Streptomyces davaonensis: BN159_5678
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Entry
BN159_5678 CDS
T02518
Name
(GenBank) folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sdv
Streptomyces davaonensis
Pathway
sdv00790
Folate biosynthesis
sdv01100
Metabolic pathways
sdv01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sdv00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
BN159_5678
Enzymes [BR:
sdv01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
BN159_5678
6.3.2.17 tetrahydrofolate synthase
BN159_5678
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
CCK30057
UniProt:
K4RA54
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All DBs
Position
6334106..6335590
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AA seq
494 aa
AA seq
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MSESDPFDEIIAEETDRDPDLAVIEAGSRTLRTQGGAPSADVPTRPEDPEVDKALREVEA
ELATRWGETKLEPSVSRIAALMDVLGEPQRSYPSIHITGTNGKTTTARMIEALLGAFELR
TGRYTSPHVQSVTERISLDGAAISAERFIETYNDIKPYIEMVDAAQEYRLSFFEVLTGMA
YAAFADAPVDVAVVEVGMGGSWDATNVIDGDVAVVTPIDLDHTDRLGETPAEIAAEKAGI
VKQDATVILAQQPVDAAQVLLKKAVEVDATVAREGLEFGVVSRQVAVGGQLATLRGLGGE
YPEIYLPLHGAHQAHNAAVALAAVEAFFGVGAVRAEPLDIDTVRKAFAAVASPGRMEVVR
RSPTVVLDAAHNPAGARVTAEAVGEAFDFSRLIGVVGASGDKNVRGLLEAFEPLFAEVVI
TQNSSHRAMDVDELAAIAVEVFGEERVQVEPRLPDALEAAITLAEEEGEFTGGGVLVTGS
VITVGEARLLLGKG
NT seq
1485 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgaaagcgaccccttcgacgagatcatcgcggaagagaccgaccgcgaccccgat
ctcgcggtcatcgaggccggcagccgtaccctccgcacccagggcggagccccgagcgcg
gacgtacccacgcgccccgaggaccccgaggtcgacaaggccctgcgcgaagtcgaagcg
gagctcgccactcggtggggcgagaccaagctggagccctccgtcagccgtatcgccgcg
ctgatggacgtgctgggcgagccgcagcgctcgtacccctcgatccacatcaccggcacg
aacggcaagaccaccacggcccgcatgatcgaggccctgctcggcgccttcgagctgcgg
accggccgatacacctccccgcacgtccagtccgtcaccgagcggatcagcctggacggc
gccgcgatctccgccgagcggttcatcgagacgtacaacgacatcaagccgtacatcgag
atggtcgacgcggcgcaggagtaccggctgtccttcttcgaggtgctgaccggcatggcc
tacgccgccttcgccgacgcgcccgtcgacgtggccgtcgtggaggtcggcatgggcggc
tcctgggacgccaccaacgtcatcgacggtgacgtcgccgtcgtcacccccatcgacctg
gaccacaccgaccggctcggtgagacgcccgccgagatcgccgccgagaaggccggcatc
gtcaagcaggacgcgaccgtcatcctggcccagcaaccggtggacgcggcgcaggtgctg
ctgaagaaggccgtggaggtcgacgcgaccgtcgcccgcgaagggctggagttcggggtg
gtgtcccggcaggtcgccgtcggcggacaactggccaccctgcgcggcctcggcggggag
tacccggagatctacctcccgctgcacggcgcccaccaggcgcacaacgccgccgtggcg
ctggccgccgtggaggcgttcttcggcgtcggtgccgtgcgcgccgagccgctggacatc
gacaccgtccgcaaggccttcgcggccgtcgcctcgccgggccgcatggaggtcgtacgc
cggtcgccgaccgtcgtgctggacgccgcgcacaacccggcgggcgcccgggtgaccgcc
gaggcggtcggcgaggccttcgacttcagccggctgatcggcgtggtcggggccagcggc
gacaagaacgtacgagggctgctggaggccttcgagccgctcttcgccgaggtcgtcatc
acccagaactccagccatcgcgcgatggacgtcgacgaactggccgcgatcgccgtggag
gtgttcggcgaggagcgggtgcaggtcgagccgcggctgccggacgccctggaggccgcg
atcacgctggccgaggaggagggtgagttcaccggcggcggggtgctcgtcaccggttcc
gtcatcacggtcggcgaggcacgactgctgctcgggaagggctga
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