Streptomyces cinereoruber: CP977_11685
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Entry
CP977_11685 CDS
T07115
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
scin
Streptomyces cinereoruber
Pathway
scin00790
Folate biosynthesis
scin01100
Metabolic pathways
scin01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
scin00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
CP977_11685
Enzymes [BR:
scin01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
CP977_11685
6.3.2.17 tetrahydrofolate synthase
CP977_11685
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QEV32757
UniProt:
A0A5J6IWA6
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All DBs
Position
complement(2630849..2632378)
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AA seq
509 aa
AA seq
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MSEPRDPSDTPDDPTGAPDAFDEIVDNETHRDPDLAVIEAGSRTLRTQAGPPQGDPVPSR
PEDPELDKALREVETELSTRWGETKLEPSVTRIAALMDVLGEPQRAYPTIHITGTNGKTS
TARMIEALLGAFELRTGRYTSPHVQTITERISLDGAPISAERFIETYRDIAPYVDLVDAR
EEYRLSFFEVLTGMAYAAFADAPVDVAVIEVGMGGTWDATNVIDASVAVVTPIDLDHTDR
LGETPAEIAAEKSGIIKPGATVILAQQPVDAAQVLLKKAVEADATVAREGMEFGVASREV
AVGGQLLTLRGLGGEYEDVFLPLHGAYQAHNAAVALAAVEAFFGIGAQHARTLDVDTVRQ
AFARVASPGRLEIVRSSPTVVLDAAHNPHGARATAEGISEAFGFSRLVGVVATSADKDAK
GVLEAFEPILAEVVVTTNSNPRSTDVDALAALAVEVFGEDRVVVEPRLPDAIEAAITLAE
EEAEYGGAGVLVTGSIFTVGDARLLLKRG
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgagccccgcgacccgtccgacacgcccgacgacccgaccggcgcccccgacgcc
ttcgacgagatcgtcgacaacgagacccaccgcgatcccgacctggcggtgatcgaggcc
ggcagccgcaccctgcgcacccaggccggaccgccccagggcgaccccgtgccgagccgc
cccgaggacccggagctcgacaaggcgctgcgcgaggtcgagaccgagctgtccacccgc
tggggcgagaccaagctggagccctcggtcacccgcatcgccgccctgatggacgtcctc
ggcgagccgcagcgcgcgtacccgaccatccacatcaccggcaccaacggcaagacgtcg
acggcccgcatgatcgaggccctgctcggcgccttcgagctgcgcaccggccggtacacc
tcgccgcacgtgcagaccatcaccgagcgcatcagcctcgacggcgccccgatctccgcc
gagcggttcatcgagacgtaccgggacatcgcgccgtacgtggaccttgtcgacgcccgc
gaggagtaccgcctctccttcttcgaggtcctcaccggcatggcgtacgcggccttcgcc
gacgccccggtcgacgtggccgtgatcgaggtcggcatgggcggcacctgggacgccacc
aacgtcatcgacgcctccgtcgccgtcgtcacccccatcgacctcgaccacaccgaccgg
ctcggggagacccccgccgagatcgcggccgagaagtccgggatcatcaagcccggcgcg
accgtcatcctggcccagcagcccgtcgacgccgcccaggtcctcctgaagaaggccgtc
gaggcggacgccaccgtggcccgcgagggcatggagttcggcgtcgcctcccgcgaggtc
gcggtcggcggccagctcctcaccctgcgcggactcggcggcgagtacgaggacgtcttc
ctgccgctgcacggcgcctaccaggcgcacaacgcggccgtggcgctcgccgccgtcgag
gccttcttcggcatcggcgcgcagcacgcccgcaccctcgacgtggacacggtccgtcag
gcgttcgcgcgggtcgcctcgcccggccgcctggagatcgtccgctcctccccgaccgtc
gtcctggacgccgcgcacaacccgcacggcgcgcgggcgaccgccgagggcatcagcgag
gccttcggcttctcccggctcgtcggcgtggtcgccaccagcgccgacaaggacgccaag
ggggtcctggaggccttcgagccgatcctcgcggaggtcgtggtcaccacgaactccaac
ccccgctccaccgacgtggacgcgctcgccgcgctcgcggtcgaggtcttcggcgaggac
cgggtcgtcgtggagccgcggctgcccgacgccatcgaggcggcgatcaccctcgcggag
gaagaggccgagtacggcggcgcgggtgtcctcgtgaccggttcgatcttcacggtcggc
gacgcccggctgctgctcaagaggggctga
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