Saccharomyces cerevisiae (budding yeast): YJL101C
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Entry
YJL101C CDS
T00005
Symbol
GSH1
Name
(RefSeq) glutamate--cysteine ligase
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce00270
Cysteine and methionine metabolism
sce00480
Glutathione metabolism
sce01100
Metabolic pathways
sce01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
YJL101C (GSH1)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
YJL101C (GSH1)
Enzymes [BR:
sce01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
YJL101C (GSH1)
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Motif
Pfam:
GCS
Motif
Other DBs
NCBI-GeneID:
853344
NCBI-ProteinID:
NP_012434
SGD:
S000003637
UniProt:
P32477
Structure
PDB
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Position
X:complement(234320..236356)
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AA seq
678 aa
AA seq
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MGLLALGTPLQWFESRTYNEHIRDEGIEQLLYIFQAAGKRDNDPLFWGDELEYMVVDFDD
KERNSMLDVCHDKILTELNMEDSSLCEANDVSFHPEYGRYMLEATPASPYLNYVGSYVEV
NMQKRRAIAEYKLSEYARQDSKNNLHVGSRSVPLTLTVFPRMGCPDFINIKDPWNHKNAA
SRSLFLPDEVINRHVRFPNLTASIRTRRGEKVCMNVPMYKDIATPETDDSIYDRDWFLPE
DKEAKLASKPGFIYMDSMGFGMGCSCLQVTFQAPNINKARYLYDALVNFAPIMLAFSAAA
PAFKGWLADQDVRWNVISGAVDDRTPKERGVAPLLPKYNKNGFGGIAKDVQDKVLEIPKS
RYSSVDLFLGGSKFFNRTYNDTNVPINEKVLGRLLENDKAPLDYDLAKHFAHLYIRDPVS
TFEELLNQDNKTSSNHFENIQSTNWQTLRFKPPTQQATPDKKDSPGWRVEFRPFEVQLLD
FENAAYSVLIYLIVDSILTFSDNINAYIHMSKVWENMKIAHHRDAILFEKFHWKKSFRND
TDVETEDYSISEIFHNPENGIFPQFVTPILCQKGFVTKDWKELKHSSKHERLYYYLKLIS
DRASGELPTTAKFFRNFVLQHPDYKHDSKISKSINYDLLSTCDRLTHLDDSKGELTSFLG
AEIAEYVKKNKPSIESKC
NT seq
2037 nt
NT seq
+upstream
nt +downstream
nt
atgggactcttagctttgggcacgcctttgcagtggtttgagtctaggacgtacaatgaa
cacataagggatgaaggtatcgagcagttgttgtatattttccaagctgctggtaaaaga
gacaatgaccctcttttttggggagacgagcttgagtacatggttgtagattttgatgat
aaggagagaaattctatgctcgacgtttgccatgacaagatactcactgagcttaatatg
gaggattcgtccctttgtgaggctaacgatgtgagttttcaccctgagtatggccggtat
atgttagaggcaacaccagcttctccatatttgaattacgtgggtagttacgttgaggtt
aacatgcaaaaaagacgtgccattgcagaatataagctatctgaatatgcgagacaagat
agtaaaaataacttgcatgtgggctccaggtctgtccctttgacgctgactgtcttcccg
aggatgggatgccccgactttattaacattaaggatccgtggaatcataaaaatgccgct
tccaggtctctgtttttacccgatgaagtcattaacagacatgtcaggtttcctaacttg
acagcatccatcaggaccaggcgtggtgaaaaagtttgcatgaatgttcccatgtataaa
gatatagctactccagaaacggatgactccatctacgatcgagattggtttttaccagaa
gacaaagaggcgaaactggcttccaaaccgggtttcatttatatggattccatgggtttt
ggcatgggctgttcgtgcttacaagtgacctttcaggcacccaatatcaacaaggcacgt
tacctgtacgatgcattagtgaattttgcacctataatgctagccttctctgccgctgcg
cctgcttttaaaggttggctagccgaccaagatgttcgttggaatgtgatatctggtgcg
gtggacgaccgtactccgaaggaaagaggtgttgcgccattactacccaaatacaacaag
aacggatttggaggcattgccaaagacgtacaagataaagtccttgaaataccaaagtca
agatatagttcggttgatcttttcttgggtgggtcgaaatttttcaataggacttataac
gacacaaatgtacctattaatgaaaaagtattaggacgactactagagaatgataaggcg
ccactggactatgatcttgctaaacattttgcgcatctctacataagagatccagtatct
acattcgaagaactgttgaatcaggacaacaaaacgtcttcaaatcactttgaaaacatc
caaagtacaaattggcagacattacgttttaaaccccccacacaacaagcaaccccggac
aaaaaggattctcctggttggagagtggaattcagaccatttgaagtgcaactattagat
tttgagaacgctgcgtattccgtgctcatatacttgattgtcgatagcattttgaccttt
tccgataatattaacgcatatattcatatgtccaaagtatgggaaaatatgaagatagcc
catcacagagatgctatcctatttgaaaaatttcattggaaaaaatcatttcgcaacgac
accgatgtggaaactgaagattattctataagcgagattttccataatccagagaatggt
atatttcctcaatttgttacgccaatcctatgccaaaaagggtttgtaaccaaagattgg
aaagaattaaagcattcttccaaacacgagagactatactattatttaaagctaatttct
gatagagcaagcggtgaattgccaacaacagcaaaattctttagaaattttgtactacaa
catccagattacaaacatgattcaaaaatttcaaagtcgatcaattatgatttgctttct
acgtgtgatagacttacccatttagacgattcaaaaggtgaattgacatcctttttagga
gctgaaattgcagaatatgtaaaaaaaaataagccttcaatagaaagcaaatgttaa
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