattacagtcggcgaggcccggctgctg
ctggggaagggctga
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