Streptomyces griseofuscus: HEP81_05171
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Entry
HEP81_05171 CDS
T07010
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sgf
Streptomyces griseofuscus
Pathway
sgf00790
Folate biosynthesis
sgf01100
Metabolic pathways
sgf01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sgf00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
HEP81_05171
Enzymes [BR:
sgf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
HEP81_05171
6.3.2.17 tetrahydrofolate synthase
HEP81_05171
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QNT95430
UniProt:
A0A7H1Q550
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Position
5662899..5664443
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AA seq
514 aa
AA seq
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MSVGLRRLIPVSDLPHENDQPDPLDPFEEIIEAETDRDPDLAVIEAGSRTLRTQGGAPQA
DVPARPEDPEVDKALREVEAELATRWGETKLEPSVSRISALMDVLGDPQRSYPSIHITGT
NGKTSTARMIECLLGAFELRTGRYTSPHVQSITERISLDGAPVSAERFIETYQDIKPYIE
MVDAAQEYRLSFFEVLTGMAYAAFADAPVDVAVVEVGMGGSWDATNVIDGDVAVVTPIGL
DHTDRLGETTGEIAGEKAGVIKQGATVILAQQPVDAAQVLLKKAVEVDATVAREGLEFGI
VARQVAVGGQMLTLRGLGGEYPEVYLPLHGAHQAHNAAVALAAVEAFFGVGAQRAEPLDI
DTVRKAFAAVSSPGRLEVVRRSPTVVLDAAHNPAGAEATAEAVREAFDFTRLIGVVGASG
DKNVRGLLEAFEPIFAEVVVTQNSSHRAMDADELAAIAVEVFGDERVQVEPRLPDALEAA
ITLAEEEGEFAGGGVLVTGSVITVGEARLLLGKG
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
atgtcagtggggctccgtagactgatacccgtgagcgacctcccgcacgagaacgaccag
cccgatcccctcgacccgttcgaggagatcatcgaggccgagaccgaccgcgaccccgac
ctcgccgtcatcgaggcaggcagccgtaccctgcgtacccagggcggcgcgccgcaggcc
gatgtgcccgcgcggcccgaggacccggaagtcgacaaggcgctgcgcgaggtcgaggcg
gagctggcgacccgctggggcgagaccaagctggagccctcggtcagcaggatctccgcg
ctgatggacgtgctgggcgacccccagcgctcgtacccctcgatccacatcacgggtacg
aacggcaagacctccaccgcccgcatgatcgagtgcctgctcggcgccttcgagctgcgc
accggccgctacaccagcccccatgtgcagtcgatcaccgagcggatcagcctggacggc
gccccggtctccgccgagcgcttcatcgagacgtaccaggacatcaagccgtacatcgag
atggtggacgccgcccaggagtaccggctgtccttcttcgaggtcctcaccggcatggcc
tacgccgccttcgcggacgcgccggtcgacgtggccgtcgtggaggtcggcatgggcggc
tcctgggacgccaccaatgtgatcgacggcgatgtcgccgtcgtcaccccgatcggcctg
gaccacaccgaccgcctcggcgagaccaccggcgagatcgccggcgagaaggccggcgtc
atcaagcagggtgccaccgtcatcctggcccagcagcccgtggacgccgcccaggtgctg
ctgaagaaggccgtggaggtcgacgccaccgtggcccgcgagggcctggagttcggcatc
gtggcccgccaggtcgccgtcggcggacagatgctcaccctgcgcggcctcggcggcgag
taccccgaggtctacctcccgctgcacggcgcccaccaggcgcacaacgcggccgtggcg
ctcgccgccgtggaggccttcttcggcgtcggcgcccagcgtgccgagccgctggacatc
gacaccgtccgcaaggcgttcgccgccgtctcctccccgggccgcctggaggtcgtacga
cgctctcccaccgtcgtcctggacgccgcgcacaacccggccggcgccgaggccaccgca
gaggcggtgcgcgaggcgttcgacttcacgcggctgatcggcgtggtcggcgcgagcggc
gacaagaacgtgcgcgggctgctggaggccttcgagccgatcttcgccgaggtcgtcgtc
acccagaactccagccaccgcgccatggacgcggacgaactggccgccatcgccgtcgag
gtcttcggtgacgagcgggtccaggtcgaaccgaggctgcccgacgccctggaggccgcg
atcacgctggccgaggaggagggcgagttcgcgggcggcggtgtgctggtcaccggttcc
gtcatcacggtcggcgaggcccggctgctgctgggcaagggctga
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