Streptococcus dysgalactiae subsp. equisimilis GGS_124: SDEG_1250
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Entry
SDEG_1250 CDS
T00932
Symbol
acoA
Name
(GenBank) pyruvate dehydrogenase E1 component alpha subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
sds
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Pathway
sds00010
Glycolysis / Gluconeogenesis
sds00020
Citrate cycle (TCA cycle)
sds00620
Pyruvate metabolism
sds00785
Lipoic acid metabolism
sds01100
Metabolic pathways
sds01110
Biosynthesis of secondary metabolites
sds01120
Microbial metabolism in diverse environments
sds01200
Carbon metabolism
sds01210
2-Oxocarboxylic acid metabolism
Module
sds_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sds00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SDEG_1250 (acoA)
00020 Citrate cycle (TCA cycle)
SDEG_1250 (acoA)
00620 Pyruvate metabolism
SDEG_1250 (acoA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SDEG_1250 (acoA)
Enzymes [BR:
sds01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SDEG_1250 (acoA)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
BAH81745
UniProt:
A0A9W4EH25
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Position
1:complement(1198475..1199455)
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AA seq
326 aa
AA seq
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MEAKMVTVSKEQYLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVGEEAANVGAVAHL
TYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKATGVSKGRGGSMHLADFEKGNYGTNGI
VGGGYALAVGAALTQQYKGTNNIAVAFSGDGATNEGSFHESVNMAATWKLPVIFFIINNR
YGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYETMGKAVEHVRGGNGPAIVE
VESYRWFGHSTADAGKYRTKEEVDEWKEKDPMIKYRTYLTSEGIATDDELDAIQAQVKKE
VDDAYEFAQNSPDPELSVAFEDVWVD
NT seq
981 nt
NT seq
+upstream
nt +downstream
nt
atggaggccaaaatggtaacagtttctaaagaacaatatttggatatgttccttaaaatg
gaacgtattcgtgaatttgattcacgtattaacaaactcgtccgtcgtggatttgtacaa
gggatgactcacttctctgttggtgaagaagcagctaacgttggtgcagtggctcacttg
acttacgatgatattattttttcaaatcaccgtggacatggtcaatcaatcgcaaaagat
atggaccttaacaaaatgatggctgaacttgcaggtaaagcaactggtgtttctaaagga
cgcggtggctcaatgcacttggctgactttgaaaaaggaaactatggtaccaatggtatc
gttggtggtggttacgctcttgcagtaggtgcagcgcttacccaacaatataaaggaact
aataacattgctgttgctttctcaggcgatggtgctactaacgaaggatcattccacgag
tctgtcaatatggctgcaacatggaaacttcctgttattttctttatcattaataaccgt
tatggaatctccatgagcattaacaatgcgacaaacacaccgcatttatacacacgtgca
gaagcttacggaattcctggtttctactgtgaagatggcaatgacgtgatggctgtctat
gaaacaatgggcaaagctgttgagcatgttcgtggcggaaacggcccagctattgttgag
gtagaatcataccgttggtttggtcactcaactgcagatgctggtaaataccgtactaaa
gaagaagttgatgagtggaaagaaaaagatccaatgatcaaatatcgtacttatctgaca
agcgaaggcattgccactgatgacgaattggatgccattcaagcacaagtcaaaaaagaa
gttgacgatgcttatgaatttgcacaaaatagtccagatccagaactttcagtagccttc
gaagacgtttgggttgactaa
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