Streptomyces drozdowiczii: NEH16_16220
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Entry
NEH16_16220 CDS
T09042
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
sdrz
Streptomyces drozdowiczii
Pathway
sdrz00280
Valine, leucine and isoleucine degradation
sdrz00640
Propanoate metabolism
sdrz00785
Lipoic acid metabolism
sdrz01100
Metabolic pathways
sdrz01110
Biosynthesis of secondary metabolites
sdrz01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
sdrz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
NEH16_16220 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
NEH16_16220 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
NEH16_16220 (pdhA)
Enzymes [BR:
sdrz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
NEH16_16220 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
UZK55462
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Position
3576857..3578020
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AA seq
387 aa
AA seq
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MTVESTAAARKPRRSSKRTSAAKTPAKTPEGSTPELVQLLTPEGERVEHPDYSIDLSAEE
LRGLYRDMVLTRRFDAEATALQRQGELGLWASLLGQEAAQIGSGRALRDDDYVFPTYREH
GVAWCRGVDPTNLLGMFRGVNHGGWDPNSNNFHLYTIVIGSQTLHATGYAMGVAKDGADS
AVVAYFGDGASSQGDVAEAFTFSAVYNAPVVFFCQNNQWAISEPTEKQMRVPLYQRAQGF
GFPGVRVDGNDVLACLAVTKSALERARRGEGPTLVEAFTYRMGAHTTSDDPTKYRADEER
AAWEAKDPILRLRTYLEKQGAADEAFFTALDEESEALGKRVREAVRAMPDPDRMAMFDHV
YADGNPLVDEERAEFAAYQASFAEEGK
NT seq
1164 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtggagagcactgctgccgcgcgtaaaccgcgacgcagcagcaagcggaccagc
gccgcgaagacgcccgcgaagacgccggagggttcgacgcccgagctggtacagctgctg
acgcccgagggcgagcgggtcgagcacccggactactcgatcgacctgagcgcggaagag
ctgcgcggcctgtaccgggacatggtcctcacccgccgcttcgacgccgaggccaccgca
ctccagcgccagggcgagctgggcctgtgggcctcgctgctcggccaggaggccgcccag
atcggttccggccgggccctgcgcgacgacgactacgtcttcccgacctaccgtgagcac
ggtgtggcctggtgccggggcgtcgacccgaccaatctgctcgggatgttccgcggtgtg
aaccacggcggctgggacccgaacagcaacaacttccacctgtacacgatcgtcatcggc
tcgcagaccctgcacgccaccggctacgccatgggcgtggccaaggacggcgcggactcg
gccgtggtcgcgtacttcggcgacggcgcctccagccagggcgacgtcgcggaggcgttc
accttctccgccgtctacaacgccccggtcgtcttcttctgccagaacaaccagtgggcg
atctccgagcccaccgagaagcagatgcgggtgccgctctaccagcgcgcccagggcttc
ggcttccccggcgtccgcgtcgacggcaacgacgtcctggcctgcctggccgtcaccaag
tccgccctggagcgggcccggcgcggcgagggcccgaccctggtcgaggcgttcacgtac
cgcatgggcgcgcacaccacgtccgacgacccgacgaagtaccgggcggacgaggagcgc
gcggcctgggaggccaaggacccgatcctgcgcctgcgcacgtacctggagaagcagggc
gcggccgacgaggcgttcttcaccgccctggacgaggagagcgaggccctcggcaagcgc
gtccgcgaggccgtacgggcgatgcccgacccggaccggatggcgatgttcgaccacgtc
tacgccgacggcaacccgctcgtcgacgaggagcgcgccgagttcgccgcctaccaggct
tcgttcgccgaggagggcaagtaa
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