Streptomyces dengpaensis: C4B68_00270
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Entry
C4B68_00270 CDS
T06611
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sdx
Streptomyces dengpaensis
Pathway
sdx00790
Folate biosynthesis
sdx01100
Metabolic pathways
sdx01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sdx00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
C4B68_00270
Enzymes [BR:
sdx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
C4B68_00270
6.3.2.17 tetrahydrofolate synthase
C4B68_00270
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AVH54529
UniProt:
A0A2L2MD54
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Position
49195..50649
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AA seq
484 aa
AA seq
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MTCTCGAVDAVAAMAYLDGLTGYEQTGRLEQPTLERMARLAGALGDPQRAYPVIHLTGTN
GKGSTAAMIASLLSGQGLRVGTYTSPHVTRLAERVTIGGKPVADEALAGAVDRVRQAAVR
AGVTPSWFEAVTAAALWLLAAAGVDVAVIEVGMLGRWDATNVADGAVAVVTNVQLDHTDV
AGPTRAGIAAEKAGIIKPGATLVLGERDPGLRAIFEAQHPARILAAGQEMSWRNRRVTPA
GSLVDLVNLWGTRAGIAVGMFGAHQCDNALLALTAAEAFTGAPIPAAAVTAALGGTQVPG
RFEIVRTSPVVALDGAHNPAGAAALRRTIEESFASVTPRILVYGTLAGRDPVEFLDQAGV
RSADLVVTTEPASPRAMSADLLAGVVRGFGVPVTPVRRPAQALSAAVTAAGRRGLVVATG
SLYLIAPPSEPPPSNARPECFHDRRHPDRARRLPASPRCPAAPGCPGVSPPGPLPGDGDR
QRHA
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atgacctgcacctgcggcgccgtggacgcggtcgcggccatggcgtacctggacgggctg
accggctatgagcagaccggccggctggagcagcccacgcttgagcggatggcccgcctg
gccggcgcgctgggcgacccgcagcgcgcctacccggtcattcacctgaccggcacgaac
gggaagggctccacggccgcgatgatcgccagcttgctgagcggccagggactgcgggtc
gggacctacaccagcccgcatgtcacccggctggccgagcgcgtcacgatcggcgggaag
cccgtcgcggacgaggccctggccggggctgttgaccgggtcaggcaggcggccgtgcgg
gccggggtcacgccgagctggttcgaggcagtgaccgccgccgcgctgtggctgctggcc
gcggccggggtggacgtggccgtgatcgaggtggggatgttgggccgctgggatgccacg
aacgtcgccgacggggcggtggccgtggtcaccaacgtgcagctggaccacacggacgtg
gcgggcccgacgcgggcggggatcgcggcggagaaggcgggcatcatcaagccgggcgcc
accctcgtcctgggggagcgggacccggggctccgggccatcttcgaggcacagcacccg
gcccgcatcctggccgcgggccaggagatgtcctggcgcaaccgccgcgttaccccggct
ggttccctggtcgatctcgtcaacctctgggggacgcgggccgggatcgcagtcggcatg
ttcggcgcgcatcagtgtgacaacgcgctgctggcgctgacagccgccgaggcgttcacc
ggggcgccgatccccgcggccgccgtgaccgccgccctgggcggcacgcaggttcccgga
cgcttcgagatcgtccggaccagcccggtcgtggccctggacggcgcgcacaacccggcc
ggcgcggcggcgctgcgccggaccatcgaggagagctttgcctccgtcacgccccggatc
ctggtctacggcaccctggccggccgggaccccgtcgagttccttgaccaggccggggtc
cggtccgcggacctcgtcgtcaccaccgaaccggcttccccgcgggcaatgtcggccgat
ctccttgccggggtggtccgcggcttcggggtgcccgtcacacccgtcaggcggcccgcg
caggccctttcggccgcggtgaccgcggcgggccgccgcggcctggtcgtcgccacgggc
tcgctatatctcatcgcccccccctcagagccgccgccctcgaacgcccgtccggagtgc
ttccatgaccgccgacaccctgaccgcgcccgccgcctcccggcctcgccccgctgccca
gccgcgccaggatgtcccggggtttccccgccgggaccgctgcctggtgatggggatcgt
caacgtcacgcctga
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