Streptomyces ficellus: EIZ62_22175
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Entry
EIZ62_22175 CDS
T06929
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sfic
Streptomyces ficellus
Pathway
sfic00790
Folate biosynthesis
sfic01100
Metabolic pathways
sfic01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sfic00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
EIZ62_22175
Enzymes [BR:
sfic01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
EIZ62_22175
6.3.2.17 tetrahydrofolate synthase
EIZ62_22175
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QGV80638
UniProt:
A0A6I6FSI0
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Position
4918549..4920057
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AA seq
502 aa
AA seq
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MSEQPPSSDSDDFDDLVEAETTRDPDLAVIEAGSRTLRAQAGPPGADEAVPARPADPEVD
RALREVEQELATRWGETKLEPSVTRIAALMDVLGEPQRAYPSIHITGTNGKTSTARMIEA
LLGAFDLRTGRYTSPHVQSITERISLDGAPVGHERFIETYQDIKPYVEMVDSSQEYRLSF
FEVLTGMAYAAFADAPVDVAVVEVGMGGSWDATNVIDGDVAVVTPIDLDHTDRLGTTHAE
IAGEKAGIIKQGATVILSQQPVDAAQVMLKKAVEVDATVAREGMEFGVVSREVAVGGQLL
TLRGLGGEYEEIFLPLYGAHQAHNAAVALAAVEAFFGVGAQEARTLDVDRIRHAFASVVS
PGRLEVVRRSPTVVLDAAHNPAGGRAAAEGISEAFGFSRLVGVVGTSGDKDVRGLLEAFE
PIFAEVVVTQNSSHRAMDVDELAAIAVEVFGDERVVVEPRLPDALEAAITLAEEEDEFAG
AGVLVTGSVITVGEARLLLGKG
NT seq
1509 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgagcagcccccgtccagcgacagcgacgacttcgacgacctcgtggaagccgag
accacccgagaccccgatctggcggtgatcgaggccggcagccgtacgctgcgcgcccag
gccggaccgcccggggccgacgaggcggtgcccgcgcggcccgccgaccccgaggtggac
cgggcgctgcgggaggtggagcaggagctggccacccgctggggcgagactaagctggag
ccgtcggtgacgcggatcgcggcactgatggacgtgctgggcgagccgcagcgcgcgtac
ccctccatccacatcacgggcaccaacggcaagacgtccacggcccggatgatcgaggcg
ctgctcggcgcgttcgacctgcgcaccgggcggtacacctcgccccacgtgcagtcgatc
accgagcggatcagcctggacggcgcgccggtcggccacgagcggttcatcgagacgtac
caggacatcaagccgtacgtcgagatggtcgactcctcgcaggagtaccggctgtcgttc
ttcgaggtcctcaccggtatggcgtacgccgcgttcgcggacgcgccggtggacgtggcg
gtcgtcgaggtcggcatgggcggcagctgggacgcgacgaacgtgatcgacggggacgtc
gccgtcgtcacccccatcgacctggaccacaccgaccggctgggcaccacgcacgccgag
atcgccggcgagaaggccgggatcatcaagcagggcgccaccgtcatcctttcgcagcag
ccggtggacgcggcgcaggtgatgctgaagaaggccgtcgaggtcgacgcgacggtggcc
cgcgagggcatggagttcggtgtcgtctcgcgggaggtcgccgtcggcgggcagctgctg
acgctgcgcggcctcggcggtgagtacgaggagatcttcctgccgctgtacggcgcgcac
caggcgcacaacgcggcggtggcgctcgcggcggtggaggcgttcttcggcgtcggcgcc
caggaggcgcggacgctggacgtggaccgcatccggcacgcgttcgcctcggtggtctcg
ccgggccgcctggaggtggtgcggcgcagcccgaccgtggtgctggacgccgcgcacaac
ccggcgggcgggcgggccgccgccgagggcatcagcgaggcgttcggcttctcccggctg
gtgggtgtcgtcggcacgagcggcgacaaggacgtccggggcctgctggaggcgttcgag
ccgatcttcgcggaggtcgtcgtcacgcagaactccagccatcgcgcgatggacgtggac
gagctggccgcgatcgccgtcgaggtgttcggcgacgagcgcgtggtggtcgagccgcgg
ctgcccgacgcgctggaggcggccatcaccctggcggaggaagaggacgagttcgccggg
gcgggcgtcctggtgacgggttcggtgatcacggtcggcgaggcccggctgctgctcggg
aagggctga
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