Streptomyces cyanogenus: S1361_05090
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Entry
S1361_05090 CDS
T07416
Symbol
eryA2
Name
(GenBank) Erythronolide synthase, modules 3 and 4
KO
K24556
tylactone synthase 3
Organism
scyg
Streptomyces cyanogenus
Pathway
scyg01052
Type I polyketide structures
scyg01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
scyg00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01052 Type I polyketide structures
S1361_05090 (eryA2)
00522 Biosynthesis of 12-, 14- and 16-membered macrolides
S1361_05090 (eryA2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
scyg01008
]
S1361_05090 (eryA2)
Polyketide biosynthesis proteins [BR:
scyg01008
]
Polyketide synthase (PKS)
Modular type I PKS
cis-AT PKS
Tylactone synthase
S1361_05090 (eryA2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Acyl_transf_1
KR
Ketoacyl-synt_C
PKS_DH_N
ADH_zinc_N_2
PS-DH
KAsynt_C_assoc
ADH_zinc_N
PP-binding
adh_short
Docking
ADH_N
Thiolase_N
Epimerase
Polysacc_synt_2
ACP_syn_III
GDP_Man_Dehyd
Motif
Other DBs
NCBI-ProteinID:
QTD96714
LinkDB
All DBs
Position
1164338..1170883
Genome browser
AA seq
2181 aa
AA seq
DB search
MSNEDRLRDYLKRVTAELHQTRRRLDAAETGIAEPIAVVSMACRYPGGVRSPEDLWHLLT
HAGDAIGDFPTRRGWDLDNLFDPDPDTTGTSYARQGGFLHDADHFDAEFFGISPREALTI
DPQQRLLLETAWETLERAGLDPTRLRGSRTGVFTGVMYSDYGARLVHDAPGEVEAYLGTG
SAHSVASGRVSYTFGLEGPAVSVDTACSSSLVAMHLAAQALRTGECELALAGGVTVMATP
TTFVEFSRQRGLAADSRVKAFAAAADGTALAEGSALVLLERLSDAQRNGHPVLAVIRGSA
VNQDGASSQLSAPNGPSQQRVIHQALTNAGLTPDLIDAVEAHGTGTTLGDPIEAQALLAT
YGQNRTTDQPLWLGSVKSNIGHTQAAAGIAGVIKMVQAIHHGVLPKTLHINEPTPHVDWE
SGAVKLLTEQTPWPDTGHPRRAAVSSFGISGTNAHLILEAAPPSTTTNQHTEQPPADTPL
PYLLSAKTQTALRTQATRLHHHLTHHPHLDTTAVARTLATTRTHFDHRAAVIATDTTDLL
NGLTTLANGETAPHTLQGRTTEGGVVFVFPGQGSQWPGMASELLASSAPFREKAEECDAA
LREFLDWSVLDVLSGEPGAPSFDRVDVVQPVLFTMMVSLAAVWRAGGVEPSAVVGHSQGE
IAAAYVAGGLSLEDAARVVALRSRAWLRLAGRGGMAAVSLGAPELRPRLERWGERLSVAA
VNSPGTAAVAGEPEALRELVAELHGEGVQARLIPGIDTAGHSAQVDVFHDHLSEVLAPVA
PRSSSVPFYSTVTGALLDTSGLDAAYWYRNMREPVDFEAATRALLADGHRVFLETSPHPM
LAASLQETAGDADADVAVLHTLRRDHGDRTRIITALADAHLQGVAVDWPAVLGAGRTVPL
PTYGFQYQPHWLDAPITADAAATGLTPTDHPLLSALVELPDGQGYVFTGRLSLQTHPWLA
GHAVLEQVLLPGTAFVDVLLHAGAHSGCGRIGELTLQAPLVLPDRGAVHLRVTVGATEDD
GRQSCTVHSRPADAEPGTPWLVHATAVLEPEGAPDAFDFGTWPPADATALDHTDLYDRLA
GIGLAYGAPFRGLRGAWWDGTAVYADVVLEEPGDPAGYGVHPALLDAALHSIGLDTADGG
TGGYVAAGVQLPFAWNDVRLYATGASRLRVRLTRTGDDTVALDVADTSGTPVAAIGSLTM
RPLSTDLLSAARPDRHDALFQLDWTAVPVPARAAADGPIAVVGDGLPTAADAVGSVPVYA
DLTALVRAVDEGAPVPESVLVLAPGRTDEDPAHRTRVALDAVLGLLQGWLADDRFAGSRL
AVLTDRAVAVTDQEADRDLSQAAIWGLVRTAQSENPDRIVLVDLDGTDRSTALVTAALAT
GEPQLAVREGVFHAPRLARAGASRALELPGDRTWRIDVAEPGTLESLAAVDNPAAQRPLA
DGEVRISVRAAGLNFRDALVALGMVPGQEIMGSEAAGVVVETGPGVSGIAVGDRVMGLFT
GALGPLAVTDHRLVMPVPAGWSNSQAASTPVVFLTAYYGLKHLANLRPGQRVLIHTATGG
VGMAAVQLARHLGAEIFTTASLPKQHLLRADGFAEDHIADSRTLDFADEFLAATGGEGVD
VVLNSLAHEFVDASLRLLPRGGHFLEMGKTDRRDPSEVAAAHPGVRYRTFNLDSDGPEHV
QEMLAELAGLFARGALRPLPYTAWDVRTAPDALRYLGQARHTGKLVLTLPRALDPDGTAL
VVGGTGTLGSLTARHLVTEHGIRRMLLTSRQGENAETAGELRADLAALGAEVTIAACDAA
DPEALAALLTSVPDAHPLTVVVHAAAVLDDAVLPALTPERVDTVLRPKIDAAWNLHQLTK
DLDIAAFVLFSSAAGVLGNAGQAGYAAANTFLDALAQHRRSLGLPATSLAWGLWEQTSQL
TAQLQHADRARLARASITAMPTAQALSLLDAALGSYRAVAVPVRFDLGVLRSLAAAGTLP
PILRGLVRSPGRRAIGSGPAQDTPAEDWAQRLSGITPDRQLDLLVQLVRTNAAVVLGHSD
HSSIDESRAFKELGFDSLTAVELRNRLGKAVGLRLPSTVVFDNPTPTALAARLHSELAPR
GAAAHQVVLDGLERLEKLALAAAADQDVRDEISGRVRDFLFRLDQMDVPGARSGAAPEAD
VAGLIDSASDDEIFAFIENEL
NT seq
6546 nt
NT seq
+upstream
nt +downstream
nt
atgtcgaatgaggaccggctgcgcgactacctcaagcgtgtgaccgcggaactgcaccag
acgcgccggcggctggacgcggccgagacggggatcgccgagccgatcgccgtggtgtcg
atggcctgccgctaccccggcggcgtccgctcccccgaggacctgtggcacctgctcacc
cacgccggcgacgccatcggcgacttccccacccgacgcggctgggacctcgacaacctc
ttcgaccccgaccccgacaccaccggcacgagctacgcccgccaaggcggcttcctccac
gacgccgaccacttcgacgccgagttcttcggcatcagcccccgcgaagccctcaccatc
gacccccagcagcgcctcctgctcgaaaccgcctgggaaaccctcgaacgcgccggcctg
gaccccacccggctccgcggcagccgcaccggcgtcttcaccggcgtcatgtacagcgac
tacggcgcacgcctcgtccacgacgctccgggggaggtcgaggcctacttgggcacgggc
agcgcccacagtgtcgcgtcgggacgggtgtcgtacaccttcggcctcgaaggccccgcc
gtcagcgtggacaccgcgtgctcgtcctcgctcgtcgcgatgcacctggcggcgcaggca
ctgcgcaccggcgagtgcgaactcgccctcgccggcggagtcaccgtcatggccacgccc
accactttcgtggagttcagccggcagcgcgggctcgccgcggacagccgggtcaaggcg
ttcgcggcggccgccgacggcacggccctggccgagggttccgcgctggtgctgctggag
cggctgtcggacgcccagcgcaacggtcaccccgtgctcgccgtcatccgcggctcggcc
gtcaaccaggacggcgccagcagccagctcagcgcccccaacggcccctcccagcaacgc
gtcatccaccaggccctgaccaacgcaggcctcacacccgacctgatcgacgcggtggaa
gcacacggcaccggcaccaccctcggcgaccccatcgaagcccaggccctcctcgccacc
tacggccagaaccggaccaccgaccaacccctctggctcggctccgtcaaatccaacatc
ggccacacccaagccgccgcaggcatcgccggcgtcatcaaaatggtccaagccatccac
cacggcgtgctgcccaagaccctccacatcaacgaacccacaccccacgtcgactgggaa
tcaggcgcggtcaaactgctcaccgagcaaaccccctggcccgacaccggccacccccgc
cgcgccgccgtctcctccttcggcatcagcggcaccaacgcccacctcatcctcgaagca
gcacccccatccaccaccaccaaccagcacaccgaacaaccccccgcagacacccccctg
ccctacctcctgtccgcaaagacccaaaccgccctgcgcacccaagccacccgcctgcac
caccacctcacccaccacccccacctcgacaccaccgccgtcgcccggacactcgccacc
acccgcacccacttcgaccaccgcgccgccgtcatcgccaccgacaccaccgacctgctc
aacggcctcaccacactggccaacggcgaaacagccccccacaccctgcaaggacggacg
acggagggcggagtcgtcttcgtcttccccggccagggctcccagtggcccggaatggcg
agcgaactcctcgcctcctcggccccgttccgggagaaggccgaggagtgcgacgccgcg
ctgagggagttcctggactggtcggtactggacgtgctgagcggtgagcccggcgcgccg
tcgttcgaccgggtcgacgtggtgcagccggttctgttcacgatgatggtgtcgctcgcc
gccgtgtggcgggcgggcggcgtcgagccgtccgcggtggtcgggcactcccagggtgag
atcgccgccgcgtacgtcgcgggcggtctgtcgctggaggacgccgcccgcgtcgtggcg
ctgcgcagtcgggcctggctgcggctggccgggcgcggcggcatggcggccgtctcgctc
ggcgcgccggagctgcgaccccgcctggagcgctggggcgaacggctctcggtcgccgcc
gtgaacagcccggggacggccgcggtggccggtgagccggaggccttgcgggaactggtc
gcggagctccacggggagggcgtacaggcgcgcttgatccccggtatcgacaccgccggg
cactccgcgcaggtggacgtcttccacgaccacctctccgaggtactggccccggtggct
ccgcgctcctcgtcggtgccgttctactcgacggtgaccggcgcactgctcgacaccagc
gggctcgacgccgcctactggtaccgcaacatgcgcgagccggtggacttcgaggcggcg
acccgagcgctgctggccgacgggcaccgggtgttcctggagaccagtccgcatcccatg
ctggccgcgtcgctgcaggagacggcgggggacgcggacgccgacgtcgccgtactgcac
acgctgcgacgcgaccacggcgaccggacgcggatcatcaccgcactcgccgacgcccat
ctgcagggagtcgccgtggactggccggccgtgctgggcgcgggtcggaccgtgccgctg
cccacgtatggcttccagtaccagccgcactggctggacgcgccgatcaccgcggatgcc
gccgccaccggactgacaccgaccgatcacccgctgctgagcgcgctcgtggaactcccc
gacggccaggggtacgtgttcacgggccgtctctccctccagacacatccgtggctggcc
gggcacgccgtcctggaacaggtgctgctgccggggaccgcgttcgtggacgtcctgctg
cacgccggtgctcacagcggctgcggtcggatcggcgaactcactcttcaggcaccgctg
gtgctgcccgatcggggagccgtccaccttcgggtcacggtgggcgccacggaggacgac
ggccggcagagctgcaccgtccactcgcgccccgcggacgccgagccgggaacgccgtgg
ctggtgcacgccacggccgtactcgaaccggagggcgcgcccgacgccttcgacttcggg
acctggccgccggccgacgccaccgcactcgaccacacggacctgtacgaccggctggcc
gggatcggcctggcctacggggccccgttccgggggctgcgcggcgcctggtgggacggg
acggcggtgtacgccgacgtcgtgctggaggagccgggcgacccggccgggtacggcgtc
caccccgcactcctggacgccgcgctgcactcgatcggcctggacaccgccgacggcgga
acgggcggctacgtggccgcaggggtgcagctgccgttcgcctggaacgacgtcaggctg
tacgccaccggcgcgtcccggctccgcgtacggctgacccgcacaggcgacgacacggtg
gccctggatgtggccgacacatcgggcacgccggtcgccgccatcgggtcgctcaccatg
cgtccgctcagcaccgatctgctgtccgccgcgcggcccgaccgtcacgacgcgctgttc
cagctggactggacggccgttccggtcccggcccgagccgccgcggacgggccgatcgcc
gtcgtcggcgacgggctgccgaccgccgccgacgcggtgggttcggtgccggtgtatgcg
gacctgaccgcgctggtgcgggcggtggacgagggtgccccggttccggaaagcgtcctc
gtcctcgcccccggacgtacggacgaggaccctgcccaccgtacccgggtggcgttggac
gccgtgctcggcctgctccagggctggctggcggacgaccgtttcgccggcagccgactg
gccgtcctcaccgaccgggcggtcgccgtgaccgaccaggaggcggaccgtgacctgtcg
caggccgccatctggggcctggtgcgcacggcgcagtcggagaaccccgaccggatcgta
ctggtcgacctcgacggcaccgaccggtccaccgcactggtgaccgcggcactggcgacc
ggtgaaccccaactcgccgtgcgtgaaggggtgttccacgcaccgcggctggcccgcgcc
ggagcctctcgggcgctggagctgcccggggaccgtacgtggcggatcgacgtggccgag
cccggcaccctggagtcgcttgcggcggtcgacaacccggcggcacaacggccgctggcg
gacggagaggtcaggatctccgtacgggcggccggactgaacttccgggacgcgctggtc
gcgctgggcatggtgcccggacaggagatcatgggcagcgaggcggccggcgtggtcgtc
gagaccggtcccggtgtctccggcatcgcggtgggcgatcgggtcatgggtctgttcacc
ggcgcgctcgggccgctcgcggtcaccgaccaccggctggtcatgccggtacccgccggc
tggagcaactcccaggcggcatcgaccccggtggtcttcctcacggcctactacggtctc
aagcacctggcaaacctgcgtcccgggcagcgcgtgctgattcacaccgcgaccggcggc
gtcggaatggccgccgtccaactcgcccggcacctcggtgcggagatcttcaccaccgcc
tcccttcccaagcagcacctgctgcgggccgacgggttcgccgaggaccacatcgccgac
tcccgcacactggacttcgcggacgagttcctggcggccaccggcggcgagggcgtcgac
gtcgttctcaactccctggcccacgagttcgtcgacgcctcgctgcggctgttgccgcgc
gggggccacttcctggaaatgggcaagaccgaccggcgcgacccctccgaagtggccgcc
gctcatcccggggtgcggtacaggacgttcaacctggactccgacggacccgagcacgtc
caggagatgctggccgagctggccggtctcttcgcgcgcggtgcactgcgcccgctgccc
tacaccgcatgggacgtgcgcacggcacccgacgccctgcggtacctgggccaggcacgc
cacaccggcaagctggtactcacccttccgcgcgccctcgaccccgacgggaccgcgctc
gtcgtcggtggcaccggaactctggggagtctgactgcccggcacctggtgaccgaacac
ggcatccgccgcatgctgctgaccagtcgtcagggcgagaatgccgagacagccggggaa
ctgcgggccgacctggccgctctgggcgccgaggtcaccatcgccgcctgcgacgccgcg
gaccccgaggccctggcagcgctgctcacctcggtccccgacgcccatccgctcacggtc
gtagtgcacgccgccgccgtcctcgacgacgccgttctccccgccctgacacccgagcgt
gtagacaccgtcctgcgtccgaagatcgacgccgcctggaacctgcaccagctgacgaag
gacctcgacatcgccgccttcgtcctgttctcctccgccgcgggtgtgctcggcaacgcg
gggcaggcgggctacgccgctgccaacaccttcctcgacgccctggcccagcaccgcagg
tccctcggcctgcccgccacctcgctcgcctggggcctgtgggaacagaccagccagctc
accgcacagctccagcatgccgaccgggcacggctggcccgggccagcatcacggccatg
ccgacggcccaggccctgtccctgctcgacgccgcgctcggctcctaccgtgccgttgcc
gtcccggtccggttcgacctcggggtgctgcgctcgctggccgcggcgggaacgctcccg
ccgatcctgcggggacttgtccgctccccagggcgccgtgcgatcggctccggccccgcg
caggacacgccggccgaggactgggcacagcggctgagcgggatcactcccgaccgacag
ctcgacctcctggtgcagctcgtccgcacgaacgccgccgtggtgctcggccactcggac
cactcgtccatcgacgagtcacgggcgttcaaggagctcggcttcgactcgctgacggcg
gtggaactgcgcaaccggctgggcaaagccgtcggcctgcgcctgccctcgaccgtggtc
ttcgacaacccgacgccgacggcgctcgccgctcgcctgcactcggagctggccccccgg
ggcgcggccgcccaccaggtggtcctggacggcctggagcgcctggagaagctcgcgctc
gccgccgccgcggaccaggacgtacgcgacgagatctccggccgggtgagggacttcctc
ttccggctcgaccagatggacgtccccggtgcccggtccggggccgcgccggaggcggat
gtcgccgggctcatcgactcggccagtgacgacgagatcttcgccttcatcgagaacgag
ctgtaa
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