Streptomyces genisteinicus: IAG43_08380
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Entry
IAG43_08380 CDS
T07903
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sgj
Streptomyces genisteinicus
Pathway
sgj00010
Glycolysis / Gluconeogenesis
sgj00020
Citrate cycle (TCA cycle)
sgj00620
Pyruvate metabolism
sgj00785
Lipoic acid metabolism
sgj01100
Metabolic pathways
sgj01110
Biosynthesis of secondary metabolites
sgj01120
Microbial metabolism in diverse environments
sgj01200
Carbon metabolism
sgj01210
2-Oxocarboxylic acid metabolism
Module
sgj_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sgj00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
IAG43_08380 (aceE)
00020 Citrate cycle (TCA cycle)
IAG43_08380 (aceE)
00620 Pyruvate metabolism
IAG43_08380 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
IAG43_08380 (aceE)
Enzymes [BR:
sgj01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
IAG43_08380 (aceE)
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Motif
Pfam:
PDH_E1_M
Transketolase_N
DUF3135
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
QNP62957
UniProt:
A0A7H0HQZ1
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Position
1908649..1911318
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AA seq
889 aa
AA seq
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MTDPVGKLPSELDQLPDRDAEETAEWAASLDAVAEHAGPHRAAYLMRRTLQHAEKAGVAL
PRLLETDYVNTIPTSAEPALDGDEEMEARITAWNRWNAAAMVTRGSRFGVGGHIATFASA
AWLYETGFNHFFRGKEGDGSGDQLYIQGHASPGIYARAFLDGRLTEAHLDNFRQESGGNG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLQGRGIKDTSNSHVWAFLGDGEM
DEPESTAALALASRERLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVVKSL
WGSAWDELFQLDTAGALVRRLREVPDAQFQTYATRDVAYIREHFFGAEPALVELAKLLTD
AKISECFHTSRGGHEARKVYAAYKAALAHKGAPTVILAQTVKGFTLGKGFESKNANHQMK
KLTTDEFKGMRDLLGLPIADSAFADGLVPYGHPGADSPEVRYLQERRAALGGPAPARRLH
ASAPLPEPEERAFAALKKGSGKQEMATTMAFVRLVKDLMRDKQTGKRWVPIVPDEARTFG
MESLFPSAGIYSPLGQTYEPVDRDQLMYYKEAKDGQILNEGITEAGAMADFIAAATSYAT
HGETMIPFYIFYSMFGWQRTGDQMWQLADQLGKGFIVGATAGRTTLTGEGLQHADGHSHL
IAATNPASLNYDPAFAYEIAVIVKDGLRRMYGPDAEDVFYYLTVYNEPKPQPAMPEGVEE
GIVKGLYRFNEGSAGTDAPRLQLLASGTAIHWALAAQELLANDWNVAADVWSATSWGELR
RDALEADEALLRGEERVPYVTQALAGAPGPVLAVSDWMRQVPDQISQWVEQDWSSLGTDG
FGLSDTRDAARRHFGVDPQSIAVAALAQLAKRGEVPASAVKEARERYGL
NT seq
2670 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccgtaggcaagcttccgagcgagctcgaccagctcccggaccgcgacgcc
gaggagaccgccgagtgggcggcctccctcgacgcagtcgcggagcacgccggaccgcac
cgcgccgcgtacctgatgcgccgcacgctccagcacgccgagaaggcgggcgtcgccctg
cccaggctgctggagacggactacgtcaacaccatccccacctccgccgagcccgcgctc
gacggcgacgaggagatggaggcgcgcatcaccgcgtggaaccgctggaacgcggccgcc
atggtgacccgcggctcccggttcggcgtcggcggccacatcgccaccttcgcctccgcg
gcctggctctacgagaccggcttcaaccacttcttccgcggcaaggagggggacggcagc
ggcgaccagctgtacatccagggccacgcctcccccggcatctacgcccgcgccttcctc
gacggccgcctcaccgaggcgcacctcgacaacttccgccaggagtccggcggcaacggc
ctcccctcgtacccgcacccgcgccggctgccctggctgtgggagttcccgacggtctcc
atgggcctcggcccgctgtcggcgatctaccaggcccggttcaaccgctacctccagggc
cgcgggatcaaggacaccagcaactcccacgtctgggccttcctcggcgacggcgagatg
gacgagcccgagtcgaccgcggcactcgccctcgcctcccgcgagcgcctggacaacctg
accttcgtgatcaactgcaacctgcagcgcctcgacggtccggtccgcgccaacttcaag
atcgtgcaggagctggaggcccagttccgcggcgccggctggaacgtcgtgaagtcgctg
tggggttccgcctgggacgagctgttccagctcgacacggcgggcgcgctggtgcgccgc
ctgcgggaggtgccggacgcgcagttccagacgtacgcgacccgcgacgtcgcctacatc
cgcgagcacttcttcggcgccgagccggccctcgtcgagctggcgaaactgctgacggac
gccaagatctccgagtgtttccacacctcccgcggcggccacgaggcccgcaaggtgtac
gcggcgtacaaggcggcgctggcgcacaagggcgcgccgacggtgatcctcgcccagacg
gtcaagggcttcaccctcggcaagggcttcgagtccaagaacgccaaccaccagatgaag
aagctgacgaccgacgagttcaagggcatgcgcgacctgctcggactcccgatcgcggac
agcgccttcgccgacggcctggtgccctacggccacccgggcgccgactcccccgaggtg
cgctacctccaggagcgccgcgccgccctcggcggccccgccccggcccgccgtctgcac
gcttcggcaccgctgcccgagccggaggagcgcgcgttcgccgcgctgaagaagggctcc
ggcaagcaggagatggccacgaccatggcgttcgtccgcctggtcaaggacctgatgcgg
gacaagcagaccgggaagcgctgggtgccgatcgtccccgacgaggcgcgcaccttcggc
atggagtcgctgttcccgtccgcgggcatctactcgccgctgggccagacgtacgagccg
gtcgaccgcgaccagctgatgtactacaaggaggccaaggacggccagatcctcaacgag
gggatcaccgaggccggcgccatggccgacttcatcgccgccgccacgtcgtacgcgacg
cacggcgagacgatgatcccgttctacatcttctactcgatgttcggctggcagcggacc
ggcgaccagatgtggcagctcgccgaccagctcggcaagggcttcatcgtcggcgccacc
gccgggcgcaccacgctgaccggtgagggcctccagcacgccgacggccattcgcacctg
atcgccgccaccaacccggcgtcgctcaactacgacccggcgttcgcgtacgagatcgcg
gtgatcgtcaaggacggtctgcggcggatgtacggccccgacgccgaggacgtcttctac
tacctgacggtctacaacgagccgaagccgcagcccgccatgccggagggcgtggaggag
ggcatcgtcaagggcctgtaccgcttcaacgagggctcggccggcacggacgccccgcgt
ctccagctgctcgcctcgggcacggcgatccactgggccctggcggcccaggagctgctg
gcgaacgactggaacgtggccgccgacgtgtggtccgcgacgtcctggggcgagctgcgc
cgggacgccctggaggcggacgaggccctgctccgcggcgaggagcgcgtcccgtacgtc
acccaggcgctggccggcgcccccggcccggtgctggcggtgtccgactggatgcgccag
gtgccggaccagatcagccagtgggtggagcaggactggtcgtcgctgggcacggacggc
ttcggtctctccgacacccgtgacgcggcccgccgccacttcggcgtggacccgcagtcg
atcgcggtcgccgcgctggcccagctggcgaagcggggcgaggtcccggcgtccgccgtg
aaggaggcgcgcgagcgctacggcctgtag
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