Shigella flexneri 8401 (serotype 5b): SFV_2384
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Entry
SFV_2384 CDS
T00377
Symbol
folC
Name
(GenBank) dihydrofolate synthetase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sfv
Shigella flexneri 8401 (serotype 5b)
Pathway
sfv00790
Folate biosynthesis
sfv01100
Metabolic pathways
sfv01240
Biosynthesis of cofactors
Module
sfv_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
sfv00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SFV_2384 (folC)
Enzymes [BR:
sfv01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SFV_2384 (folC)
6.3.2.17 tetrahydrofolate synthase
SFV_2384 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
ABF04495
UniProt:
Q0T2H0
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Position
complement(2433683..2434951)
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AA seq
422 aa
AA seq
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MIIKRTPQAASPLASWLSYLENLHSKTIDLGLERVSQVAARLGVLKPAPFVFTVAGTNGK
GTTCRTLESILMAAGYKVGVYSSPHLVRYTERVRVQGQELPESAHTASFAEIESARGDIS
LTYFEYGTLSALWLFKQAQLDVVILEVGLGGRLDATNIVDADVAVVTSIALDHTDWLGPD
RESIGREKAGIFRSEKPAIVGEPEMPSTIADVAQEKGALLQRRGVEWNYSVTDHDWAFSD
AHGTLENLPLPLVPQPNAATALAALRASGLEVSENAIRDGIASAILPGRFQIVSESPRVI
FDVAHNPHAAEYLTGRMKALPKNGRVLAVIGMLHDKDIAGTLAWLKSVVDDWYCAPLEGP
RGATAEQLLEHLGNGKSFDSVAQAWDAAMADAKAEDTVLVCGSFHTVAHVMEVIDARRSG
GK
NT seq
1269 nt
NT seq
+upstream
nt +downstream
nt
atgattatcaaacgcactcctcaagccgcgtcgcctctggcttcgtggctttcttatctg
gaaaacctgcacagtaaaactatcgatctcggccttgagcgcgtgagccaggtcgcggcg
cgtcttggcgtcctgaaaccagcgccatttgtgtttaccgttgcgggtacgaatggcaaa
ggcaccacctgccgtacgctggagtcgattctgatggcggcagggtacaaagtgggcgtc
tacagttcgcctcatctggtgcgttataccgagcgcgtacgtgtgcagggccaggaattg
ccggaatcggcccacaccgcctcttttgcggagattgaatcggcacgcggtgatatttcc
ctgacctatttcgagtacggtacgctgtcggcgttgtggctgttcaagcaggcacaactt
gacgtggtgattctggaagtagggctgggcggtcgtctggacgcaaccaatattgtcgat
gccgatgtcgcggtagtaaccagtattgcgctggatcataccgactggctgggtccagat
cgcgaaagtattggtcgcgagaaagcaggcatcttccgcagcgaaaaaccggcaattgtc
ggtgagccggaaatgccttctaccattgctgatgtggcgcaggaaaaaggtgcactgtta
caacgtcggggcgttgagtggaactattccgtcaccgatcatgactgggcgtttagcgat
gctcacggcacgctggaaaatctgccgttgccgcttgtcccgcaaccgaatgccgcaacg
gcgctggcggcactgcgtgccagcgggctggaagtcagtgaaaatgccattcgcgacggg
attgccagcgcaattttgccgggacgtttccagattgtgagcgagtcgccacgcgttatt
tttgatgtcgcgcataatccacatgcggcggaatatctcaccgggcgtatgaaagcgcta
ccgaaaaacgggcgcgtgctggcggttatcggtatgctacatgataaagatattgccgga
actctggcctggttgaaaagcgtggttgatgactggtattgtgcgccactggaagggccg
cgcggtgccacggcagaacaactgcttgagcatttgggtaacggcaaatcatttgatagc
gttgcgcaggcatgggatgccgcaatggcggacgctaaagcggaagacaccgtgctggtg
tgtggttctttccacacggtcgcacatgtcatggaagtgattgacgcgaggagaagcggt
ggcaagtaa
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