Saccharomyces cerevisiae (budding yeast): YLR420W
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Entry
YLR420W CDS
T00005
Symbol
URA4
Name
(RefSeq) dihydroorotase
KO
K01465
dihydroorotase [EC:
3.5.2.3
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce00240
Pyrimidine metabolism
sce01100
Metabolic pathways
sce01240
Biosynthesis of cofactors
Module
sce_M00051
De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
YLR420W (URA4)
Enzymes [BR:
sce01000
]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.2 In cyclic amides
3.5.2.3 dihydroorotase
YLR420W (URA4)
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Gene cluster
GFIT
Motif
Pfam:
Amidohydro_2
Motif
Other DBs
NCBI-GeneID:
851139
NCBI-ProteinID:
NP_013524
SGD:
S000004412
UniProt:
P20051
Structure
PDB
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Position
XII:963785..964879
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AA seq
364 aa
AA seq
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MVQEIDLGLTCDMHVHVREGAMCELVTPKIRDGGVSIAYIMPNLQPPITTLDRVIEYKKT
LQKLAPKTTFLMSFYLSKDLTPDLIHEAAQQHAIRGVKCYPAGVTTNSAAGVDPNDFSAF
YPIFKAMQEENLVLNLHGEKPSVHDGDKEPIHVLNAEEAFLPALKKLHNDFPNLKIILEH
CTSESAIKTIEDINKNVKKATDVKVAATLTAHHLFLTIDDWAGNPVNFCKPVAKLPNDKK
ALVKAAVSGKPYFFFGSDSAPHPVQNKANYEGVCAGVYSQSFAIPYIAQVFEEQNALENL
KGFVSDFGISFYEVKDSEVASSDKAILFKKEQVIPQVISDGKDISIIPFKAGDKLSWSVR
WEPR
NT seq
1095 nt
NT seq
+upstream
nt +downstream
nt
atggtacaagaaatcgatttaggtttgacatgtgatatgcatgttcatgtaagagagggt
gcgatgtgtgaactagtcacccccaagattagagatggtggggtttcaattgcttacatc
atgccaaatttacaacctccaattaccacactagatagagtgattgaatacaaaaagaca
ctgcagaaactagctcctaaaactaccttcttaatgagtttttatctttcaaaagactta
actccagatttaattcatgaagctgcccaacaacatgccattcgtggagtaaagtgttat
ccagcgggagtaacaacaaattcggctgctggggtggatccaaatgacttcagcgcattt
tacccaattttcaaggctatgcaagaagagaacctggtattaaatttgcatggggaaaaa
ccttctgtccatgatggagacaaagaacctattcatgtattgaatgcagaggaagccttt
ttgccagccttgaaaaaattgcataatgatttcccaaacctgaaaataattctggaacac
tgcactagcgagtcggcaataaagacaatcgaggatataaataagaacgtgaagaaagcc
actgacgtaaaggttgctgccacattaacggctcatcacttatttttaacaattgatgat
tgggccggaaatccggtaaatttttgcaaacctgttgcgaaacttccaaatgacaaaaag
gctctagtcaaagctgctgtatcagggaaaccatattttttctttggatctgattcagca
cctcatcctgtacaaaataaggccaattacgagggtgtttgcgcaggagtttactcacaa
tcttttgcgatcccttatatcgcccaagtttttgaagagcaaaatgccttggagaactta
aagggctttgtttccgacttcggaatttccttttatgaggttaaagatagcgaagtggct
tcttcagataaggcaatattattcaaaaaagaacaagttatccctcaggttatcagcgat
ggcaaagacataagcatcatcccatttaaagcaggtgataaactaagttggtcggtgaga
tgggaacctcgttaa
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