Streptomyces californicus: I6J39_10290
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Entry
I6J39_10290 CDS
T07611
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
scal
Streptomyces californicus
Pathway
scal00790
Folate biosynthesis
scal01100
Metabolic pathways
scal01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
scal00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
I6J39_10290
Enzymes [BR:
scal01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
I6J39_10290
6.3.2.17 tetrahydrofolate synthase
I6J39_10290
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QRV27664
LinkDB
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Position
complement(2314388..2315908)
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AA seq
506 aa
AA seq
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MSEPRPDRHDEPDPDETFEGIVDEATQRDPDLAVIEAGSRTLRTHSGQPQGEAVPARPAD
PETDKALRAVEQELAGRWGETKLEPSVTRIAALMDVLGEPQRAYPSIHITGTNGKTSTAR
MIEALLNAFELRTGRYTSPHVQSITERISLDGAPIAPERFIETYEDVKPYVEMVDAQQPY
RLSFFEVLTGMAYAAFADAPVDVAVVEVGMGGTWDATNVIDSTVAVITPISLDHTDRLGT
TPAEIAGEKAGVIKEGATVILAQQPVDAAQVMLKKAVEVDATVAREGMEFGVTSREIAVG
GQLIGLRGLGGEYEEIFLPLYGAHQAHNAAVALAAVEAFFGIGAEQARSLDIDAIRKAFA
SVLSPGRLEVVRSSPTVVLDAAHNPAGAKAAAEGVSEAFSFSRLIGVVGTSADKDVRGLL
EAFEPIFAEIVVTQNSTPRAMDADELAAIAVEVFGDERVQVEPRLDDALEAAITLAEEED
EYAGAGVLVTGSVITVGEARLLLGRG
NT seq
1521 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgagccccgcccagaccggcacgacgagcccgatcccgacgagaccttcgagggg
atcgtcgacgaggcgacccagcgcgaccccgacctggcggtgatcgaggccgggagccgc
acgctgcgcacccactcgggtcagccgcagggcgaagcggtcccggcccgcccggccgac
cccgagaccgacaaggcgctgcgggcggtggagcaggagctcgccggacgctggggcgag
accaagctggagccttccgtcacgcgcatcgccgcgctgatggacgtcctcggcgagccg
cagcgcgcctacccatcgatccacatcaccggcaccaacggcaagaccagcacggcccgc
atgatcgaggccctgctcaacgccttcgagctgcgcaccggccgctacacctccccccac
gtccagtcgatcaccgagcggatcagcctcgacggcgcgccgatcgcacccgagcggttc
atcgagacgtacgaggacgtcaagccgtacgtcgagatggtcgacgcccagcagccctac
cggctctccttcttcgaggtcctcaccgggatggcgtacgcggccttcgccgacgcgccc
gtcgacgtcgcggtcgtcgaggtcggcatgggcggcacctgggacgccaccaacgtgatc
gactccacggtcgctgtcatcaccccgatctcgctggaccacacggaccggctcggcacc
acgcccgccgagatcgcgggggagaaggccggcgtcatcaaggagggcgccacggtcatc
ctggcgcagcagccggtggacgccgcgcaggtgatgctgaagaaggccgtcgaggtggac
gccaccgtggcgcgcgagggcatggagttcggcgtgacctcccgggagatcgcggtcggc
ggccagctgatcggcctgcgcggcctgggcggcgagtacgaggagatcttcctcccgctg
tacggggcccaccaggcgcacaacgcggccgtcgcgctcgccgccgtcgaggcgttcttc
ggcatcggcgcggaacaggcccgctccctcgacatcgacgccatccgcaaggcgttcgcc
tcggtgctctcgccgggccgcctggaggtcgtgcgctccagcccgaccgtcgtcctggac
gccgcgcacaacccggccggggccaaggcggcggcggagggcgtctccgaggcgttcagc
ttctcccggctgatcggcgtggtcggcacgagcgccgacaaggacgtccggggcctcctg
gaggcgttcgagccgatcttcgccgagatcgtcgtcacgcagaactccaccccgcgcgcg
atggacgccgacgagctggccgcgatcgccgtcgaggtcttcggcgacgagcgggtccag
gtcgagccgcgcctcgacgacgcgctggaggcggcgatcacgctggccgaggaggaggac
gagtacgcgggcgccggggtgctggtgaccgggtccgtgatcacggtcggggaagcccgg
ctgctgctcggaaggggctga
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