Streptomyces aurantiacus: GCM10017557_55270
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Entry
GCM10017557_55270 CDS
T07085
Name
(GenBank) dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sgm
Streptomyces aurantiacus
Pathway
sgm00790
Folate biosynthesis
sgm01100
Metabolic pathways
sgm01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sgm00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
GCM10017557_55270
Enzymes [BR:
sgm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
GCM10017557_55270
6.3.2.17 tetrahydrofolate synthase
GCM10017557_55270
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
DUF5539
Motif
Other DBs
NCBI-ProteinID:
BCL30668
UniProt:
A0A7G1P5L9
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All DBs
Position
6335460..6336983
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AA seq
507 aa
AA seq
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MSEFSRDSSESDPDDVSDPFDEIVEAETGRDPDLAVIEAGSRTLRTRGGPPPADIPARPD
DPEADKALRQVEAELATRWGETKLEPSVTRIAALMDVLGEPQRAYPAIHITGTNGKTSTA
RMIEALLGAFDLRTGRYTSPHVQSITERISLDGASIPAERFVETYQDIKPYVEMVDAGQE
FRLSFFEVLTGMAYAAFADAPVDVAVVEVGMGGSWDATNVIDGDVAVVTPIDLDHTDRLG
ETPGEIAKEKAGIVKQGATVILAQQPVDAAQVLLKKAVEVDATVAREGLEFGVVSRQVAV
DGQLLTLRGLGGEYEAVYLPLHGAYQAHNAAVALAAVEAFFGVGSQRPEPLDIDTIRKAF
ASVTSPGRLEIVRRSPTVVLDAAHNPAGARATAEAIREVFDFSRLIGIVGSSGDKNVRGL
LEAFEPIFTEVVVTQNSSHRAMDTDELAAIAVEVFGADRVQVEPRLDDALEAAITLAEVE
GEYAGGGVLVTGSVITVGEARLLLGRG
NT seq
1524 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgagttttcgcgcgacagcagtgagtccgacccggacgacgtctccgatccgttc
gacgagatcgtcgaggccgagacgggacgtgatcccgacctggccgtgatcgaggccggc
agccgcaccctgcgcacgcggggcggcccgccgccggccgacatccccgcgcgtcccgac
gacccggaggccgacaaggcgctgcgccaggtcgaggccgagctcgccacacggtggggc
gagaccaagctggagccgtccgtgacgcggatcgccgcgctcatggacgtactcggcgag
ccgcagcgcgcgtaccccgcgatccacatcacggggactaacggcaagacgtcgacggcc
cgcatgatcgaggccctgctcggcgccttcgacctgcgcaccggtcggtacacctcgccg
cacgtccagtcgatcaccgagcggatcagcctggacggggcgtcgatcccggccgagcgg
ttcgtggagacgtaccaggacatcaagccgtacgtcgagatggtcgacgcaggtcaggag
ttccgcctctccttcttcgaggtgctcacgggcatggcgtacgcggccttcgcggacgcg
cccgtcgacgtggccgtcgtggaggtcgggatgggcggcagctgggacgccacgaacgtc
atcgacggggatgtcgccgtggtgacccccatcgatctggaccacaccgaccggctgggg
gagaccccgggggagatcgccaaggagaaggcgggcatcgtcaagcagggggccacggtg
atcctggcccagcagcccgtcgacgccgcccaggtgctgctcaagaaggccgtcgaggtc
gatgccaccgtggcccgtgaagggcttgagttcggtgtggtgagccggcaggtcgcggtc
gacggccagttgctgacgctccgcggtctcggcggggagtacgaagcggtctacctcccg
ctgcacggggcgtaccaggcgcacaacgccgcggtggcgctcgccgccgtggaggcgttc
ttcggcgtcgggtcgcagcggcccgagccgctcgacatcgacacgatccgcaaggccttc
gcgtcggtcacctcgccggggcggctggagatcgtgcgccggtcgccgaccgtcgtgctg
gacgccgcgcacaacccggcgggcgcccgcgcgaccgccgaggcgatccgtgaggtcttc
gacttcagccggctgatcggcatcgtcgggtcgagcggcgacaagaacgtacgagggctc
cttgaggccttcgagccgatcttcaccgaggtcgtcgtcacgcagaactccagccatcgc
gcgatggacacggacgagctcgccgcgatcgccgtcgaggtgttcggggcggaccgggtg
caggtggagccccgtctcgacgacgctctggaggccgcgatcacgctggccgaggtggag
ggcgagtacgcgggcggtggtgtcctcgtgaccggttccgtcatcacggtcggcgaggcc
cggctgctgctggggaggggctga
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