Saccharomyces cerevisiae (budding yeast): YJL034W
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Entry
YJL034W CDS
T00005
Symbol
KAR2, GRP78
Name
(RefSeq) Hsp70 family ATPase KAR2
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
5.6.1.10
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce03060
Protein export
sce04141
Protein processing in endoplasmic reticulum
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
YJL034W (KAR2)
04141 Protein processing in endoplasmic reticulum
YJL034W (KAR2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
sce03110
]
YJL034W (KAR2)
04131 Membrane trafficking [BR:
sce04131
]
YJL034W (KAR2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
sce04147
]
YJL034W (KAR2)
Enzymes [BR:
sce01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.10 non-chaperonin molecular chaperone ATPase
YJL034W (KAR2)
Chaperones and folding catalysts [BR:
sce03110
]
Heat shock proteins
HSP70 / DNAK
YJL034W (KAR2)
Membrane trafficking [BR:
sce04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
YJL034W (KAR2)
Autophagy
ER-phagy
ER stress-related proteins
YJL034W (KAR2)
Exosome [BR:
sce04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
YJL034W (KAR2)
Exosomal proteins of other body fluids (saliva and urine)
YJL034W (KAR2)
Exosomal proteins of colorectal cancer cells
YJL034W (KAR2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
BcrAD_BadFG
SPP1_GP23-1
FGGY_C
Radial_spoke_3
Motif
Other DBs
NCBI-GeneID:
853418
NCBI-ProteinID:
NP_012500
SGD:
S000003571
UniProt:
P16474
Structure
PDB
PDBj
LinkDB
All DBs
Position
X:381327..383375
Genome browser
AA seq
682 aa
AA seq
DB search
MFFNRLSAGKLLVPLSVVLYALFVVILPLQNSFHSSNVLVRGADDVENYGTVIGIDLGTT
YSCVAVMKNGKTEILANEQGNRITPSYVAFTDDERLIGDAAKNQVAANPQNTIFDIKRLI
GLKYNDRSVQKDIKHLPFNVVNKDGKPAVEVSVKGEKKVFTPEEISGMILGKMKQIAEDY
LGTKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVLRIVNEPTAAAIAYGLDKSDKEHQI
IVYDLGGGTFDVSLLSIENGVFEVQATSGDTHLGGEDFDYKIVRQLIKAFKKKHGIDVSD
NNKALAKLKREAEKAKRALSSQMSTRIEIDSFVDGIDLSETLTRAKFEELNLDLFKKTLK
PVEKVLQDSGLEKKDVDDIVLVGGSTRIPKVQQLLESYFDGKKASKGINPDEAVAYGAAV
QAGVLSGEEGVEDIVLLDVNALTLGIETTGGVMTPLIKRNTAIPTKKSQIFSTAVDNQPT
VMIKVYEGERAMSKDNNLLGKFELTGIPPAPRGVPQIEVTFALDANGILKVSATDKGTGK
SESITITNDKGRLTQEEIDRMVEEAEKFASEDASIKAKVESRNKLENYAHSLKNQVNGDL
GEKLEEEDKETLLDAANDVLEWLDDNFETAIAEDFDEKFESLSKVAYPITSKLYGGADGS
GAADYDDEDEDDDGDYFEHDEL
NT seq
2049 nt
NT seq
+upstream
nt +downstream
nt
atgtttttcaacagactaagcgctggcaagctgctggtaccactctccgtggtcctgtac
gcccttttcgtggtaatattacctttacagaattctttccactcctccaatgttttagtt
agaggtgccgatgatgtagaaaactacggaactgttatcggtattgacttaggtactact
tattcctgtgttgctgtgatgaaaaatggtaagactgaaattcttgctaatgagcaaggt
aacagaatcaccccatcttacgtggcattcaccgatgatgaaagattgattggtgatgct
gcaaagaaccaagttgctgccaatcctcaaaacaccatcttcgacattaagagattgatc
ggtttgaaatataacgacagatctgttcagaaggatatcaagcacttgccatttaatgtg
gttaataaagatgggaagcccgctgtagaagtaagtgtcaaaggagaaaagaaggttttt
actccagaagaaatttctggtatgatcttgggtaagatgaaacaaattgccgaagattat
ttaggcactaaggttacccatgctgtcgttactgttcctgcttatttcaatgacgcgcaa
agacaagccaccaaggatgctggtaccatcgctggtttgaacgttttgagaattgttaat
gaaccaaccgcagccgccattgcctacggtttggataaatctgataaggaacatcaaatt
attgtttatgatttgggtggtggtactttcgatgtctctctattgtctattgaaaacggt
gttttcgaagtccaagccacttctggtgatactcatttaggtggtgaagattttgactat
aagatcgttcgtcaattgataaaagctttcaagaagaagcatggtattgatgtgtctgac
aacaacaaggccctagctaaattgaagagagaagctgaaaaggctaaacgtgccttgtcc
agccaaatgtccacccgtattgaaattgactccttcgttgatggtatcgacttaagtgaa
accttgaccagagctaagtttgaggaattaaacctagatctattcaagaagaccttgaag
cctgtcgagaaggttttgcaagattctggtttggaaaagaaggatgttgatgatatcgtt
ttggttggtggttctactagaattccaaaggtccaacaattgttagaatcatactttgat
ggtaagaaggcctccaagggtattaacccagatgaagctgttgcatacggtgcagccgtt
caagctggtgtcttatccggtgaagaaggtgtcgaagatattgttttattggatgtcaac
gctttgactcttggtattgaaaccactggtggtgtcatgactccattaattaagagaaat
actgctattcctacaaagaaatcccaaattttctctactgccgttgacaaccaaccaacc
gttatgatcaaggtatacgagggtgaaagagccatgtctaaggacaacaatctattaggt
aagtttgaattaaccggcattccaccagcaccaagaggtgtacctcaaattgaagtcaca
tttgcacttgacgctaatggtattctgaaggtgtctgccacagataagggaactggtaaa
tccgaatctatcaccatcactaacgataaaggtagattaacccaagaagagattgataga
atggttgaagaggctgaaaaattcgcttctgaagacgcttctatcaaggccaaggttgaa
tctagaaacaaattagaaaactacgctcactctttgaaaaaccaagttaatggtgaccta
ggtgaaaaattggaagaagaagacaaggaaaccttattagatgctgctaacgatgtttta
gaatggttagatgataactttgaaaccgccattgctgaagactttgatgaaaagttcgaa
tctttgtccaaggtcgcttatccaattacttctaagttgtacggaggtgctgatggttct
ggtgccgctgattatgacgacgaagatgaagatgacgatggtgattatttcgaacacgac
gaattgtag
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