Streptomyces fradiae: CP974_10965
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Entry
CP974_10965 CDS
T07648
Name
(GenBank) uroporphyrinogen-III synthase
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
sfb
Streptomyces fradiae
Pathway
sfb00860
Porphyrin metabolism
sfb01100
Metabolic pathways
sfb01110
Biosynthesis of secondary metabolites
sfb01120
Microbial metabolism in diverse environments
sfb01240
Biosynthesis of cofactors
Module
sfb_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
sfb_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sfb_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sfb00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CP974_10965
Enzymes [BR:
sfb01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CP974_10965
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Gene cluster
GFIT
Motif
Pfam:
HEM4
Trans_reg_C
Motif
Other DBs
NCBI-ProteinID:
QEV12464
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All DBs
Position
complement(2454312..2455457)
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AA seq
381 aa
AA seq
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MHEQQENGPLAGFTVGVTAARRADELGALLQRRGAAVLHAPALRIVPLADDAELLRATAA
LVADAPDVVVATTAIGFRGWLEAADGWGHGEELLACLRRSRILARGPKVKGAVRAAGLTE
EWSPASESMAEVLDRLLEQGVAGLRVALQLHGEPLPGFVEALRDAGAEVVVVPVYRWMPP
EDPAPLDRLLDAVAARTLDAVTFTSAPAAASMLARAEHRGLRADVLEALRHDVLPACVGP
VTAVPLQSRGVDTLQPDRFRLGPLVQLLCRELPARARTLPVAGRRVEIRGHAVLVDGGLR
PVPPAGMALLHALARRPGWVVSRADLLRALPGAGRDEHAVETAMARLRTALGAPNLIQTV
VKRGYRLSLDPTSAPPADGEG
NT seq
1146 nt
NT seq
+upstream
nt +downstream
nt
atgcacgagcagcaggagaacggccccctcgcgggcttcacggtcggtgtcaccgcggcc
cgccgcgcggacgaactgggtgcgctgctgcagcgccggggcgcggccgtgctgcacgcc
ccggccctgcggatcgtgcccctcgccgacgacgcggaactcctccgggcgacagcggcc
ctcgtcgccgacgccccggacgtcgtcgtcgccacgacggcgatcggcttccgcggctgg
ctggaggcggcggacggctgggggcacggggaggaactgctcgcctgcctgcggcggtcg
cggatcctcgcgcgcggccccaaggtgaagggcgccgtacgggcggccgggctgaccgag
gagtggtcgcccgcctccgagtcgatggccgaggtcctcgaccggctcctggagcagggc
gtggccgggctgcgggtcgccctccagctgcacggggagccgctgcccggcttcgtggag
gcgctgcgggacgcgggcgcggaggtcgtggtcgtcccggtttaccggtggatgccgccc
gaggacccggccccgctggaccggctgctggacgcggtcgccgcccgcaccctggacgcg
gtcaccttcaccagcgcgccggccgccgcgtcgatgctggcccgcgccgagcaccggggg
ctgcgcgccgacgtgctggaggcgctgcgccacgacgtgctgccggcgtgcgtcgggccg
gtcaccgccgtgccgctgcagagccggggcgtggacaccctccagccggaccgcttccgg
ctcggcccgctggtccagctcctgtgccgggagctgcccgcgcgggcccggacgctgccg
gtggccgggcggcgcgtcgagatccggggccacgcggtgctggtcgacggcgggctgcgg
cccgtgccgcccgccgggatggcgctgctgcacgcgctggcccgccgccccggctgggtc
gtctcccgtgccgacctgctgcgcgccctgcccggagcgggccgcgacgagcacgccgtg
gagaccgcgatggcccgcctccgcacggccctgggcgccccgaacctgatccagacggtg
gtcaagcgcggctaccggctgtccctcgacccgacgtccgcgccgcccgcggacggggag
ggatag
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