Saccharomyces cerevisiae (budding yeast): YOR108W
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Entry
YOR108W CDS
T00005
Symbol
LEU9
Name
(RefSeq) 2-isopropylmalate synthase LEU9
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce00290
Valine, leucine and isoleucine biosynthesis
sce00620
Pyruvate metabolism
sce01100
Metabolic pathways
sce01110
Biosynthesis of secondary metabolites
sce01210
2-Oxocarboxylic acid metabolism
sce01230
Biosynthesis of amino acids
Module
sce_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
YOR108W (LEU9)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
YOR108W (LEU9)
Enzymes [BR:
sce01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
YOR108W (LEU9)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
CGI-121
Peptidase_M17
GNVR
Motif
Other DBs
NCBI-GeneID:
854275
NCBI-ProteinID:
NP_014751
SGD:
S000005634
UniProt:
Q12166
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Position
XV:523027..524841
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AA seq
604 aa
AA seq
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MVKHSFIALAEHASKLRRSIPPVKLTYKNMLRDPSVKYRAFAPPKMVKRIWPDKTIQKAP
RWLSTDLRDGNQSLPDPMSVAQKKEYFHKLINIGFKEIEVSFPSASQTDFDFTRYAVENA
PDDVGIQCLVQSREHLIKRTVEALTGAKRATIHTYLATSDMFREIVFNMSREEAISKAVE
ATKLVRKLTKDDPSQQATRWSYEFSPECFSDTPGEFAVEICEAVKKAWEPTEENPIIFNL
PATVEVASPNVYADQIEYFSTHITEREKVCISTHCHNDRGCGVAATELGMLAGADRVEGC
LFGNGERTGNVDLVTVAMNMYTQGVSPNLDFSDLTSISEIVHRCNKIPIPPRAPYGGELV
VSAFSGSHQDAIKKGFAIQNKKQAQGETRWRIPYLPLDPKDIGRDYEAVIRVNSQSGKGG
AAWVIMRSLGLDVPRPMQVDFSNTLQKNADALGRELKSEEITKLFKETYNYNNNEHIYVT
LLNYEVKKLNPERRALVGQVEINDKVVNIEGYGNGPISSLVDALSNLLNVKLSVQNYSEH
SLGSGSATQAASFINLSYIKDINNHATSNMWGVGVSEDTGDASIKAVFATVNNIIHSGDV
LLAE
NT seq
1815 nt
NT seq
+upstream
nt +downstream
nt
atggtaaaacattcgttcatagcgctagctgagcatgctagtaaactaagaaggtctatc
ccacccgtcaaactgacttataaaaatatgctacgggacccatcggtaaaatatagggcg
tttgctccaccaaaaatggtcaagaggatttggcctgacaaaactattcaaaaggctcca
cgttggctgtctactgacttgagggacggtaatcaatctttaccggacccaatgtctgtg
gctcaaaagaaagaatatttccacaagttgatcaacatcggtttcaaagaaatcgaagtg
tctttcccctctgcatctcaaacagatttcgacttcaccaggtatgctgtagaaaacgct
ccagatgatgttggtattcaatgtcttgtccaatctagagaacacttgattaaaagaacc
gtggaagcattgactggtgctaaaagggctaccatacatacttacttggccacaagtgac
atgttccgagaaattgtcttcaatatgtctagagaggaagctatttctaaagctgtagaa
gccaccaaactggttaggaaactaaccaaggatgacccttcccagcaagctactcgttgg
tcctatgagttttctcccgaatgtttcagtgatacgccaggtgaatttgctgtagaaatt
tgtgaagctgttaaaaaggcttgggaacctaccgaggaaaatccgatcattttcaactta
ccagctactgtagaagttgcctctccaaatgtttacgctgatcaaattgagtacttctct
acccacattactgagcgtgagaaggtctgtatttctacgcattgtcacaatgaccgtggt
tgcggtgtcgccgccacagaattaggtatgcttgcaggcgctgatcgtgtagaaggttgt
ctatttggtaatggtgaacgtacaggtaatgttgatttggttacagttgccatgaatatg
tatacccaaggtgtttctcctaatttagatttctcagatttaacttcaatttctgaaatt
gtccatcgctgtaacaagattccaattcccccaagagccccatatggcggtgaattggtt
gtttctgccttttctggttctcatcaggatgcaattaagaagggatttgcaatccaaaac
aagaaacaggctcaaggagaaactcggtggagaattccatacttaccattggatccaaag
gatattggacgtgattacgaagccgtcatcagagtcaactctcaatccggtaagggtggt
gctgcttgggttattatgagatctctaggattagatgtaccaagaccaatgcaagttgat
ttctccaatactctacagaaaaatgcagatgccttaggaagagagttaaaatccgaagag
attacaaaattgttcaaagaaacttacaactacaacaacaatgaacatatatacgtcacc
ttgttgaattacgaagttaagaaattgaacccagagcgtagagctttagtgggccaggta
gaaatcaacgataaggttgtcaacatcgaaggctacggaaatggtcctatctcttctttg
gtggatgcgctatccaatttactgaatgttaagttgagcgttcaaaactactctgaacat
tccttgggttctggttctgcaacccaagcggcatctttcataaatctttcctacataaag
gacatcaataatcatgctactagtaatatgtggggtgttggtgtctccgaagacactggg
gatgcatctattaaggcggtatttgctactgtcaataatattattcattccggggatgtt
ctactggcagagtaa
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