Streptomyces drozdowiczii: NEH16_22170
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Entry
NEH16_22170 CDS
T09042
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sdrz
Streptomyces drozdowiczii
Pathway
sdrz00010
Glycolysis / Gluconeogenesis
sdrz00020
Citrate cycle (TCA cycle)
sdrz00620
Pyruvate metabolism
sdrz00785
Lipoic acid metabolism
sdrz01100
Metabolic pathways
sdrz01110
Biosynthesis of secondary metabolites
sdrz01120
Microbial metabolism in diverse environments
sdrz01200
Carbon metabolism
sdrz01210
2-Oxocarboxylic acid metabolism
Module
sdrz_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sdrz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
NEH16_22170 (aceE)
00020 Citrate cycle (TCA cycle)
NEH16_22170 (aceE)
00620 Pyruvate metabolism
NEH16_22170 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
NEH16_22170 (aceE)
Enzymes [BR:
sdrz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
NEH16_22170 (aceE)
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Motif
Pfam:
PDH_E1_M
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
UZK56435
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Position
complement(4882382..4885123)
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AA seq
913 aa
AA seq
DB search
MASGSDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATKDEPFFPGDEEIERKVLNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDDGLGGDQIFFQGHASPGIYARAFLLDRLSEAQLDAFRQ
EKSKAPNGLSSYPHPRLMPDFWEFPTVSMGLGPLGAIYQARMNRYMEARGLADTSNSHVW
AYLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKVIQELESQFRGA
GWNVIKLVWDRSWDPLLAQDRTGILVNKLNTTPDGQFQTYATETGAYIREHFFGDDPRLR
EMVKDMTDQQILHLGRGGHDHRKVYAAYAAAKAHKGQPTVILAQTVKGWTLGPNFEGRNA
THQMKKLTAEDLKRFRDRLHIPIADKELEDGNPPYYHPGRDSEEIQYMHDRRKGLGGYVP
TRVVRAKPLPLPEDKTYAAAKKGSGQQSIATTMAFVRILKDLMRDKEIGKRFVLIAPDEY
RTFGMDAFFPSAKIYNPLGQQYESVDRDLLLAYKESPTGQMLHDGISEAGCTASLVAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPACVAYDPAFGYEIAHIVQDGLRRMYGGTPEENEDVFYYLTVYNEPIQHPA
EPADVDVEGILKGVYRYSSGEKGEIPAQILASGVAVPWAVEAQRILADEWNVKADVWSAT
SWNELRREAVDVERYNLLHPEEEQRVPYVTRKLSGAQGPFVAVSDWMRSVPDQIARWVPG
TYQSLGADGFGFADTRGAARRYFHIDAQSIVLGVLTELAKEGKVDRSALKTAVDRYDLLD
VASADPGAAGGDA
NT seq
2742 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatccgatcgcaacccgatcatcattggcggccttccgagtcaggtcccg
gattttgatcccgaagagacccaggaatggctcgactccctcgacgccgccgtcgacgag
cgaggccgtgagcgggcccgctatctcatgctccggctcatcgagcgagcgcgcgagaag
cgcgtcgccgtgccggagatgcgcagcacggactacgtcaacacgatcgccacgaaggac
gagccgttcttccccggcgacgaggagatcgagcgcaaggtcctcaacgcgacccgctgg
aacgcggccgtgatggtctcgcgcgcccagcgtccggggatcggcgtgggcggtcacatc
gcgacgttcgcctcctcggcctcgttgtacgacgtcggcttcaaccacttcttccgcggc
aaggacgacggtctcggcggcgaccagatcttcttccaggggcacgcctcgccggggatc
tacgcccgcgccttcctgctggaccggctgagcgaggcgcagctcgacgcgttccgccag
gagaagtcgaaggcgccgaacgggctgtccagctatccgcacccgcggctgatgccggac
ttctgggagttcccgacggtgtcgatgggcctcggcccgctcggcgcgatctaccaggcg
cggatgaaccgctacatggaggcgcgcggcctcgccgacacgtcgaactcgcatgtgtgg
gcgtatctcggtgacggcgagatggacgagcccgagtcgctcggccagctgtccatcgcc
gcccgcgagggcctggacaacctgaccttcgtcgtcaactgcaacctccagcgcctcgac
ggcccggtgcgcggcaacggcaaggtcatccaggagctggagtcccagttccggggcgcc
gggtggaacgtgatcaagctggtctgggaccggtcctgggacccgctgctggcgcaggac
cgcacgggcatcctggtcaacaagctgaacacgacgccggacgggcagttccagacgtac
gcgacggagaccggcgcgtacatccgggagcacttcttcggggacgacccgaggctgcgc
gagatggtcaaggacatgaccgaccagcagatcctgcacctggggcgcggcggtcacgac
caccgcaaggtgtacgcggcctatgcggcggccaaggcccacaagggccagccgacggtg
atcctggcgcagacggtcaagggctggaccctcgggccgaacttcgagggccgcaacgcg
acccaccagatgaagaagctcaccgccgaggacctgaagcggttccgggaccggctgcac
atcccgatcgcggacaaggagctggaggacggcaacccgccgtactaccacccgggccgc
gactcggaggagatccagtacatgcacgaccgccgcaagggcctgggcggttacgtcccg
acccgcgtggtgcgcgcgaagcccctgccgctgcccgaggacaagacgtacgcggcggcg
aagaagggctcgggccagcagtcgatcgccaccaccatggcgttcgtccgcatcctgaag
gacctcatgcgggacaaggagatcggcaagcgcttcgtgctgatcgcgcccgacgagtac
cgcacgttcggcatggacgccttcttcccgagcgcgaagatctacaacccgctcgggcag
cagtacgagtcggtggaccgcgatctgctgctcgcgtacaaggagtcgccgaccgggcag
atgctgcacgacggcatctcggaggcgggctgcacggcctcgctggtcgccgcgggctcc
gcctacgcgacgcacggcgagccgctgatcccggtgtacgtcttctactcgatgttcggc
ttccagcgcaccggtgaccagttctggcagatggccgaccagctggcgcgcggcttcgtg
ctgggcgcgacggccggccggacgacgctgaccggcgaggggctccagcacgccgacggg
cactcccagctgctggcgtcgaccaacccggcctgcgtggcctacgacccggcgttcggg
tacgagatcgcgcacatcgtgcaggacggtctgcgccggatgtacggcgggacgcccgag
gagaacgaggacgtcttctactacctgaccgtctacaacgagccgatccagcacccggcg
gagcccgccgacgtcgacgtcgagggcatcctgaagggcgtctaccgctacagcagcggg
gagaagggcgagatcccggcccagatcctggcgtccggtgtggcggtgccgtgggcggtc
gaggcgcagcgcatcctcgcggacgagtggaacgtgaaggcggacgtctggtcggcgacc
tcctggaacgagctgcggcgcgaggctgtggacgtggagcggtacaacctgctccacccg
gaggaggagcagcgcgtgccgtacgtgacgcgcaagctgtccggggcgcaggggccgttc
gtggcggtgtcggactggatgcggtccgtgcccgaccagatcgcccgctgggtgcccggc
acctaccagtcgctgggcgcggacggtttcgggttcgcggacacccggggcgcggcgcgg
cggtacttccacatcgacgcgcagtcgatcgtgctcggggtgctcaccgagctggcgaag
gaggggaaggtcgaccggtcggcgctgaagacggcggtcgaccgctacgacctgctggac
gtggcctcggccgatccgggggccgcgggcggcgacgcgtaa
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