Streptomyces dangxiongensis: D9753_23635
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Entry
D9753_23635 CDS
T08044
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sdd
Streptomyces dangxiongensis
Pathway
sdd00790
Folate biosynthesis
sdd01100
Metabolic pathways
sdd01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sdd00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
D9753_23635
Enzymes [BR:
sdd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
D9753_23635
6.3.2.17 tetrahydrofolate synthase
D9753_23635
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AYN41375
UniProt:
A0A3G2JJ04
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Position
5250837..5252351
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AA seq
504 aa
AA seq
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MSDHPGTSDTPDPLDAFEELIAEETDRDPDLAVIEAGSRTLRTQGGSPQADVPGRPEDPE
VDKALREVETELATRWGETKLEPSVARIAALMDVLGDPQRAYPSIHITGTNGKTSTARMI
EALLGAFELRTGRYTSPHVQSVTERISLDGAPVSAERFVETYQDIKPYVEMVDSAQEYRL
SFFEVLTGMAYAAFADAPVDVAVVEVGMGGSWDATNVIDGDVAVITPIDLDHTDRLGGTT
AEIAVEKSGIVKQGATVILAQQPVDAAQVLLKKAVEVDATVAREGLEFGIVARQVAVGGQ
MVTLRGLGGEYPEVYLPLHGAHQAHNASVALAAVEAFFGVGAQRAEPLDIDTVRKAFAAV
SSPGRLEVVRRSPTVVLDAAHNPAGAEAAAEAVREAFDFSRLIGVVGASGDKNVRGLLEA
FEPIFAEVVVTQNSSHRAMDADELAAIAVEVFGDERVQVEPRLPDALEAAITLAEEEGEF
SGGGVLVTGSVITVGEARLLLGKG
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgaccaccccggcaccagtgacacccccgaccccctcgacgccttcgaggagctg
atcgcggaagagaccgaccgtgaccccgacctagcggtgatcgaggccggcagccgtacc
ctgcggacccagggcggctccccgcaggccgacgtacccgggcgcccggaggacccggag
gtcgacaaggccctgcgcgaggtcgagacggagctggccacccgctggggcgagaccaag
ctggagccctcggtcgccaggatcgccgcgctgatggacgtgctgggcgatccgcagcgg
gcgtacccctcgatccacatcacgggcaccaacggcaagacctccaccgcccgcatgatc
gaggccctgctcggcgccttcgagctgcgcaccggccgctacaccagcccccacgtgcag
tcggtcaccgagcggatcagcctggacggcgccccggtctccgccgagcggttcgtcgag
acgtaccaggacatcaagccgtacgtggagatggtcgactccgcgcaggagtaccggctg
tccttcttcgaggtcctgaccggcatggcgtacgccgccttcgccgacgcgcccgtcgac
gtcgccgtggtcgaggtcggcatgggcggctcctgggacgcgacgaacgtgatcgacggc
gacgtcgccgtcatcaccccgatcgacctggaccacaccgaccgcctcggcgggacgacc
gcggagatcgccgtcgagaagagcggcatcgtcaagcagggcgcgaccgtcatcctggcc
cagcagccggtggacgcggcgcaggtgctgctgaagaaggccgtcgaggtggacgccacg
gtcgcccgtgaggggctggagttcgggatcgtcgcccgccaggtcgccgtcggcgggcag
atggtcacgctgcgcggcctcggcggcgagtaccccgaggtgtacctcccgctgcacggt
gcccaccaggcgcacaacgcgtccgtcgcgctcgccgccgtcgaggcgttcttcggcgtc
ggtgcgcagcgcgccgaaccgctggacatcgacacggtgcgcaaggcgttcgcggcggtg
tcctcgccgggccgtctggaggtcgtacggcgctccccgacggtcgtgctggacgccgcg
cacaacccggcgggcgccgaggccgccgcggaggcggtgcgcgaggcgttcgacttcagc
cggctgatcggggtcgtcggcgcgagcggcgacaagaacgtgcgggggctgctggaggcc
ttcgagccgatcttcgccgaggtcgtcgtcacgcagaactccagccaccgggccatggac
gcggacgagctggccgcgatcgccgtcgaggtgttcggcgacgagcgggtccaggtcgag
ccgcggctgccggacgccctggaggccgcgatcacgctggccgaggaggagggcgagttc
tcgggcggtggcgtgctggtcaccggttccgtcatcacggtcggcgaggcccggctgctg
ctgggaaagggctga
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