Streptococcus parasanguinis FW213: Spaf_2025
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Entry
Spaf_2025 CDS
T02115
Name
(GenBank) dihydrofolate:folylpolyglutamate synthetase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
scf
Streptococcus parasanguinis FW213
Pathway
scf00790
Folate biosynthesis
scf01100
Metabolic pathways
scf01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
scf00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
Spaf_2025
Enzymes [BR:
scf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
Spaf_2025
6.3.2.17 tetrahydrofolate synthase
Spaf_2025
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Ski2_beta-barrel
Motif
Other DBs
NCBI-ProteinID:
AFJ26962
UniProt:
I1ZPI8
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Position
complement(2086463..2087695)
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AA seq
410 aa
AA seq
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MNKIEQWMNSRIGLNFRSGLDRMEQAVSLLGRPDKAYPILHVTGTNGKGSTIAFLRQLLM
AHEKKVGTFTSPHMISIHDRICIGDQPISDEDFTRIGQEVQQMEQTLLQTQDQLSYFEII
CLMALLYFKEQGVDVVLLEIGIGGLLDTTNVVTGEIAVITSIGLDHQETLGGTVAAIAQQ
KAGIFKKGKKAVVGPLSDEAAAVCQEKAKELAVDLHAFEKDFGLEQDHFWNESVELVLPS
LGLKGDYQRENATVALEAFFLYMEGLDQEVDMDQVKLALQETRWPGRLELFGDQSYLDGA
HNPHAMLRLIEFANSLAGKRVKILFGALKRKDYSGMLETLQTGLPEAELILTTFHYGEVV
AQGDRQDLPYVADYKAYIKEFMDQSRPDEVLFVTGSLYFIAEVRAFLLEG
NT seq
1233 nt
NT seq
+upstream
nt +downstream
nt
gtgaataagattgagcaatggatgaatagtcggatcggtctgaattttcgatcgggactg
gatcgtatggagcaggcagtgagccttttagggaggccggataaggcttatccgattctt
catgtgacaggaaccaatgggaagggatccacaatcgcctttctgcgtcaattgttgatg
gctcacgaaaagaaagttgggacctttacctctcctcatatgatcagtatccatgatcgg
atttgtattggggatcagccgatttcagatgaagattttactcggattggtcaagaagtc
caacaaatggagcagaccttgcttcaaacccaggaccaactctcctattttgagattatc
tgtctcatggcccttttgtattttaaggaacaaggagtggatgtggtcctgttggaaatc
ggtatcggtggacttctagataccaccaatgtagtgacaggagagatcgcagtgatcact
tcgattggccttgatcatcaggaaacgctgggagggactgttgccgcaattgctcagcaa
aaggcaggaatctttaagaagggcaagaaagctgtagtgggacccttatccgatgaagct
gcagctgtttgtcaagaaaaagcgaaggaattagctgtggatctccacgccttcgagaaa
gattttggcttagagcaggatcatttttggaatgaaagcgtggaacttgtcttgccgtct
ctgggcttgaagggtgattaccaacgggaaaatgctacagtggctttggaggcctttttc
ctctacatggagggtctagatcaagaagtggatatggatcaggtcaaactggccttacaa
gagacgcggtggccgggacgtctagagttgtttggcgaccagtcgtatttggatggcgcc
cataatcctcacgccatgctgcgcttgatcgagtttgccaatagcttagcaggaaaacgc
gtgaagattttatttggagcccttaagcgaaaagattatagcgggatgctcgaaacgctt
caaacaggtttgccagaagctgaattgattttgacgaccttccattacggagaagtggtg
gcacaaggagaccgacaagacctgccctatgtagctgactacaaggcctatatcaaagag
tttatggatcagagtcgtccagatgaagtcttatttgtcacaggatccttgtattttatt
gcggaagtaagggcatttttattagaggggtaa
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