Shigella flexneri NCTC1 (serotype 2a): NCTC1_02567
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Entry
NCTC1_02567 CDS
T03751
Symbol
arnA
Name
(GenBank) bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase,Polymyxin resistance protein PmrI,bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase,Folate-dependent phosphoribosylglycinamide formyltransferase PurN,methionyl-tRNA formyltransferase,NAD dependent epimerase/dehydratase family
KO
K10011
UDP-4-amino-4-deoxy-L-arabinose formyltransferase / UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating) [EC:
2.1.2.13
1.1.1.305
]
Organism
sft
Shigella flexneri NCTC1 (serotype 2a)
Pathway
sft00520
Amino sugar and nucleotide sugar metabolism
sft01100
Metabolic pathways
sft01250
Biosynthesis of nucleotide sugars
sft01503
Cationic antimicrobial peptide (CAMP) resistance
Module
sft_M00761
Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N
Brite
KEGG Orthology (KO) [BR:
sft00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00520 Amino sugar and nucleotide sugar metabolism
NCTC1_02567 (arnA)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01503 Cationic antimicrobial peptide (CAMP) resistance
NCTC1_02567 (arnA)
Enzymes [BR:
sft01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.305 UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating)
NCTC1_02567 (arnA)
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.13 UDP-4-amino-4-deoxy-L-arabinose formyltransferase
NCTC1_02567 (arnA)
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Gene cluster
GFIT
Motif
Pfam:
Epimerase
GDP_Man_Dehyd
Formyl_trans_N
Formyl_trans_C
3Beta_HSD
NAD_binding_10
Sacchrp_dh_NADP
RmlD_sub_bind
NAD_binding_4
Motif
Other DBs
NCBI-ProteinID:
CDX07735
LinkDB
All DBs
Position
1:2343885..2345867
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AA seq
660 aa
AA seq
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MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGSVAHLAAERDIPVYAPD
NVNHPLWVERIAQLSPEVIFSFYYRHLICDEIFQLAPAGAFNLHGSLLPKYCGRAPLNWV
LVNGETETGVTLHRMVKRADAGAIVAQLRVAIAPDDIAITLHHKLCHAARQLLEQTLPAI
KHGNILEIAQRENEATCFGRRTPDDSFLEWHKPASVLHNMVRAVADPWPGAFSYVGNQKF
TVWSSRVHPHASKAQPGSVISVAPLLIACGDGALEIVTGQAGDGITMQGSQLAQMLGLVQ
GSRLNSQPACTARRRTRVLILGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLNHP
HFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYC
VKYRKRIIFPSTSEVYGMCSDKYFDEDHSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEK
EGLQFTLFLPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDI
RDGIEALYHIIENAGNRCDGEIINIGNPENEASIEELGEMLLASFEKHPLRHHFPPFAGF
RVVESSCYYGKGYQDVEHRKPSIRNAHRCLDWEPKIDMQETIDETLDFFLRTVDLTDKPS
NT seq
1983 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaccgtcgtttttgcctaccacgatatgggatgcctcggtattgaagctctgctg
gctgccggttacgaaattagcgccatttttacccataccgataatcccggtgaaaaagcc
ttttatggttcggtggctcatctggcggcggaaagagacattccggtttatgcgccggat
aacgttaatcatccgctgtgggtggaacgcattgcccaactgtcaccagaggtgattttc
tctttttattatcgccatcttatttgcgacgagatttttcagctcgctcccgcaggtgca
tttaatctgcacggttcgctgttaccaaaatattgtggtcgcgcgccgctgaactgggtg
ctggtgaacggtgaaacggaaacgggcgttacattgcaccgaatggtaaaacgtgccgat
gctggggccattgtggcgcaactgcgcgttgccattgcgccagacgatatcgctattacg
ctgcatcataaattgtgccatgccgcgcgccagctactggaacagacattacccgccatt
aaacacggtaatattctggaaatcgcccagcgcgaaaacgaagccacctgttttggtcgc
agaacgccggatgacagtttccttgaatggcataaaccggcatccgtactgcacaacatg
gtacgtgccgttgccgatccgtggccgggtgccttcagctatgttggcaatcagaaattc
accgtctggtcgtcgcgtgttcatcctcatgccagcaaagcacagccggggagcgtgatt
tctgttgcgccactgctgattgcctgtggcgatggcgcgctggaaatcgtcaccggacag
gcgggcgacggcattactatgcagggctcgcaattagcgcagatgctgggcctggtgcaa
ggttcacgcttgaatagccagcctgcctgcaccgcccgacgccgtacccgggtactcatc
ctcggggtgaatggctttattggcaaccatctgacagaacgcctgctgcgcgaagatcat
tatgaagtttacggtctggatattggcagcgatgcgataagccgttttctgaatcatcca
cattttcactttgtcgaaggcgatatcagtattcattccgaatggattgagtatcacgtc
aaaaaatgtgatgtcgtcttgccgctggtggcgatagccacgccgattgaatatacccgc
aacccgctgcgcgtatttgaactcgattttgaagagaatctgcgcattatccgctactgc
gttaagtaccgtaagcgaatcatcttcccgtcaacttcagaagtttatgggatgtgtagc
gataaatacttcgatgaggaccattctaatttaatcgtcggcccggtgaataaaccacgc
tggatttattcggtgtcaaaacaattacttgatcgggtgatctgggcctatggcgaaaaa
gagggtttacagttcaccctcttcctcccgtttaactggatgggaccacgactggataac
cttaatgcagcgcgaattggcagctcccgcgctattacgcaactcattctcaatctggta
gaaggttcaccaattaagctaattgatggcggaaaacaaaaacgctgctttactgatatc
cgggacggtatcgaggcgttgtaccacattatcgaaaatgcgggaaatcgctgcgacggc
gaaattatcaacattggcaatcctgagaacgaagcgagcattgaggaactgggcgagatg
ctgctggcgagcttcgaaaaacatccgctgcgccatcatttcccaccgtttgcgggcttt
cgcgttgtcgaaagtagctgctactacggcaaaggatatcaggacgtagagcatcgtaaa
ccgagcatccgcaatgcccaccgctgcctggactgggagccgaaaattgatatgcaggaa
accatcgacgaaacgctggatttcttcctgcgcaccgttgatcttacggataaaccatca
tga
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