KEGG   PATHWAY: sce00330
Entry
sce00330                    Pathway                                
Name
Arginine and proline metabolism - Saccharomyces cerevisiae (budding yeast)
Class
Metabolism; Amino acid metabolism
Pathway map
sce00330  Arginine and proline metabolism
sce00330

Module
sce_M00015  Proline biosynthesis, glutamate => proline [PATH:sce00330]
sce_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:sce00330]
sce_M00970  Proline degradation, proline => glutamate [PATH:sce00330]
sce_M00972  Proline metabolism [PATH:sce00330]
Other DBs
GO: 0006525 0006560
Organism
Saccharomyces cerevisiae (budding yeast) [GN:sce]
Gene
YPR062W  FCY1; cytosine deaminase [KO:K03365] [EC:3.5.4.1 3.5.4.21]
YKL184W  SPE1; ornithine decarboxylase SPE1 [KO:K01581] [EC:4.1.1.17]
YPR069C  SPE3; spermidine synthase [KO:K00797] [EC:2.5.1.16]
YLR146C  SPE4; spermine synthase [KO:K00802] [EC:2.5.1.22]
YOL052C  SPE2; adenosylmethionine decarboxylase SPE2 [KO:K01611] [EC:4.1.1.50]
YMR020W  FMS1; polyamine oxidase [KO:K13367] [EC:1.5.3.17]
YOR374W  ALD4; aldehyde dehydrogenase (NADP(+)) ALD4 [KO:K00128] [EC:1.2.1.3]
YPL061W  ALD6; aldehyde dehydrogenase (NADP(+)) ALD6 [KO:K00128] [EC:1.2.1.3]
YER073W  ALD5; aldehyde dehydrogenase (NAD(P)(+)) ALD5 [KO:K00128] [EC:1.2.1.3]
YMR110C  HFD1; hexadecenal dehydrogenase [KO:K00128] [EC:1.2.1.3]
YMR169C  ALD3; aldehyde dehydrogenase (NAD(+)) ALD3 [KO:K00128] [EC:1.2.1.3]
YMR170C  ALD2; aldehyde dehydrogenase (NAD(+)) ALD2 [KO:K00128] [EC:1.2.1.3]
YDR242W  AMD2; putative amidase [KO:K01426] [EC:3.5.1.4]
YPL111W  CAR1; arginase [KO:K01476] [EC:3.5.3.1]
YLR438W  CAR2; ornithine-oxo-acid transaminase [KO:K00819] [EC:2.6.1.13]
YER023W  PRO3; pyrroline-5-carboxylate reductase [KO:K00286] [EC:1.5.1.2]
YLR142W  PUT1; proline dehydrogenase [KO:K00318] [EC:1.5.5.2]
YHR037W  PUT2; 1-pyrroline-5-carboxylate dehydrogenase [KO:K00294] [EC:1.2.1.88]
YDR300C  PRO1; glutamate 5-kinase [KO:K00931] [EC:2.7.2.11]
YHR033W  putative glutamate 5-kinase [KO:K00931] [EC:2.7.2.11]
YOR323C  PRO2; glutamate-5-semialdehyde dehydrogenase [KO:K00147] [EC:1.2.1.41]
YLR027C  AAT2; aspartate transaminase AAT2 [KO:K14454] [EC:2.6.1.1]
YKL106W  AAT1; aspartate transaminase AAT1 [KO:K14455] [EC:2.6.1.1]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
sce00020  Citrate cycle (TCA cycle)
sce00220  Arginine biosynthesis
sce00250  Alanine, aspartate and glutamate metabolism
sce00260  Glycine, serine and threonine metabolism
sce00270  Cysteine and methionine metabolism
sce00310  Lysine degradation
sce00410  beta-Alanine metabolism
sce00470  D-Amino acid metabolism
sce00480  Glutathione metabolism
sce00630  Glyoxylate and dicarboxylate metabolism
sce00650  Butanoate metabolism
sce00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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